Results 11 to 20 of about 15,941 (260)

Multi‐omics analyses reveal the interaction between colonic microbiota and host in Min and Yorkshire pigs

Animal Research and One Health, EarlyView., 2023
In the present study, we created the weight gain models with Min and Yorkshire pigs and conducted the metagenomics and metabolomics of colon contents and transcriptomics of colon tissue. Further, we revealed the characteristics and functions of the colonic microbiota in Min and Yorkshire pigs and analyzed their interactions with the host. Overall, this
Xiaoyu Huang, Huihui Li, Feng Cheng, Ligang Wang, Guoqing Cao, Lixian Wang, Lijun Shi   +6 more
wiley   +1 more source

Discovery of glycoside hydrolase enzymes in an avicel-adapted forest soil fungal community by a metatranscriptomic approach. [PDF]

PLoS ONE, 2013
To discover the structural and functional novel glycoside hydrolase enzymes from soil fungal communities that decompose cellulosic biomass, transcripts of functional genes in a forest soil were analyzed.
Kazuto Takasaki, Takamasa Miura, Manabu Kanno, Hideyuki Tamaki, Satoshi Hanada, Yoichi Kamagata, Nobutada Kimura   +6 more
doaj   +1 more source

A New Subfamily of Glycoside Hydrolase Family 30 with Strict Xylobiohydrolase Function

Frontiers in Molecular Biosciences, 2021
The Acetivibrioclariflavus (basonym: Clostridium clariflavum) glycoside hydrolase family 30 cellulosomal protein encoded by the Clocl_1795 gene was highly represented during growth on cellulosic substrates.
Casey Crooks, Nathan J. Bechle, Franz J. St John   +2 more
doaj   +1 more source

A Case Study of the Glycoside Hydrolase Enzyme Mechanism Using an Automated QM-Cluster Model Building Toolkit

Frontiers in Chemistry, 2022
Glycoside hydrolase enzymes are important for hydrolyzing the β-1,4 glycosidic bond in polysaccharides for deconstruction of carbohydrates. The two-step retaining reaction mechanism of Glycoside Hydrolase Family 7 (GH7) was explored with different sized ...
Qianyi Cheng, Nathan John DeYonker
doaj   +1 more source

Engineering the stability and the activity of a glycoside hydrolase [PDF]

Protein Engineering Design and Selection, 2010
Glycosidases, the enzymes responsible in nature for the catabolism of carbohydrates, are well-studied catalysts widely used in industrial biotransformations and oligosaccharide synthesis, which are also attractive targets for drug development. Glycosidases from hyperthermophilic organisms (thriving at temperatures > 85 °C) are also interesting models ...
CobucciPonzano Beatrice, Perugino Giuseppe, Rossi Mose, Moracci Marco   +3 more
openaire   +5 more sources

Functional metagenomics reveals novel β-galactosidases not predictable from gene sequences. [PDF]

PLoS ONE, 2017
The techniques of metagenomics have allowed researchers to access the genomic potential of uncultivated microbes, but there remain significant barriers to determination of gene function based on DNA sequence alone.
Jiujun Cheng, Tatyana Romantsov, Katja Engel, Andrew C Doxey, David R Rose, Josh D Neufeld, Trevor C Charles   +6 more
doaj   +1 more source

Biomass-degrading glycoside hydrolases of archaeal origin [PDF]

Biotechnology for Biofuels, 2020
AbstractDuring the last decades, the impact of hyperthermophiles and their enzymes has been intensively investigated for implementation in various high-temperature biotechnological processes. Biocatalysts of hyperthermophiles have proven to show extremely high thermo-activities and thermo-stabilities and are identified as suitable candidates for ...
Marcel Suleiman, Marcel Suleiman, Garabed Antranikian, Anna Krüger   +3 more
openaire   +4 more sources

Increase of intestinal bacterial sialidase activity exacerbates acute colitis in mice

Frontiers in Molecular Biosciences, 2022
The availability of endogenous and dietary carbohydrates in the gastrointestinal tract influences the composition of the gut microbiota. Carbohydrate foraging requires the action of bacterially-encoded glycoside hydrolases, which release mono- and ...
Tobias Hasler, Leticia Tavares-Gomes, Sereina Gut, Meghna Swayambhu, Mario Gysi, Martin Hausmann, Natasha Arora, Thierry Hennet   +7 more
doaj   +1 more source

A mutation map for human glycoside hydrolase genes [PDF]

Glycobiology, 2020
Abstract Glycoside hydrolases (GHs) are found in all domains of life, and at least 87 distinct genes encoding proteins related to GHs are found in the human genome. GHs serve diverse functions from digestion of dietary polysaccharides to breakdown of intracellular oligosaccharides, glycoproteins, proteoglycans and glycolipids. Congenital
Bernard Henrissat, Bernard Henrissat, Oluf Pedersen, Torben Hansen, Eric P. Bennett, Hans H. Wandall, Hassan Y. Naim, Mitali A. Tambe, Hudson H. Freeze, Birthe Gericke, Diab M Husein, Henrik Clausen, Lars Hansen   +12 more
openaire   +7 more sources

Dietary fiber chemical structure determined gut microbiota dynamics

iMeta, Volume 1, Issue 4, December 2022., 2022
The monosaccharide composition and glycosidic bond configuration determine the CAZyme that could hydrolyze it. Thus, bacteria encoding specific CAZyme utilize different structured dietary fibers. Compounded with bacterial interaction, gut microbiota dynamics is synergistically modulated.
Xin Meng, Jun Zheng, Fengqiao Wang, Jie Zheng, Dong Yang   +4 more
wiley   +1 more source