Results 11 to 20 of about 53,769 (227)
Glycoside Hydrolases across Environmental Microbial Communities. [PDF]
PLoS Computational Biology, 2016 Across many environments microbial glycoside hydrolases support the enzymatic processing of carbohydrates, a critical function in many ecosystems. Little is known about how the microbial composition of a community and the potential for carbohydrate ...
Renaud Berlemont, Adam C Martiny
doaj +8 more sources
The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases [PDF]
Nature Communications, 2022 Barley β-d-glucan glucohydrolase is a glycoside hydrolase family 3 (GH3) enzyme critical for growth and development. Here the authors carryout mutagenesis, structural analyses and multi-scale molecular dynamics to examine the binding and conformational ...
Sukanya Luang +12 more
doaj +4 more sources
Curation of characterized glycoside hydrolases of Fungal origin [PDF]
Database, 2011 Fungi produce a wide range of extracellular enzymes to break down plant cell walls, which are composed mainly of cellulose, lignin and hemicellulose. Among them are the glycoside hydrolases (GH), the largest and most diverse family of enzymes active on these substrates.
Murphy, Caitlin +4 more
openaire +6 more sources
Catalytic strategies of glycoside hydrolases [PDF]
, 2018 Glycoside hydrolases (GHs) are enzymes that catalyze the hydrolysis of the glycosidic bond between two carbohydrate residues or a carbohydrate unit linked to a non-carbohydrate aglycon unit. Despite years of research dedicated to GHs, there are still several mechanistic details, relevant for individual GH enzymes, that remain to be investigated.
Petersen, Luis
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Thermostable glycoside hydrolases in Biorefining [PDF]
, 2014 Glycoside hydrolases, which are responsible for the degradation of the major fraction of biomass, the polymeric carbohydrates in starch and lignocellulose, are predicted to gain increasing roles as catalysts in biorefining applications in the future bioeconomy.
Linares-Pastén, Javier +2 more
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GLYCOSIDE HYDROLASES IN APLYSIA FASCIATA: ANALYSIS AND APPLICATIONS
Biotechnology and Genetic Engineering Reviews, 2008 Glycosylation is considered to be an important reaction for the chemical modification of compounds with useful biological activities. Glycoside hydrolases are biotechnologically attractive enzymes which can be used in synthetic reactions for assembling glycosidic linkages with absolute stereoselectivity at an anomeric centre.
A Trincone +3 more
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Transglycosylation by Glycoside Hydrolases - Production and modification of alkyl glycosides [PDF]
, 2015 To enable the transition to a green, bio-based economy, an extensive enzymatic toolbox competitive to traditional chemical procedures is needed. One strong area for enzymes is carbohydrate chemistry, due to the over-functionalized nature of carbohydrates, difficult to handle in traditional chemistry.
Lundemo, Pontus
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Glycoside hydrolases in the biodegradation of lignocellulosic biomass. [PDF]
3 Biotech, 2023 Lignocellulose is a plentiful and intricate biomass substance made up of cellulose, hemicellulose, and lignin. Cellulose and hemicellulose are polysaccharides characterized by different compositions and degrees of polymerization. As renewable resources, their applications are eco-friendly and can help reduce reliance on petrochemical resources.
Lu H +9 more
europepmc +3 more sources
Computer Simulation to Rationalize "Rational" Engineering of Glycoside Hydrolases and Glycosyltransferases. [PDF]
J Phys Chem B, 2022 Glycoside hydrolases and glycosyltransferases are the main classes of enzymes that synthesize and degrade carbohydrates, molecules essential to life that are a challenge for classical chemistry.
Coines J, Cuxart I, Teze D, Rovira C.
europepmc +3 more sources
Allylic Carbocyclic Inhibitors Covalently Bind Glycoside Hydrolases. [PDF]
JACS Au, 2023 Allylic cyclitols were investigated as covalent inhibitors of glycoside hydrolases by chemical, enzymatic, proteomic, and computational methods. This approach was inspired by the C7 cyclitol natural product streptol glucoside, which features a potential ...
Grayfer TD +11 more
europepmc +3 more sources