The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases
Nature Communications, 2022 Barley β-d-glucan glucohydrolase is a glycoside hydrolase family 3 (GH3) enzyme critical for growth and development. Here the authors carryout mutagenesis, structural analyses and multi-scale molecular dynamics to examine the binding and conformational ...
Sukanya Luang +12 more
doaj +3 more sources
Curation of characterized glycoside hydrolases of Fungal origin [PDF]
Database, 2011 Fungi produce a wide range of extracellular enzymes to break down plant cell walls, which are composed mainly of cellulose, lignin and hemicellulose. Among them are the glycoside hydrolases (GH), the largest and most diverse family of enzymes active on these substrates.
Murphy, Caitlin +4 more
openaire +6 more sources
Thermostable glycoside hydrolases in Biorefining [PDF]
, 2014 Glycoside hydrolases, which are responsible for the degradation of the major fraction of biomass, the polymeric carbohydrates in starch and lignocellulose, are predicted to gain increasing roles as catalysts in biorefining applications in the future bioeconomy.
Linares-Pastén, Javier +2 more
openaire +2 more sources
Commonality of Mechanism in Glycoside Hydrolases, Nucleoside Hydrolases, and Phosphorylases: Importance of Side-Chain Conformation Preorganization [PDF]
JACS AuPo-Sen Tseng +3 more
doaj +2 more sources
Allylic Carbocyclic Inhibitors Covalently Bind Glycoside Hydrolases. [PDF]
JACS Au, 2023 Allylic cyclitols were investigated as covalent inhibitors of glycoside hydrolases by chemical, enzymatic, proteomic, and computational methods. This approach was inspired by the C7 cyclitol natural product streptol glucoside, which features a potential ...
Grayfer TD +11 more
europepmc +3 more sources
Transglycosylation by Glycoside Hydrolases - Production and modification of alkyl glycosides [PDF]
, 2015 To enable the transition to a green, bio-based economy, an extensive enzymatic toolbox competitive to traditional chemical procedures is needed. One strong area for enzymes is carbohydrate chemistry, due to the over-functionalized nature of carbohydrates, difficult to handle in traditional chemistry.
Lundemo, Pontus
openaire +2 more sources
Microbial Glycoside Hydrolases in the First Year of Life: An Analysis Review on Their Presence and Importance in Infant Gut [PDF]
Frontiers in Microbiology, 2021 Clara Belzer +2 more
exaly +2 more sources
Genes for degradation and utilization of uronic acid-containing polysaccharides of a marine bacterium Catenovulum sp. CCB-QB4 [PDF]
PeerJ, 2021 Background Oligosaccharides from polysaccharides containing uronic acids are known to have many useful bioactivities. Thus, polysaccharide lyases (PLs) and glycoside hydrolases (GHs) involved in producing the oligosaccharides have attracted interest in ...
Go Furusawa +2 more
doaj +2 more sources
Supplementing with non-glycoside hydrolase proteins enhances enzymatic deconstruction of plant biomass. [PDF]
PLoS ONE, 2012 The glycoside hydrolases (GH) of Caldicellulosiruptor bescii are thermophilic enzymes, and therefore they can hydrolyze plant cell wall polysaccharides at high temperatures. Analyses of two C.
Xiaoyun Su +3 more
doaj +1 more source
Functional metagenomics reveals novel β-galactosidases not predictable from gene sequences. [PDF]
PLoS ONE, 2017 The techniques of metagenomics have allowed researchers to access the genomic potential of uncultivated microbes, but there remain significant barriers to determination of gene function based on DNA sequence alone.
Jiujun Cheng +6 more
doaj +1 more source