Results 31 to 40 of about 50,765 (224)

Genomic and Transcriptomic Evidence for Carbohydrate Consumption Among Microorganisms in a Cold Seep Brine Pool

Frontiers in Microbiology, 2016
The detailed lifestyle of microorganisms in deep-sea brine environments remains largely unexplored. Using a carefully calibrated genome binning approach, we reconstructed partial to nearly-complete genomes of 51 microorganisms in biofilms from the Thuwal
Weipeng Zhang, Wei Ding, Bo Yang, Renmao Tian, Shuo Gu, Haiwei Luo, Pei-Yuan Qian   +6 more
doaj   +1 more source

Lignocellulolytic and Chitinolytic Glycoside Hydrolases: Structure, Catalytic Mechanism, Directed Evolution and Industrial Implementation

, 2020
Lignocellulolytic and chitinolytic glycoside hydrolases are commonly used enzymes in commercial processes and thus are well documented for their vital role in agriculture, textile, paper, food, biofuel and healthcare sectors. Ongoing research is targeted
Chawade, Aakash,, Vetukuri, Ramesh,, Sveriges lantbruksuniversitet.   +2 more
core   +1 more source

Disaccharide phosphorylases: Structure, catalytic mechanisms and directed evolution

Synthetic and Systems Biotechnology, 2021
Disaccharide phosphorylases (DSPs) are carbohydrate-active enzymes with outstanding potential for the biocatalytic conversion of common table sugar into products with attractive properties. They are modular enzymes that form active homo-oligomers. From a
Shangshang Sun, Chun You
doaj   +1 more source

Engineering the stability and the activity of a glycoside hydrolase [PDF]

Protein Engineering Design and Selection, 2010
Glycosidases, the enzymes responsible in nature for the catabolism of carbohydrates, are well-studied catalysts widely used in industrial biotransformations and oligosaccharide synthesis, which are also attractive targets for drug development. Glycosidases from hyperthermophilic organisms (thriving at temperatures > 85 °C) are also interesting models ...
CobucciPonzano Beatrice, Perugino Giuseppe, Rossi Mose, Moracci Marco   +3 more
openaire   +4 more sources

Chapter five - detecting and identifying glycoside hydrolases using cyclophellitol-derived activity-based probes

, 2022
The ability to detect active enzymes in a complex mixture of folded proteins (e.g., secretome, cell lysate) generally relies on observations of catalytic ability, necessitating the development of an activity assay that is compatible with the sample and ...
Overkleeft, H.S., Davies, G.J., McGregor, N.G.S., Carlson, E.E.   +3 more
core   +2 more sources

Structural changes and molecular mechanism study on the inhibitory activity of epigallocatechin against α-glucosidase and α-amylase

Frontiers in Nutrition, 2022
In this study, the inhibition and mechanism of epigallocatechin (EGC) on two key glycoside hydrolases (α-glucosidase, α-amylase) were explored from the molecular structure level.
Ziyi Man, Yi Feng, Jibo Xiao, Hailong Yang, Xiangting Wu   +4 more
doaj   +1 more source

Functional exploration of the glycoside hydrolase family GH113 [PDF]

PLOS ONE, 2022
β-Mannans are a heterogeneous group of polysaccharides with a common main chain of β-1,4-linked mannopyranoside residues. The cleavage of β-mannan chains is catalyzed by glycoside hydrolases called β-mannanases. In the CAZy database, β-mannanases are grouped by sequence similarity in families GH5, GH26, GH113 and GH134.
Couturier, Marie, Touvrey-Loiodice, Mélanie, Terrapon, Nicolas, Drula, Elodie, Buon, Laurine, Chirat, Christine, Henrissat, Bernard, Helbert, William   +7 more
openaire   +5 more sources

Transcriptome Profiling-Based Analysis of Carbohydrate-Active Enzymes in Aspergillus terreus Involved in Plant Biomass Degradation

Frontiers in Bioengineering and Biotechnology, 2020
Given the global abundance of plant biomass residues, potential exists in biorefinery-based applications with lignocellulolytic fungi. Frequently isolated from agricultural cellulosic materials, Aspergillus terreus is a fungus efficient in secretion of ...
Camila L. Corrêa, Glaucia E. O. Midorikawa, Edivaldo Ximenes Ferreira Filho, Eliane Ferreira Noronha, Gabriel S. C. Alves, Roberto Coiti Togawa, Orzenil Bonfim Silva-Junior, Marcos Mota do Carmo Costa, Priscila Grynberg, Robert N. G. Miller   +9 more
doaj   +1 more source

A mutation map for human glycoside hydrolase genes [PDF]

Glycobiology, 2020
Abstract Glycoside hydrolases (GHs) are found in all domains of life, and at least 87 distinct genes encoding proteins related to GHs are found in the human genome. GHs serve diverse functions from digestion of dietary polysaccharides to breakdown of intracellular oligosaccharides, glycoproteins, proteoglycans and glycolipids. Congenital
Hansen, Lars, Husein, Diab, Gericke, Birthe, Hansen, Torben, Pedersen, Oluf, Tambe, Mitali, Freeze, Hudson, Naim, Hassan, Henrissat, Bernard, Wandall, Hans, Clausen, Henrik, Bennett, Eric   +11 more
openaire   +4 more sources

Microbial glycoside hydrolases as antibiofilm agents with cross-kingdom activity

, 2017
Significance The production of biofilms is an important strategy used by both bacteria and fungi to colonize surfaces and to enhance resistance to killing by immune cells and antimicrobial agents.
Filler, Elan E, Shane R. Baistrocchi, Scott G. Filler, Filler, Scott G, Howell, P Lynne, Brendan D. Snarr, Matthew R. Parsek, P. Lynne Howell, Parsek, Matthew R, Lehoux, Mélanie, Yukiko Sato, Gravelat, Fabrice N, Hong Liu, Robert P. Cerone, Baker, Perrin, Bamford, Natalie C, Baistrocchi, Shane R, Fabrice N. Gravelat, Donald C. Sheppard, Hanna Ostapska, Sato, Yukiko, Perrin Baker, Liu, Hong, Natalie C. Bamford, Snarr, Brendan D, Mélanie Lehoux, Elan E. Filler, Sheppard, Donald C, Ostapska, Hanna, Cerone, Robert P   +29 more
core   +2 more sources