Results 31 to 40 of about 3,083 (198)

A mutation map for human glycoside hydrolase genes [PDF]

Glycobiology, 2020
Abstract Glycoside hydrolases (GHs) are found in all domains of life, and at least 87 distinct genes encoding proteins related to GHs are found in the human genome. GHs serve diverse functions from digestion of dietary polysaccharides to breakdown of intracellular oligosaccharides, glycoproteins, proteoglycans and glycolipids. Congenital
Hansen, Lars, Husein, Diab, Gericke, Birthe, Hansen, Torben, Pedersen, Oluf, Tambe, Mitali, Freeze, Hudson, Naim, Hassan, Henrissat, Bernard, Wandall, Hans, Clausen, Henrik, Bennett, Eric   +11 more
openaire   +4 more sources

Structural changes and molecular mechanism study on the inhibitory activity of epigallocatechin against α-glucosidase and α-amylase

Frontiers in Nutrition, 2022
In this study, the inhibition and mechanism of epigallocatechin (EGC) on two key glycoside hydrolases (α-glucosidase, α-amylase) were explored from the molecular structure level.
Ziyi Man, Yi Feng, Jibo Xiao, Hailong Yang, Xiangting Wu   +4 more
doaj   +1 more source

Microbial glycoside hydrolases as antibiofilm agents with cross-kingdom activity

, 2017
Significance The production of biofilms is an important strategy used by both bacteria and fungi to colonize surfaces and to enhance resistance to killing by immune cells and antimicrobial agents.
Filler, Elan E, Shane R. Baistrocchi, Scott G. Filler, Filler, Scott G, Howell, P Lynne, Brendan D. Snarr, Matthew R. Parsek, P. Lynne Howell, Parsek, Matthew R, Lehoux, Mélanie, Yukiko Sato, Gravelat, Fabrice N, Hong Liu, Robert P. Cerone, Baker, Perrin, Bamford, Natalie C, Baistrocchi, Shane R, Fabrice N. Gravelat, Donald C. Sheppard, Hanna Ostapska, Sato, Yukiko, Perrin Baker, Liu, Hong, Natalie C. Bamford, Snarr, Brendan D, Mélanie Lehoux, Elan E. Filler, Sheppard, Donald C, Ostapska, Hanna, Cerone, Robert P   +29 more
core   +2 more sources

Transcriptome Profiling-Based Analysis of Carbohydrate-Active Enzymes in Aspergillus terreus Involved in Plant Biomass Degradation

Frontiers in Bioengineering and Biotechnology, 2020
Given the global abundance of plant biomass residues, potential exists in biorefinery-based applications with lignocellulolytic fungi. Frequently isolated from agricultural cellulosic materials, Aspergillus terreus is a fungus efficient in secretion of ...
Camila L. Corrêa, Glaucia E. O. Midorikawa, Edivaldo Ximenes Ferreira Filho, Eliane Ferreira Noronha, Gabriel S. C. Alves, Roberto Coiti Togawa, Orzenil Bonfim Silva-Junior, Marcos Mota do Carmo Costa, Priscila Grynberg, Robert N. G. Miller   +9 more
doaj   +1 more source

Development and validation of a microarray for the investigation of the CAZymes encoded by the human gut microbiome. [PDF]

PLoS ONE, 2013
Distal gut bacteria play a pivotal role in the digestion of dietary polysaccharides by producing a large number of carbohydrate-active enzymes (CAZymes) that the host otherwise does not produce.
Abdessamad El Kaoutari, Fabrice Armougom, Quentin Leroy, Bernard Vialettes, Matthieu Million, Didier Raoult, Bernard Henrissat   +6 more
doaj   +1 more source

Identification of d-arabinan-degrading enzymes in mycobacteria

Nature Communications, 2023
Bacterial cell growth and division require the coordinated action of enzymes that synthesize and degrade cell wall polymers. Here, we identify enzymes that cleave the d-arabinan core of arabinogalactan, an unusual component of the cell wall of ...
Omar Al-Jourani, Samuel T. Benedict, Jennifer Ross, Abigail J. Layton, Phillip van der Peet, Victoria M. Marando, Nicholas P. Bailey, Tiaan Heunis, Joseph Manion, Francesca Mensitieri, Aaron Franklin, Javier Abellon-Ruiz, Sophia L. Oram, Lauren Parsons, Alan Cartmell, Gareth S. A. Wright, Arnaud Baslé, Matthias Trost, Bernard Henrissat, Jose Munoz-Munoz, Robert P. Hirt, Laura L. Kiessling, Andrew L. Lovering, Spencer J. Williams, Elisabeth C. Lowe, Patrick J. Moynihan   +25 more
doaj   +1 more source

Structural studies of Glycoside Hydrolases

, 2021
Glycoside hydrolases (E.C 3.2.1.-) are enzymes that catalyze the cleavage of glycosidic bonds in oligosaccharides, complex sugars and various glycoconjugates. In this work structures of B. thetaiotaomicron β-1,4-mannosidase, B.
Anar, Batzorig
core  

Detected glycoside hydrolases (GH) and carbohydrate-binding modules (CBM) within related Curtobacterium spp. strains.

, 2021
Detected glycoside hydrolases (GH) and carbohydrate-binding modules (CBM) within related Curtobacterium spp. strains.
Nemanja Kuzmanović (5696690), Valeria Carpentieri-Pipolo (11642657), Ivica Dimkić (2822084), Vibha Bhardwaj (11642654), Giuliano Degrassi (6396539)   +4 more
core   +1 more source

Identification of Carbohydrate Metabolism Genes in the Metagenome of a Marine Biofilm Community Shown to Be Dominated by Gammaproteobacteria and Bacteroidetes

, 2010
Polysaccharides are an important source of organic carbon in the marine environment and degradation of the insoluble and globally abundant cellulose is a major component of the marine carbon cycle.
Joint, IR, Edwards, JL, Connolly, J, Edwards, Jennifer L, Joint, Ian, McCarthy, Alan J, McDonald, James E; id_orcid, Darren L. Smith, Smith, Darren, Clive Edwards, Jennifer L. Edwards, McDonald, James, McDonald, JE, Edwards, C, James E. McDonald, Smith, DL, Edwards, Jennifer, Ian Joint, Smith, Darren L, Cox, MJ, Cox, Michael, Connolly, John, John Connolly, Michael J. Cox, McCarthy, AJ, McCarthy, Alan, Cox, Michael J; id_orcid, Edwards, Clive, Alan J. McCarthy   +28 more
core   +1 more source

Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut [PDF]

Open Biology, 2016
The human gastrointestinal tract harbours myriad bacterial species, collectively termed the microbiota, that strongly influence human health. Symbiotic members of our microbiota play a pivotal role in the digestion of complex carbohydrates that are ...
Glyn R. Hemsworth, Andrew J. Thompson, Judith Stepper, Łukasz F. Sobala, Travis Coyle, Johan Larsbrink, Oliver Spadiut, Ethan D. Goddard-Borger, Keith A. Stubbs, Harry Brumer, Gideon J. Davies   +10 more
doaj   +1 more source