Results 61 to 70 of about 162,319 (334)

Development and validation of a microarray for the investigation of the CAZymes encoded by the human gut microbiome. [PDF]

PLoS ONE, 2013
Distal gut bacteria play a pivotal role in the digestion of dietary polysaccharides by producing a large number of carbohydrate-active enzymes (CAZymes) that the host otherwise does not produce.
Abdessamad El Kaoutari, Fabrice Armougom, Quentin Leroy, Bernard Vialettes, Matthieu Million, Didier Raoult, Bernard Henrissat   +6 more
doaj   +1 more source

Interlinked GTPase cascades provide a motif for both robust switches and oscillators [PDF]

J. R. Soc. Interface 16, 20190198 (2019), 2019
GTPases regulate a wide range of cellular processes, such as intracellular vesicular transport, signal transduction, and protein translation. These hydrolase enzymes operate as biochemical switches by toggling between an active guanosine triphosphate (GTP)-bound state and an inactive guanosine diphosphate (GDP)-bound state.
arxiv   +1 more source

Rewiring of the seed metabolome during Tartary buckwheat domestication

Plant Biotechnology Journal, Volume 21, Issue 1, Page 150-164, January 2023., 2023
Summary Crop domestication usually leads to the narrowing genetic diversity. However, human selection mainly focuses on visible traits, such as yield and plant morphology, with most metabolic changes being invisible to the naked eye. Buckwheat accumulates abundant bioactive substances, making it a dual‐purpose crop with excellent nutritional and ...
Hui Zhao, Yuqi He, Kaixuan Zhang, Shijuan Li, Yong Chen, Ming He, Feng He, Bin Gao, Di Yang, Yu Fan, Xuemei Zhu, Mingli Yan, Nathalie Giglioli‐Guivarc'h, Christophe Hano, Alisdair R. Fernie, Milen I. Georgiev, Dagmar Janovská, Vladimir Meglič, Meiliang Zhou   +18 more
wiley   +1 more source

Crystal Structure of Thermotoga maritima α-Glucosidase AglA Defines a New Clan of NAD+-dependent Glycosidases [PDF]

, 2003
Glycoside hydrolase family 4 represents an unusual group of glucosidases with a requirement for NAD(+), divalent metal cations, and reducing conditions. The family is also unique in its inclusion of both alpha- and beta-specific enzymes.
Hoffmann, Volker, Liebl, Wolfgang, Lodge, Jacinta A., Maier, Timm, Sträter, Norbert   +4 more
core   +1 more source

Identification of d-arabinan-degrading enzymes in mycobacteria

Nature Communications, 2023
Bacterial cell growth and division require the coordinated action of enzymes that synthesize and degrade cell wall polymers. Here, we identify enzymes that cleave the d-arabinan core of arabinogalactan, an unusual component of the cell wall of ...
Omar Al-Jourani, Samuel T. Benedict, Jennifer Ross, Abigail J. Layton, Phillip van der Peet, Victoria M. Marando, Nicholas P. Bailey, Tiaan Heunis, Joseph Manion, Francesca Mensitieri, Aaron Franklin, Javier Abellon-Ruiz, Sophia L. Oram, Lauren Parsons, Alan Cartmell, Gareth S. A. Wright, Arnaud Baslé, Matthias Trost, Bernard Henrissat, Jose Munoz-Munoz, Robert P. Hirt, Laura L. Kiessling, Andrew L. Lovering, Spencer J. Williams, Elisabeth C. Lowe, Patrick J. Moynihan   +25 more
doaj   +1 more source

Conformational free energies of methyl-$α$-L-iduronic and methyl-$β$-D-glucuronic acids in water [PDF]

J. Chem. Phys. 132, 104108 (2010), 2009
We present a simulation protocol that allows for efficient sampling of the degrees of freedom of a solute in explicit solvent. The protocol involves using a non-equilibrium umbrella sampling method, in this case the recently developed adaptively biased molecular dynamics method, to compute an approximate free energy for the slow modes of the solute in ...
arxiv   +1 more source

The hemicellulose-degrading enzyme system of the thermophilic bacterium Clostridium stercorarium: comparative characterisation and addition of new hemicellulolytic glycoside hydrolases

Biotechnology for Biofuels, 2018
BackgroundThe bioconversion of lignocellulosic biomass in various industrial processes, such as the production of biofuels, requires the degradation of hemicellulose.
J. Broeker, M. Mechelke, Melanie Baudrexl, Denise Mennerich, Daniel Hornburg, M. Mann, W. Schwarz, W. Liebl, V. Zverlov   +8 more
semanticscholar   +1 more source

Targeted metagenomics of active microbial populations with stable-isotope probing [PDF]

, 2016
The ability to explore microbial diversity and function has been enhanced by novel experimental and computational tools. The incorporation of stable isotopes into microbial biomass enables the recovery of labeled nucleic acids from active microorganisms,
Abu Laban, Abu Laban, Albertsen, Alneberg, Antony, Bernard, Chapleur, Chemerys, Chen, Chen, Chen, Colin, Cébron, Dumont, Dumont, Eyice, Faoro, Ferrer, Fu, Grob, Gupta, Gutierrez, Héry, Imelfort, J Colin Murrell, Jayamani, Jennifer Pratscher, Josh D Neufeld, Kalyuhznaya, Kim, Kim, Kim, Laban, Lear, Lee, Lee, Li, Li, Li, Lu, Lueders, Lynch, Martin, Moussard, Neufeld, Neufeld, Neufeld, Neufeld, Nyyssonen, Osaka, Paes, Pinnell, Pinnell, Qian, Radajewski, Saidi-Mehrabad, Sara Coyotzi, Schwarz, Singleton, Singleton, Song, Sul, Tyson, Verastegui, Vieites, Wang, Woyke, Yin   +67 more
core   +1 more source

Investigating the defoliating‐like (DL) VCG2A pathotype of Verticillium dahliae through identification and prediction of secreted proteins from genomes of Australian isolates

Plant Pathology, Volume 72, Issue 2, Page 334-341, February 2023., 2023
A defoliating‐like VCG2A Verticillium dahliae isolate was observed to have 20 secreted proteins in common with virulent phenotypes; interestingly half of these were most closely related to proteins from a VCG6 isolate. Abstract In Australia, recent investigations have reported the presence of a number of Verticillium dahliae pathotypes (VCG1A, VCG2A ...
John Webster, Pearl Dadd‐Daigle, Toni A. Chapman, Karen Kirkby   +3 more
wiley   +1 more source

Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut [PDF]

Open Biology, 2016
The human gastrointestinal tract harbours myriad bacterial species, collectively termed the microbiota, that strongly influence human health. Symbiotic members of our microbiota play a pivotal role in the digestion of complex carbohydrates that are ...
Glyn R. Hemsworth, Andrew J. Thompson, Judith Stepper, Łukasz F. Sobala, Travis Coyle, Johan Larsbrink, Oliver Spadiut, Ethan D. Goddard-Borger, Keith A. Stubbs, Harry Brumer, Gideon J. Davies   +10 more
doaj   +1 more source