Results 71 to 80 of about 26,122 (235)
Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.We report a super‐resolution strategy that maps cholesterol‐rich membrane domains in whole, intact cells with an effective spatial resolution of ∼40 nm by combining expansion microscopy with a perfringolysin O domain 4 probe. This approach enables direct visualization of the spatial association between CD20 and CD38 complexes and cholesterol‐rich ...
Gang Wen +9 more
wiley +2 more sources
Exosomes as Carriers of Alzheimer's Amyloid-ß
Frontiers in Neuroscience, 2017 The intracerebral level of the aggregation-prone peptide, amyloid-ß (Aß), is constantly maintained by multiple clearance mechanisms, including several degradation enzymes, and brain efflux.
Kohei Yuyama, Yasuyuki Igarashi
doaj +1 more source
Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine
Phytotherapy Research, EarlyView.By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao +11 more
wiley +1 more source
Glycosphingolipids of human thyroid
Lipids, 1974 AbstractGlycosphingolipids were isolated from total lipids of female and male human thyroids by alkaline hydrolysis, silicic acid, diethylaminoethyl‐celluose and thin layer chromatography and analyzed by gas liquid chromatography. On the basis of their mobility in two dimensions on thin layer chromatography, IR analysis, and of sugar molar ratio, four ...
Karli, J.N., Levis, G.M.
openaire +3 more sources
FUT3-AS1 regulates the FUT3-mediated glycosphingolipid biosynthesis pathway.
, 2022 (A) Volcano plot showing the effect of FUT3-AS1 on the differentially expression proteins (DEPs) in IPEC-J2 cells by iTRAQ proteome analysis. IPEC-J2 cells co-transfected with siNC or siFUT3-AS1-1 vector.
Song Gao (131209) +6 more
core +1 more source
Circulating Lipoprotein Sphingolipids in Chronic Kidney Disease with and without Diabetes
BiomedicinesAbnormalities of sphingolipid metabolism play an important role in diabetes. We compared sphingolipid levels in plasma and in isolated lipoproteins between healthy control subjects and two groups of patients, one with chronic kidney disease without ...
Maria F. Lopes-Virella +4 more
doaj +1 more source
Journal of Lipid Research, 2000 In the present study, 2,2,6,6-tetramethylpiperidinooxy nitroxide (TEMPO) has been applied successfully to discriminate between glucosylceramide in the outer and inner leaflets of closed membrane bilayers.
Daniel J. Sillence +4 more
doaj +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objective To investigate the middle ear microbiome in Meniere's disease (MD) patients. Methods Middle ear smears from 10 MD patients (ME group) and 10 chronic suppurative otitis patients (OE group) were collected during surgery and processed via 16S rRNA gene sequencing.
Yu‐Ting Tao +3 more
wiley +1 more source
Comparative investigation of glycosphingolipid composition of Japanese pilchard head [PDF]
, 1997 The distribution and composition of glycosphingolipid in the head that of Japanese pilchard were studied. The head (wet weight=81.4g) was removed from six Japanese pilchards.
田中, 伸子 +5 more
core +1 more source
Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.A 310‐helix‐mediated conformational switch promotes a front‐face SNi‐like catalysis by human A4GALT. Mechanism‐guided design identifies AdaGalCer as a selective modulator of globotriaosylceramide (Gb3) biosynthesis, opening a clear route toward new Fabry disease therapeutics.
Nicky de Koster +13 more
wiley +2 more sources