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Elevated serum glucosylsphingosine level in children with obesity: relation to plasma atherogenesis. [PDF]
Salah NY +5 more
europepmc +1 more source
Glycosphingolipids are amphiphilic plasma membrane components formed by a glycan linked to a specific lipid moiety. In this chapter we report on these compounds, on their role played in our cells to maintain the correct cell biology.In detail, we report on their structure, on their metabolic processes, on their interaction with proteins and from this ...
Elena, Chiricozzi +10 more
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Glycosphingolipids and Insulin Resistance
Glycosphingolipids are structural membrane components, residing largely in the plasma membrane with their sugar-moieties exposed at the cell's surface. In recent times a crucial role for glycosphingolipids in insulin resistance has been proposed. A chronic state of insulin resistance is a rapidly increasing disease condition in Western and developing ...
Aerts, J.M. +15 more
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Glycosphingolipids and insulin resistance
Progress in Lipid Research, 2009Obesity is associated with an increased risk for insulin resistance, a state characterized by impaired responsiveness of liver, muscle and adipose tissue to insulin. One class of lipids involved in the development of insulin resistance are the (glyco)sphingolipids. Ceramide, the most simple sphingolipid, directly inhibits phosphorylation of the insulin
Mirjam Langeveld, Johannes M F G Aerts
exaly +3 more sources
Characterization of Glycosphingolipids in the Human Parathyroid and Thyroid Glands
As part of a systematic investigation of the glycosphingolipids in human tissues, acid and non-acid glycosphingolipids from human thyroid and parathyroid glands were isolated and characterized with mass spectrometry and binding of carbohydrate ...
Karin Saljo +2 more
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Glycosphingolipids participate in brain development, intestinal tract maturation, and defense against gut pathogens. Here, we performed a qualitative and quantitative comparison of milk glycosphingolipids from secretors and nonsecretors.
Jiangbo Fan +2 more
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