Results 181 to 190 of about 17,138 (226)

Porcine intestinal glycosphingolipids recognized by F6-fimbriated enterotoxigenic Escherichia coli

Microbial Pathogenesis, 2014
One important virulence factor of enterotoxigenic Escherichia coli is their ability to adhere via fimbrial adhesins to specific receptors located on the intestinal mucosa. Here, the potential glycosphingolipid receptors of enterotoxigenic F6-fimbriated E.
Annelies Coddens, John Benktander, Eric Cox   +2 more
exaly   +3 more sources

A General Chemoenzymatic Strategy for the Synthesis of Glycosphingolipids [PDF]

European Journal of Organic Chemistry, 2016
A concise, prototypical, and stereoselective strategy for the synthesis of therapeutically and immunologically significant glycosphingolipids has been developed.
Yunpeng Liu, Liuqing Wen, Lei Li
exaly   +2 more sources

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HPLC of Glycosphingolipids and Phospholipids

2021
This chapter reviews HPLC methodology developed for the analysis of the glycosphingolipids and phospholipids, which are ubiquitious components of biological membranes. The isolation and measurement of glycosphingolipids and phospholipids are essential for many studies on complex biological systems.
R H, McCluer, M D, Ullman, F B, Jungalwala   +2 more
openaire   +2 more sources

Biochemistry of glycosphingolipid degradation

Clinica Chimica Acta, 1997
Glycosphingolipids (GSLs) form cell-type-specific patterns on the surface of eukaryotic cells. Degradation of GSLs requires endocytotic membrane flow of plasma membrane-derived GSLs into the lysosomes as the digesting organelles. Recent research focused on the mechanisms leading to selective membrane degradation in the lysosomes and on the mechanism ...
K, Sandhoff, T, Kolter
openaire   +2 more sources

Glycosphingolipids and cell death

Glycoconjugate Journal, 2003
Sphingolipids have been implicated in various cellular processes including growth, cell-cell or ligand-receptor interactions, and differentiation. In addition to their importance as reservoirs of metabolites with important signaling properties, sphingolipids also help provide structural order to plasma membrane lipids and proteins within the bilayer ...
Meryem, Bektas, Sarah, Spiegel
openaire   +2 more sources

Glycosphingolipids in membrane architecture

Journal of Supramolecular Structure, 1977
AbstractAs part of a program to investigate the behavior and interactions of glycolipids in biological membranes we have synthesized spin‐labeled derivatives of 2 families of carbohydrate‐bearing ceramides (glycosphingolipids): simple neutral glycolipids and gangliosides.
F J, Sharom, C W, Grant
openaire   +2 more sources

Topology of glycosphingolipid degradation

Trends in Cell Biology, 1996
Glycosphingolipids (GSLs) form cell-type-specific patterns on the surface of eukaryotic cells. Degradation of plasma-membrane-derived GSLs in the lysosomes after internalization through the endocytic pathway is achieved through the concerted actions of hydrolysing enzymes and sphingolipid activator proteins.
K, Sandhoff, T, Kolter
openaire   +2 more sources

The roles of glycosphingolipids in the proliferation and neural differentiation of mouse embryonic stem cells

Experimental and Molecular Medicine, 2009
Glycosphingolipids including gangliosides play important regulatory roles in cell proliferation and differentiation. UDP-glucose:ceramide glucosyltransferase (Ugcg) catalyze the initial step in glycosphingolipids biosynthesis pathway. In this study, Ugcg
Ji-Ung Jung, Kinarm Ko, Kisung Ko
exaly   +2 more sources

Soluble Adamantyl Glycosphingolipid Analogs as Probes of Glycosphingolipid Function

2006
Despite the extensive structural characterization of glycosphingolipids (GSLs), their functions in cell physiology and pathobiology remain elusive. This is largely owing to the fact that they are difficult to handle, being insoluble in aqueous media, and that no one gene alone determines their synthesis. The heterogeneity of the lipid moiety provides a
Clifford, Lingwood, Skanda, Sadacharan, Maan, Abul-Milh, Murugespillai, Mylvaganum, Marcus, Peter   +4 more
openaire   +2 more sources

The Degradation of Glycosphingolipids by Air

Journal of Biochemistry, 1997
Exposure of glycosphingolipids to air irreversibly destroys the integrity of these lipids within a few hours. It was established that among the natural constituents of air, ozone, at commonly observed daytime levels, is responsible for the observed degradation.
R, Jennemann, B L, Bauer, H, Wiegandt
openaire   +2 more sources