Results 171 to 180 of about 347,689 (338)

Mucin Glycoprotein Nanoparticles Enable a Selective Antisense Therapy for Oncogenic MicroRNAs

open access: yesAdvanced NanoBiomed Research, EarlyView.
Mucin glycoproteins are turned into nanoparticles by employing synthetic DNA strands, which have a dual function: they stabilize the nanoparticles and act as binding sites for intracellular miRNA‐21. Thus, upon internalization into tumor cells, these mucin nanoparticles can deplete miRNA‐21 from the cytosol, which induces apoptosis in vitro and in vivo.
Ceren Kimna   +9 more
wiley   +1 more source

Identification of novel neutralizing determinants for protection against HCV

open access: yesHepatology, EarlyView., 2022
Identification of novel neutralizing determinants for protection against hepatitis C virus. Abstract Background and Aims HCV evasion of neutralizing antibodies (nAb) results in viral persistence and poses challenges to the development of an urgently needed vaccine.
Garazi P. Alzua   +12 more
wiley   +1 more source

P16.01.B DOXORUBICIN GLYCOSYLATION AS A NOVEL APPROACH TO SPECIFICALLY TARGET GLIOBLASTOMA [PDF]

open access: bronze
Anna Lisa Iorio   +13 more
openalex   +1 more source

Modification of the glycosylation of extracellular vesicles alters their biodistribution in mice

open access: hybrid, 2019
Félix Royo   +4 more
openalex   +2 more sources

IntegratingMultiple MS Techniques for in-Depth AntibodyGlycosylation Analysis: Revealing Glycosylation-Dependent Structuraland Functional Properties

open access: green
Yuye Zhou (6433229)   +7 more
openalex   +1 more source

Exhaustive glycosylation, pegylation, and glutathionylation of a [G4]‐ene48 dendrimer via photoinduced thiol‐ene coupling

open access: green, 2011
Mauro Lo Conte   +6 more
openalex   +2 more sources

Prothrombotic Activation of Platelet Pannexin‐1 Channels in Antiphospholipid Syndrome

open access: yesArthritis &Rheumatology, EarlyView.
Objective ATP is released from platelets through both degranulation and pannexin‐1 (PANX1) channels. ATP then activates P2X receptors to amplify platelet activation via calcium‐dependent signaling. The objective of this study was to evaluate the role of platelet PANX1 channels in the pathophysiology of antiphospholipid syndrome (APS), an acquired ...
Bruna de Moraes Mazetto Fonseca   +13 more
wiley   +1 more source

Glycosylation of GETV E2 promotes pathogenesis in animal models

open access: hybrid
Ning Shi   +9 more
openalex   +1 more source

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