Results 61 to 70 of about 191,408 (290)
Frontiers in Immunology, 2018 Post-translational modifications such as glycosylation play an important role in the functions of homeostatic proteins, and are critical driving factors of several diseases; however, the role of glycosylation in autoimmune hepatitis is poorly understood.
Xiaohua Hao +10 more
doaj +1 more source
Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
Advanced Healthcare Materials, EarlyView.This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández +4 more
wiley +1 more source
Current Biology, 2019 Eichler introduces the diversity of protein glycosylations and the roles of these modifications in regulating protein function.
openaire +2 more sources
Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives
Advanced Materials, EarlyView.Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi +4 more
wiley +1 more source
Advanced Materials Interfaces, EarlyView.We present a glycan‐mediated strategy for covalent grafting of extracellular matrix proteins onto polystyrene surfaces. This approach preserves protein bioactivity and enhances cell adhesion and viability. Using fibronectin and vitronectin, we demonstrate stable immobilization via glycosylation sites, offering a promising route for advanced ...
Mathilde Hindié +6 more
wiley +1 more source
The Intersection of Glycosylation and Ferroptosis in Cancer
AntioxidantsFerroptosis, an iron-dependent form of regulated cell death characterized by lipid peroxidation, has emerged as a critical mechanism in cancer biology and therapy.
Jihan Kim, Junghyun Kim, Man S. Kim
doaj +1 more source
IEEE Access, 2020 Glycosylation is the most complex post-modification effect of proteins. It participates in many biological processes in the human body and is closely related to many disease states.
Ching-Hsuan Chien +5 more
doaj +1 more source
Advanced Therapeutics, EarlyView.This study characterizes a camelid antibody (B10) with potent neutralizing activity against SARS‐CoV‐2 Wildtype and Omicron variants. Through binding assays, epitope mapping, pseudovirus neutralization, and AI‐driven modeling, the antibody is shown to target conserved RBD regions in a closed Spike conformation.
Katja Hanack +13 more
wiley +1 more source
N-glycosylation of the protein disulfide isomerase Pdi1 ensures full Ustilago maydis virulence.
PLoS Pathogens, 2019 Fungal pathogenesis depends on accurate secretion and location of virulence factors which drive host colonization. Protein glycosylation is a common posttranslational modification of cell wall components and other secreted factors, typically required for
Miriam Marín-Menguiano +4 more
doaj +1 more source
Mechanobiological Dynamics‐Inspired Mechanomodulatory Biomaterials
Advanced Science, EarlyView.Recent advances in biomaterial‐mediated mechanomodulation of stem cell fate, encompassing 2, 3, and 4D systems and their synergy with artificial intelligence is overviewed. By integrating knowledge from diverse fields, this review ultimately aims to inspire the design of smarter biomaterial systems that can accelerate the clinical translation of ...
Letao Yang +6 more
wiley +1 more source