Results 101 to 110 of about 29,448 (207)

Structure of the glycosylphosphatidylinositol membrane anchor of human placental alkaline phosphatase [PDF]

, 1994
The glycosylphosphatidylinositol membrane anchor of human placental alkaline phosphatase was isolated by exhaustive proteolysis followed by hydrophobic interaction chromatography.
Ferguson, Michael A. J.; id_orcid, Thomas-Oates, Jane E., Ikehara, Yukio, Ogata, Shigenori, Redman, Christopher A.   +4 more
core   +1 more source

Synthesis of new fluorescently labeled glycosylphosphatidylinositol (GPI) anchors

, 2011
The borondipyrromethene (BODIPY) labeled new glycosylphosphatidylinositol (GPI) molecules were synthesized as cellular probes to study the chemical basis of microdomain organization of GPI-anchored proteins and cholesterol in plasma membrane.
Yadav, Mahipal, Sawant, Sanghapal D., Saikam, Varma, Gannedi, Veeranjaneyulu, Mahipal Yadav, Parvinder Pal Singh, Sanghapal D. Sawant, Raghupathy, Riya, Varma Saikam, Ram A. Vishwakarma, Riya Raghupathy, Qazi, Naveed A., Vishwakarma, Ram A., Singh, Parvinder Pal, Veeranjaneyulu Gannedi, Naveed A. Qazi   +15 more
core   +1 more source

Structures of glycosylphosphatidylinositol membrane anchors from Saccharomyces cerevisiae*

, 1993
Metabolic labeling studies suggest that Saccharomyces cerevisiae contains many glycoproteins that are anchored in the lipid bilayer by glycosylphosphatidylinositol membrane anchors.
McConville, Malcolm J., Desponds, Chantal, Conzelmann, Andreas, Ferguson, Michael A. J.; id_orcid, Thomas-Oates, Jane E., Fankhauser, Christoph, Homans, Steve W.   +6 more
core   +1 more source

Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer

Cell Reports
Summary: CD24 is frequently overexpressed in ovarian cancer and promotes immune evasion by interacting with its receptor Siglec10, present on tumor-associated macrophages, providing a “don’t eat me” signal that prevents targeting and phagocytosis by ...
Alok K. Mishra, Tianyi Ye, Shahid Banday, Ritesh P. Thakare, Chinh Tran-To Su, Ngoc N.H. Pham, Amjad Ali, Ankur Kulshreshtha, Shreya Roy Chowdhury, Tessa M. Simone, Kai Hu, Lihua Julie Zhu, Birgit Eisenhaber, Sara K. Deibler, Karl Simin, Paul R. Thompson, Michelle A. Kelliher, Frank Eisenhaber, Sunil K. Malonia, Michael R. Green   +19 more
doaj   +1 more source

Structural insights into the inhibition mechanism of fungal GWT1 by manogepix

Nature Communications
Glycosylphosphatidylinositol (GPI) acyltransferase is crucial for the synthesis of GPI-anchored proteins. Targeting the fungal glycosylphosphatidylinositol acyltransferase GWT1 by manogepix is a promising antifungal strategy.
Xinli Dai, Xuanzhong Liu, Jialu Li, Hui Chen, Chuangye Yan, Yaozong Li, Hanmin Liu, Dong Deng, Xiang Wang   +8 more
doaj   +1 more source

Glycosylphosphatidylinositol [PDF]

, 2020
openaire   +1 more source

Glycosylphosphatidylinositols of Protozoan Parasites

Trends in Glycoscience and Glycotechnology, 2012
Tsai, Y., Grube, M., Seeberger, P., Varón Silva, D.   +3 more
openaire   +3 more sources

Glycosylphosphatidylinositol Anchors [PDF]

, 2003
L. M. Thomson, T. Fontaine, A. Mehlert, M. A. J. Ferguson   +3 more
openaire   +1 more source

Chemistry [PDF]

A new, bifunctional glycosylphosphatidylinositol (GPI) derivative containing the highly conserved core structure of all natural GPI anchors with a photoactivable diazirine in the lipid chain and clickable alkynes in the glycan was synthesized by a ...

core  

A novel <i>GWT1</i> A397T substitution combined with <i>TAC1B</i> F214I reduces manogepix susceptibility and fosmanogepix efficacy in <i>Candida auris</i>. [PDF]

Microbiol Spectr
Hirayama T, Kitahori N, Ishimine M, Nakada N, Ito Y, Iwanaga N, Takazono T, Miyazaki T, Izumikawa K, Yanagihara K, Makimura K, Tsukamoto K, Mukae H.   +12 more
europepmc   +1 more source