Results 81 to 90 of about 29,448 (207)

Data for identification of GPI-anchored peptides and ω-sites in cancer cell lines

Data in Brief, 2016
We present data obtained using a focused proteomics approach to identify the glycosylphosphatidylinositol (GPI)-anchored peptides in 19 human cancer cell lines.
Yusuke Masuishi, Yayoi Kimura, Noriaki Arakawa, Hisashi Hirano   +3 more
doaj   +1 more source

Cross-talks of glycosylphosphatidylinositol biosynthesis with glycosphingolipid biosynthesis and ER-associated degradation

Nature Communications, 2020
Glycosylphosphatidylinositol (GPI) anchors are found on many cell surface proteins but their biosynthesis is not fully understood. Here, the authors identify genes involved in GPI galactosylation and reveal functional connections between GPI processing ...
Yicheng Wang, Yusuke Maeda, Yi-Shi Liu, Yoko Takada, Akinori Ninomiya, Tetsuya Hirata, Morihisa Fujita, Yoshiko Murakami, Taroh Kinoshita   +8 more
doaj   +1 more source

Uptake and intracellular stability of glycosylphosphatidylinositol-specific phospholipase D in neuroblastoma cells.

, 1997
Glycosylphosphatidylinositol-specific phospholipase D from mammalian serum has been described to be relatively stable towards the action of proteases in vitro, and it has been speculated that the enzyme may only be active on glycosylphosphatidylinositol ...
Bütikofer P, Brodbeck U, Wiesmann UN, Hari T   +3 more
core   +1 more source

Biallelic mutations in PIGP cause developmental and epileptic encephalopathy

Annals of Clinical and Translational Neurology, 2019
Developmental and epileptic encephalopathies are characterized by infantile seizures and psychomotor delay. Glycosylphosphatidylinositol biosynthesis defects, resulting in impaired tethering of various proteins to the cell surface, represent the ...
Martin Krenn, Alexej Knaus, Dominik S. Westphal, Saskia B. Wortmann, Tilman Polster, Friedrich G. Woermann, Michael Karenfort, Ertan Mayatepek, Thomas Meitinger, Matias Wagner, Felix Distelmaier   +10 more
doaj   +1 more source

Biomedical applications of glycosylphosphatidylinositol-anchored proteins

Journal of Lipid Research, 2016
Glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-APs) use a unique posttranslational modification to link proteins to lipid bilayer membranes. The anchoring structure consists of both a lipid and carbohydrate portion and is highly conserved in ...
Susanne Heider, John A. Dangerfield, Christoph Metzner   +2 more
doaj   +1 more source

Prenatal Presentation of Muggenthaler‐Chowdhury‐Chioza Syndrome Caused by Compound Heterozygous Variants in HYAL2

Prenatal Diagnosis, EarlyView.
Pauline Planté‐Bordeneuve, Anne‐Cécile Leroy‐Tarissi, Marine Tessarech, Pauline Gras, Anne Dieux‐Coëslier, Morgane Stichelbout, Sonia Bouquillon, Thomas Smol   +7 more
wiley   +1 more source

Plasma Lipidomic Features of Adolescent Major Depressive Disorder and Lipid Changes After Fluoxetine Treatment

CNS Neuroscience &Therapeutics, Volume 32, Issue 11, November 2026.
Dysregulated plasma lipid homeostasis with aberrant triglycerides, lysophospholipids, and membrane sphingolipids represents a core pathological feature of adolescent major depressive disorder. Eight‐week fluoxetine treatment remodels lipid profiles including bile acid metabolites and modulates key signaling pathways, supporting novel lipid‐based ...
Chenxi Liu, Yao Li, Hanchen Hou, Jiamei Guo, Bingjie Qin, Xiaoxia Xu, Yuqian He, Tingting Lei, Fei Chen, Lige Zhang, Quanbing Liu, Li Gao, Jiaqi Shi, Haoran Xing, Teng Teng, Tian Qiu, Xinyu Zhou   +16 more
wiley   +1 more source

Lost and Found: Western Honey Bee (Apis mellifera) Matrix Metalloproteinase 1

Ecology and Evolution, Volume 16, Issue 11, November 2026.
Despite considerable overall improvements in the Western honey bee (Apis mellifera) reference genome over the past two decades, some genes are missing in the current reference assembly (Amel_HAv3.1), potentially interfering with the meaningfulness of downstream analyses.
Jessica Braunisch, Ken Werner, Ulrich R. Ernst, Christian W. W. Pirk, Anja Buttstedt   +4 more
wiley   +1 more source

Mycetoma: A Narrative Review of Its Clinical and Epidemiological Spectrum With a Focus on Iran

Health Science Reports, Volume 9, Issue 11, November 2026.
ABSTRACT Background and Aims Mycetoma is a chronic, neglected tropical disease affecting the skin and subcutaneous tissues, capable of extending to deeper structures. It exists in two forms: eumycetoma (fungal) and actinomycetoma (bacterial). This review aims to examine the epidemiology, causative organisms, pathogenesis, clinical features, diagnosis ...
Shabnam Rezaei, Khadijeh Jaberi, Maryam Meskini, Seyed Davar Siadat, Abolfazl Fateh   +4 more
wiley   +1 more source

Cellular Prion Protein Coupling to ADAM‐mediated Release of Small Extracellular Vesicles: Pathological Implications in Prostate Cancer Cells

Journal of Extracellular Biology, Volume 5, Issue 11, November 2026.
ABSTRACT The plasma membrane‐anchored cellular prion protein (PrPC), which is well‐known for its role in prion and prion‐like neurodegenerative diseases, has emerged as a critical player in cancer biology. Elevated PrPC expression and consequent dysregulation of physiological PrPC signalling pathways have been reported in multiple human tumours and are
Chloé Bizingre, Flavien Picard, Florence Roussel, Clara Bianchi, Aurélie Alleaume‐Butaux, Maud Chevé, Hector Ardila‐Osorio, Mathéa Pietri, Grégory Lavieu, Anne Baudry, Benoit Schneider   +10 more
wiley   +1 more source