Results 71 to 80 of about 23,191 (186)

Recombinant Artemin‐Fc Fusion Protein Attenuates TLR4/NF‐κB‐Associated Neuroinflammation and Modulates Inhibitory/Excitatory Synaptic Marker Expression After Spinal Cord Injury

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
Intrathecal ARTN‐Fc treatment attenuates TLR4/NF‐κB‐associated neuroinflammation, promotes microglia/macrophage polarization towards an anti‐inflammatory phenotype, and improves functional recovery after spinal cord injury. ARTN‐Fc also modulates inhibitory/excitatory synaptic marker expression in the L4–L5 spinal dorsal horn, which may contribute to ...
Wenjie Lu, Yurong Tu, Renkai Wang, Minghao Jiang, Junyu Zhuang, Jiahui Song, Ping Wu, Sunren Sheng, Sipin Zhu, Zhouguang Wang   +9 more
wiley   +1 more source

Integrin α5β1 in pancreatic ductal adenocarcinoma: Tumour‒stroma crosstalk, hypoxia and therapeutic targeting

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
ITGA5/integrin α5β1 promotes PDAC progression by integrating fibronectin‐dependent adhesion, hypoxia‐associated ECM remodelling, pancreatic stellate cell/cancer‐associated fibroblast activation, desmoplasia and tumour‒stroma crosstalk. These processes contribute to impaired drug delivery and therapeutic resistance.
Chenzhe Ma, Yingying Wang, Yumin Li
wiley   +1 more source

Fast sleep spindles as a potential prognostic marker of developmental outcome in infantile epileptic spasms syndrome

Epilepsia Open, Volume 11, Issue 4, Page 1227-1236, August 2026.
Abstract Objective The presence or absence of sleep spindles in patients with infantile epileptic spasms syndrome (IESS) has been proposed as a potential predictor of cognitive outcome; however, the validity of this predictor remains uncertain.
Kento Ohta, Thomas Reuben, Tohru Okanishi, Go Yoshino, Tatsuo Hosoda, Kentaro Okada, Yoshihiro Maegaki   +6 more
wiley   +1 more source

Association of SOGPI in mediating the effect of Phosphatidylcholine on polycystic Ovary Syndrome

Gynecological Endocrinology
Background Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder in women of reproductive age, marked by hormonal imbalances and disruptions in glucose and lipid metabolism.
Qian Guo, Wei Wang, Jie Chen, Wei-rong Ma, Yingqian Yang, Yong Tan   +5 more
doaj   +1 more source

Concurrent Loss of PIGA and ZRSR2 in a Patient With Paroxysmal Nocturnal Hemoglobinuria and Myelodysplastic Neoplasm

International Journal of Laboratory Hematology, EarlyView.
Fatma AlBulushi, Eric McGinnis
wiley   +1 more source

Keratan Sulfate: An Electroconductive Glycosaminoglycan at the Interface of Sensory Perception and Neural Signaling

Journal of Neuroscience Research, Volume 104, Issue 8, August 2026.
Laboratory studies show KS has electroconductive properties with the ability to trap and transport protons in neurotransductive processes (Grotthuss proton shuttling). This maintains electrochemical gradients and fluxes at the neuronal cell surface in neural activation. Such processes are central to neuronal cell signaling and communication.
James Melrose
wiley   +1 more source

Detection of paroxysmal nocturnal hemoglobinuria clones in patients with myelodysplastic syndromes and related bone marrow diseases, with emphasis on diagnostic pitfalls and caveats

Haematologica, 2009
Background The presence of paroxysmal nocturnal hemoglobinuria clones in the setting of aplastic anemia or myelodysplastic syndrome has been shown to have prognostic and therapeutic implications. However, the status of paroxysmal nocturnal hemoglobinuria
Sa A. Wang, Olga Pozdnyakova, Jeffrey L. Jorgensen, L. Jeffrey Medeiros, Dariusz Stachurski, Mary Anderson, Azra Raza, Bruce A. Woda   +7 more
doaj   +1 more source

Molecular recognition in plant root endosymbiosis

The Plant Journal, Volume 127, Issue 3, August 2026.
SUMMARY Root endosymbiosis is one of the most intimate types of plant–microbe interactions in which a symbiont is hosted within a living plant cell. In this symbiosis, nitrogen‐fixing bacteria and arbuscular mycorrhizal fungi support plant nutrient provisioning in exchange for carbohydrates and lipids.
Tora Fougner‐Økland, Maria Spezzati, Katarzyna Parys   +2 more
wiley   +1 more source

Inherited glycosylphosphatidylinositol deficiency disorders: a new group of inherited metabolic disorders

Pediatria Polska
Inherited glycosylphosphatidylinositol deficiency disorders (IGDs) are a group of rare congenital disorders of glycosylation with multisystemic involvement.
Michał Patalan, Alicja Leśniak, Justyna Paprocka, Agnieszka Zubkiewicz-Kucharska, Kaja Giżewska-Kacprzak, Marta Glińska, Lidia Babiak-Choroszczak, Maria Giżewska, Robert Śmigiel   +8 more
doaj   +1 more source

Paroxysmal nocturnal hemoglobinuria clones in severe aplastic anemia patients treated with horse anti-thymocyte globulin plus cyclosporine

Haematologica, 2010
Background Clones of glycosylphosphatidylinositol-anchor protein-deficient cells are characteristic in paroxysmal nocturnal hemoglobinuria and are present in about 40–50% of patients with severe aplastic anemia.
Phillip Scheinberg, Michael Marte, Olga Nunez, Neal S. Young   +3 more
doaj   +1 more source