Results 121 to 130 of about 40,853 (234)

The Critical Role of GALNTs‐Regulated O‐GalNAc Glycosylation in Cancer Malignancy

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
The GALNT family initiates mucin‐type O‐GalNAc glycosylation in the Golgi apparatus and how regulatory mechanisms, including GALNT relocalization and microRNA control, modulate this process. Dysregulated O‐GalNAc glycosylation alters key cellular behaviors and promotes cancer malignancy, highlighting its relevance to tumor progression as well as its ...
Jiahao Liu, Sihan Wu, Ge Zhang, Jiehan Li, Yuhan Yin, Aman Uiiah, Sanfei Peng, Yang Fu   +7 more
wiley   +1 more source

Paroxysmal nocturnal hemoglobinuria clones in severe aplastic anemia patients treated with horse anti-thymocyte globulin plus cyclosporine

Haematologica, 2010
Background Clones of glycosylphosphatidylinositol-anchor protein-deficient cells are characteristic in paroxysmal nocturnal hemoglobinuria and are present in about 40–50% of patients with severe aplastic anemia.
Phillip Scheinberg, Michael Marte, Olga Nunez, Neal S. Young   +3 more
doaj   +1 more source

Glycosylphosphatidylinositol (GPI)-Anchored Proteins.

Biological and Pharmaceutical Bulletin, 2002
From the numerous studies developed at the last quarter of the 20th century, glycosylphosphatidylinositol (GPI) anchor has been established as a unique mode of protein binding to the plasma membrane. The core structure of this anchor consists of ethanolamine phosphate, trimannoside, glucosamine and inositol phospholipid in this order.
openaire   +3 more sources

Insulin-induced glycosylphosphatidylinositol (GPI) binding to red cell membrane proteins [PDF]

Journal of the Serbian Chemical Society, 2002
In this work GPI binding to membrane proteins from erythrocytes of insulinoma patients for whom prolonged hyperinsulinism and hypoglycemia were characteristic, as well as from normal erythrocytes incubated with supraphysiological concentrations of ...
NENAD TOMASEVIC, VESNA NIKETIC, MILAN NIKOLIC   +2 more
doaj  

A conserved signalling network regulates Epichloë festucae cell-cell fusion and the mutualistic symbiotic interaction between E. festucae and Lolium perenne : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy (PhD) in Genetics at Massey University, Manawatu, New Zealand [PDF]

, 2016
Content redacted from thesis due to copyright reasons: Figure 1.1 Page 4 Schardl, C. L. (2001) Epichloë festucae and related mutualistic symbionts of grasses. Fungal Genet. Biol., 33, 69-82.
Green, Kimberly Anne
core  

Keratinocytes from human skin respond as typical immune cells after the stimulation with _Trichophyton rubrum_ [PDF]

, 2007
_Trichophyton rubrum_ is the main agent causing dermatophytosis (1). Keratinocytes are considered to be the first physical barrier of defense against pathogens (2). But not only a physical barrier.
Alfonso E. Islas-Rodrí, Luz A. Garcí   +1 more
core   +1 more source

Targeting the GPI transamidase subunit GPAA1 abrogates the CD24 immune checkpoint in ovarian cancer

Cell Reports
Summary: CD24 is frequently overexpressed in ovarian cancer and promotes immune evasion by interacting with its receptor Siglec10, present on tumor-associated macrophages, providing a “don’t eat me” signal that prevents targeting and phagocytosis by ...
Alok K. Mishra, Tianyi Ye, Shahid Banday, Ritesh P. Thakare, Chinh Tran-To Su, Ngoc N.H. Pham, Amjad Ali, Ankur Kulshreshtha, Shreya Roy Chowdhury, Tessa M. Simone, Kai Hu, Lihua Julie Zhu, Birgit Eisenhaber, Sara K. Deibler, Karl Simin, Paul R. Thompson, Michelle A. Kelliher, Frank Eisenhaber, Sunil K. Malonia, Michael R. Green   +19 more
doaj   +1 more source

Structural insights into the inhibition mechanism of fungal GWT1 by manogepix

Nature Communications
Glycosylphosphatidylinositol (GPI) acyltransferase is crucial for the synthesis of GPI-anchored proteins. Targeting the fungal glycosylphosphatidylinositol acyltransferase GWT1 by manogepix is a promising antifungal strategy.
Xinli Dai, Xuanzhong Liu, Jialu Li, Hui Chen, Chuangye Yan, Yaozong Li, Hanmin Liu, Dong Deng, Xiang Wang   +8 more
doaj   +1 more source

Glycosylphosphatidylinositol [PDF]

, 2020
openaire   +1 more source

Glycosylphosphatidylinositols of Protozoan Parasites

Trends in Glycoscience and Glycotechnology, 2012
Tsai, Y., Grube, M., Seeberger, P., Varón Silva, D.   +3 more
openaire   +3 more sources