Results 31 to 40 of about 14,063 (274)

Glycyrrhizin-Based Hydrogels Accelerate Wound Healing of Normoglycemic and Diabetic Mouse Skin

open access: yesPharmaceutics, 2022
Efficient wound repair is crucial for mammalian survival. Healing of skin wounds is severely hampered in diabetic patients, resulting in chronic non-healing wounds that are difficult to treat.
Maarten A. Mees   +15 more
doaj   +1 more source

Exploring the Effect of Compound Glycyrrhizin and Silybinin on the Metabolism of Pexidartinib in Rats Based on CYP3A4 and CYP2C9

open access: yesAdvances in Pharmacological and Pharmaceutical Sciences, 2023
Pexidartinib offered a new therapeutic option for adult patients with symptomatic tenosynovial giant cell tumor (TGCT) who were refractory to surgical treatment and had severe morbidity or functional limitations. Meanwhile, the metabolism of pexidartinib
Yanding Su   +5 more
doaj   +1 more source

Birth outcome in relation to licorice consumption during pregnancy.

open access: yes, 2001
A role for glucocorticoids is suspected in the etiology of low birth weight. The authors tested whether maternal consumption of glycyrrhizin (an inhibitor of cortisol metabolism) in licorice affects birth weight in humans. A sample of 1,049 Finnish women
Järvenpää, AL   +3 more
core   +1 more source

Phytochemical composition, health effects and crop management of liquorice (Glycyrrhiza glabra L.): a medicinal plant [PDF]

open access: yes, 2016
Liquorice has been widely appreciated as an important medicinal plant. Its rhizomes and roots have been used for centuries in traditional medicine due to their renowned therapeutic properties.
Ferreira, Isabel C.F.R.   +3 more
core   +1 more source

Research progress of glycyrrhizin in the treatment of osteoarthritis

open access: yesKouqiang hemian waike zazhi
Glycyrrhizin is extracted from licorice root and has anti-inflammatory, antioxidant, anti-tumor, anti-viral and other effects. At present, there are few studies on the role and mechanism of glycyrrhizin in osteoarthritis.
HU Zhihui, LONG Xing
doaj   +1 more source

Application of Monoclonal Antibodies against Bioactive Natural Products: Eastern Blotting and Preparation of Knockout Extract

open access: yesInternational Journal of Analytical Chemistry, 2012
Matrix-assisted laser desorption/ionization (MALDI) tof mass spectrometry was used for the confirmation of hapten number in synthesized antigen. As application of MAb, the MAbs against ginsenosides and glycyrrhizin have been prepared resulting in the ...
Hiroyuki Tanaka   +8 more
doaj   +1 more source

DOSE DEPENDENT EFFECT OF GLYCYRRHIZIN ON GLYCAEMIC CONTROL OF TYPE 2 DIABETIC RATS

open access: yesKhyber Medical University Journal, 2020
OBJECTIVE: To assess the effect of low and high dose of glycyrrhizin on body weight, fasting blood sugar level (FBSL), serum insulin and glycemic indices in high fat diet induced type 2 diabetic rats.
Mufakhara Fatimah   +5 more
doaj   +1 more source

Physiological correlation between glycyrrhizin, glycyrrhizin‐binding lipoxygenase and casein kinase II [PDF]

open access: yesFEBS Letters, 1996
By means of glycyrrhizin (GL)‐affinity column chromatography, a GL‐binding lipoxygenase (gbLOX) was selectively purified from the partially purified soybean LOX‐1 fraction. Polypeptide analysis of the purified gbLOX by SDS‐PAGE detected two distinct polypeptides (p96 and p94), which were identical to LOX‐3 as determined by their partial N‐terminal ...
Shimoyama, Yoshihito   +5 more
openaire   +2 more sources

LC-MS/MS standardization and validation of glycyrrhizin from the roots of Taverniera cuneifolia: A potential alternative source of Glycyrrhiza glabra

open access: yesHeliyon, 2022
Glycyrrhizin is a triterpene glycoside derived from Glycyrrhiza glabra and related species which is a renowned phytochemical used to cure a variety of ailments such as inflammation, sore throat, hepatitis etc.
Padamnabhi S. Nagar   +2 more
doaj   +1 more source

Cardamonin Commands the Colonic Metabolite Columbianetin Acetate to Compete Against LPS in Binding HMGB1 in the Kidney, Preventing Lipopolysaccharide‐Induced Renal Tubular Pyroptosis

open access: yesFood Frontiers, EarlyView.
Cardamonin upregulate sd the intestinal metabolite columbianetin acetate, which competitively bound HMGB1 to prevent LPS‐induced renal tubular cell pyroptosis (the figure is created with BioRender). ABSTRACT Sepsis‐associated acute kidney injury (SA‐AKI) results in high mortality due to the lack of effective interventions. The current study reports the
Zihui Zhou   +6 more
wiley   +1 more source

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