Results 241 to 250 of about 24,909,638 (279)

Inflammation and psychomotor retardation in depression: The moderating role of glymphatic system.

Brain, behavior, and immunity
BACKGROUND Psychomotor retardation (PMR) is a predominant symptom in patients with major depressive disorder (MDD). The relationship between inflammation and PMR is the subject of ongoing debate.
Qunjun Liang, Bo Peng, Shengli Chen, Hongyue Wei, Shiwei Lin, Xiaoshan Lin, Ying Li, Yingli Zhang, Zhifeng Zhou, Ziyun Xu, Gangqiang Hou, Yingwei Qiu   +11 more
semanticscholar   +1 more source

Vortioxetine Improves Brain Glymphatic System Function, Functional Connectivity, and Cognitive Functions in Major Depressive Disorder

Depression and Anxiety
Background: The therapeutic effects of vortioxetine on mood and cognition have been documented in major depressive disorder (MDD). This study aims to examine whether vortioxetine can improve brain glymphatic system function and connections among ...
Zixuan Guo, Xinyue Tang, S. Zhong, Guanmao Chen, Pan Chen, Chao Chen, Ruoyi Chen, Li Huang, Yanbin Jia, Ying Wang   +9 more
semanticscholar   +1 more source

Therapeutic effects of adipose-derived mesenchymal stem cells combined with glymphatic system activation in prion disease

Molecular Neurodegeneration
There is currently no effective therapy for prion diseases. The glymphatic system is an organized system of perivascular spaces that facilitates the removal of metabolic waste from the brain.
Mohammed Zayed, Yong-Chan Kim, B. Jeong
semanticscholar   +1 more source

Adult Hydrocephalus and the Glymphatic System

Neurosurgery Clinics of North America
Adult hydrocephalus, especially idiopathic normal pressure hydrocephalus (iNPH), involves cerebrospinal fluid (CSF) dysfunction that is associated with impaired waste clearance in the brain, potentially causing toxic protein buildup. This condition shares features with neurodegenerative diseases like Alzheimer's, where amyloid-β and tau proteins ...
openaire   +2 more sources

The glymphatic system

2023
Graham Dupont, R. Shane Tubbs
openaire   +2 more sources

Expansion of White Matter Hyperintensities is Associated with the Glymphatic System Dysfunction in Cerebral Small Vessel Disease.

Brain Research Bulletin
OBJECTIVES To explore the relationship between the glymphatic system and various patterns of white matter hyperintensities (WMHs) in the early stages of cerebral small vessel disease (CSVD), as well as their impact on cognitive function.
Bang Zeng, Peng Zeng, Yayun Xiang, Yuling Peng, Dan Luo, Binglan Li, Ying Chai, Dan Wang, Lisha Nie, Yongmei Li   +9 more
semanticscholar   +1 more source

The glymphatic system in oncology: from the perspective of a radiation oncologist

Journal of Radiation Research
The brain and spinal cord, which constitute the central nervous system, were historically considered immune-privileged sites, as it was believed they lacked an equivalent to the systemic lymphatic system.
Kentaro Nishioka, M. Kawamura, M. Iima, D. Ueda, Rintaro Ito, T. Saida, Ryo Kurokawa, Koji Takumi, Akihiko Sakata, Satoru Ide, M. Honda, Masahiro Yanagawa, S. Sugawara, S. Oda, Tadashi Watabe, K. Sofue, Kenji Hirata, Shinji Naganawa   +17 more
semanticscholar   +1 more source

Dexmedetomidine and the glymphatic system: a new perspective in managing postoperative cognitive dysfunction

Frontiers in Pharmacology
Postoperative cognitive dysfunction (POCD) is a common and significant neurological complication, occurring more frequently in elderly individuals and those with frailty or underlying neurodegenerative conditions, though it is not limited to these ...
Sha Zhang, Fangeng Meng, Y. Rong, Yi-Wen Zhang, Huaqin Liu   +4 more
semanticscholar   +1 more source

The Glymphatic System and Sleep Dysfunction in Parkinson's Disease.

Sleep Medicine Clinics
Parkinson's disease (PD) is characterized by both motor and nonmotor symptoms, including significant sleep disturbances. The glymphatic system, a brain-wide clearance mechanism active during sleep, may play a key role in PD pathology by impairing the ...
Daniele Urso, V. Gnoni, Eleonora Rollo, Carlo Santoro, W. Jost, G. Logroscino   +5 more
semanticscholar   +1 more source

The Role of the Glymphatic System

The glymphatic system, a recently identified waste clearance pathway in the brain, is crucial for removing waste products and maintaining brain homeostasis. Similar to the lymphatic system in the body, the glymphatic system operates uniquely within the brain.
Gaiqing Wang, Haiyun Chen, Juan Yang, Jing Wang, Bo Yan, Minglei Chen   +5 more
openaire   +1 more source