Results 251 to 260 of about 24,909,638 (279)
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Glymphatic system dysfunction in neurodegenerative diseases
Current Opinion in NeurologyPurpose of review Purpose of this review is to update the ongoing work in the field of glymphatic and neurodegenerative research and to highlight focus areas that are particularly promising. Recent findings Multiple reports have over the past decade documented that glymphatic fluid ...
Beschorner, Natalie, Nedergaard, Maiken
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BMC Medical Imaging
Neonatal brain development constitutes a critical period of structural and functional maturation underpinning sensory, motor, and cognitive capacities. The glymphatic system—a cerebral waste clearance network—remains poorly understood in neonates.
Ting Peng +19 more
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Neonatal brain development constitutes a critical period of structural and functional maturation underpinning sensory, motor, and cognitive capacities. The glymphatic system—a cerebral waste clearance network—remains poorly understood in neonates.
Ting Peng +19 more
semanticscholar +1 more source
Neurodegenerative Diseases
Background: The glymphatic system is a waste clearance system that facilitates the efficient removal of interstitial solutes, including neurotoxic substances such as β-amyloid, from the central nervous system.
Masahiro Ohara, Takaaki Hattori
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Background: The glymphatic system is a waste clearance system that facilitates the efficient removal of interstitial solutes, including neurotoxic substances such as β-amyloid, from the central nervous system.
Masahiro Ohara, Takaaki Hattori
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The glymphatic system and Amyotrophic lateral sclerosis
Progress in NeurobiologyThe glymphatic system and the meningeal lymphatic vessels provide a pathway for transport of solutes and clearance of toxic material from the brain. Of specific relevance to ALS, this is applicable for TDP-43 and glutamate, both major elements in disease pathogenesis.
Eisen, Andrew +3 more
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Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
Objectives: The choroid plexus produces cerebrospinal fluid, which is crucial for glymphatic system function. Evidence suggests that changes in the volume of the choroid plexus may be associated with glymphatic system function.
Ho-Joon Lee, Dong Ah. Lee, K. Park
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Objectives: The choroid plexus produces cerebrospinal fluid, which is crucial for glymphatic system function. Evidence suggests that changes in the volume of the choroid plexus may be associated with glymphatic system function.
Ho-Joon Lee, Dong Ah. Lee, K. Park
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International Journal of Molecular Sciences
Neurodegenerative disorders, including Alzheimer’s disease (AD), are a growing problem in aging society. The amyloid cascade hypothesis has recently been questioned, and therapies based on it have not yielded the expected results.
Kamila Kopeć +2 more
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Neurodegenerative disorders, including Alzheimer’s disease (AD), are a growing problem in aging society. The amyloid cascade hypothesis has recently been questioned, and therapies based on it have not yielded the expected results.
Kamila Kopeć +2 more
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The Glymphatic System and its Relationship to Migraine
Current Neurology and Neuroscience ReportsWe aim to critically review animal and human studies of the glymphatic system in migraine and propose a model for how the glymphatic system may function in migraine, based on the available evidence.Early studies in animal models report migraine attacks temporarily disrupt glymphatic flow. Human imaging studies suggest chronic migraine may be associated
Alana Fretes, Burgos +2 more
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Functional abnormalities of the glymphatic system in cognitive disorders
Neural Regeneration ResearchVarious pathological mechanisms represent distinct therapeutic targets for cognitive disorders, but a balance between clearance and production is essential for maintaining the stability of the brain’s internal environment. Thus, the glymphatic system may
Wuyue Shentu +9 more
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The glymphatic system as a therapeutic target: TMS-induced modulation in older adults
Frontiers in Aging NeuroscienceWhile repetitive transcranial magnetic stimulation (rTMS) is a promising neuromodulatory intervention for cognitive impairment, its effects on the glymphatic system remain unexplored in clinical populations.
M. Sundman +3 more
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Sleep and the glymphatic system
American Nurse JournalUnderstanding how sleep works can aid patient assessments and improve overall care.
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