Results 11 to 20 of about 103 (75)
Russian Open Medical Journal, 2022 Objective — To examine the morphometric parameters of neurons and the oxidative status of the Wistar rat brain tissues after administering proline-containing peptides, also known as glyprolines (Arg-Gly-Arg-Pro-Gly-Pro [RGRPGP] and Thr-Lys-Pro-Arg-Pro ...
Anna A. Kolesnikova +4 more
doaj +1 more source
Glyprolines: Regulatory peptides with an integrative action
Integrative Physiology, 2020 A series of C-substituted N-phenylacetylglycylprolines were synthesized. Their structure-activity (antihypoxic) relationship was studied in normobaric hypoxia tests at i.p. doses of 0.1 – 1 mg/kg as a function of the C-substitution. The amide and ethyl ester of N-phenylacetylglycyl-L-proline exhibited antihypoxic activity and could cyclize in ...
K. N. Kolyasnikova +5 more
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The modern view on the role of glyprolines by metabolic syndrome
Medicinal Research Reviews, 2020 AbstractThe analysis of the literature data and own experimental studies on the effect of glyproline peptides on fat, carbohydrate metabolism, and hemostasis system when modeling metabolic syndrome in animals (rats) was carried out. Violations of fat and carbohydrate metabolism are characterized by hypercoagulation, increased glucose levels ...
Nikolai F, Myasoedov +5 more
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P1663: LYSINE‐CONTAINING OLIGOPEPTIDES CAN INCREASE FIBRINOLYTIC ACTIVITY
, 2023 HemaSphere, Volume 7, Issue S3, August 2023.
Tatiana Shubina +3 more
wiley +1 more source
Сибирский научный медицинский журнал, 2019 Effects of glyproline-containing peptide Selank on oxidative stress parameters in the brain and thin intestine were studied. Material and methods. Traumatic brain injury (TBI) was induced in rats by a shock model (weight drop method).
M. Yu. Fleyshman +2 more
doaj +1 more source
Effect of glyprolines on serum caspase levels under “social” stress
Человек и его здоровье, 2021 Objective. To investigate the effect of glyprolines on the levels of initiating and effector caspases in the serum of white rats under "social" stress. Materials and methods. The study was conducted on 90 white male rats of 6 months of age. All manipulations with animals were carried out in accordance with international and domestic requirements for ...
Anna L. Yasenyavskaya +5 more
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Journal of Diabetes Investigation, Volume 10, Issue 5, Page 1177-1188, September 2019., 2019 The chemical structures of the studied peptides. Abstract Aims/Introduction Peptides are considered to be quasi‐hormones and effective molecules for regulation of the cells function and prevention of metabolic disorders. Di‐ and tripeptides gastrointestinal absorption ability have been proposed to prevent diabetes progression.
Tohid Vahdatpour +5 more
wiley +1 more source
The influence of glyprolins on the behavior of laboratory animals under experimental hyperthyroidism
Bulletin of the Russian Military Medical Academy, 2021 This study aimed to determine the peculiarities of behavioral reactions and psychoemotional status of laboratory animals in experimental hyperthyroidism conditions against the background of introducing peptides of glyproline series (selank and tripeptide Pro-Gly-Pro). All experiments were conducted on white non-linear male rats, which were divided into
Mariyam U. Sergalieva +5 more
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PB2417 SPECTRUM OF HAEMOGLOBINOPATHIES;A TERTIARY CARE HOSPITAL EXPERIENCE
HemaSphere, Volume 3, Issue S1, Page 1073, June 2019., 2019 Background: Inherited abnormalities of hemoglobin synthesis include a myriad of disorders ranging from thalassemia syndromes to structurally abnormal hemoglobin variants. Identification of these disorders is immensely important epidemiologically and aid in prevention of more serious hemoglobin disorders.
N. Fareed, G. Fatima, M. Quraishy
wiley +1 more source
, 2022 Research and Practice in Thrombosis and Haemostasis, Volume 6, Issue S1, October 2022.
wiley +1 more source