Results 191 to 200 of about 332,782 (345)

GM-CSF does not rescue poor-quality embryos: secondary analysis of a randomized controlled trial [PDF]

open access: hybrid, 2020
Kenny A. Rodriguez‐Wallberg   +3 more
openalex   +1 more source

Anti‐Carbamylated Protein Antibodies Stabilize Carbamylated Histone H3 to Promote Synovial Activation and Neutrophil Extracellular Trap‐Mediated Bone Loss in Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Carbamylation, a nonenzymatic post‐translational modification, contributes to rheumatoid arthritis (RA) pathogenesis. Anti‐carbamylated protein antibodies (anti‐CarP) occur in around 50% of patients with RA and associate with greater joint damage. Neutrophil extracellular traps (NETs) are a major source of carbamylated autoantigens. We sought
Shuichiro Nakabo   +9 more
wiley   +1 more source

Pathogenic GM-CSF drives functional diversification of inflammatory macrophages in autoimmune arthritis. [PDF]

open access: yesSci Adv
Mukoyama H   +8 more
europepmc   +1 more source

Kidney Hematopoietic Stem and Progenitor Cells Contribute to Myeloid Development and Pathology in Lupus Nephritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective The hematopoietic system maintains homeostasis by balancing myeloid and lymphoid cell production in the bone marrow (BM). In response to increased hematopoietic demand, extramedullary hematopoiesis (EMH) may occur in nonlymphoid organs. We investigated the role of EMH and kidney‐resident hematopoietic stem and progenitor cells (HSPCs) in ...
Hansol Yi   +9 more
wiley   +1 more source

Tofacitinib repairs inflammation and mitochondrial dysregulation in GM-CSF-reprogrammed RA macrophages. [PDF]

open access: yesCell Mol Immunol
Satoeya N   +17 more
europepmc   +1 more source

T cells, the Next Big Target in Axial Spondyloarthritis?

open access: yesArthritis &Rheumatology, EarlyView.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source

Lipid nanoparticle GM-CSF replacement for autoimmune pulmonary alveolar proteinosis. [PDF]

open access: yesProc Natl Acad Sci U S A
Lian L   +14 more
europepmc   +1 more source

GM-CSF secretion in primary cultures of normal and cancerous human renal cells

open access: bronze, 1996
Nicole D. Stephens   +5 more
openalex   +1 more source

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