Results 121 to 130 of about 19,645 (252)

GM1 ganglioside in Parkinson\u27s disease: Pilot study of effects on dopamine transporter binding. [PDF]

open access: yes, 2015
OBJECTIVE: GM1 ganglioside has been suggested as a treatment for Parkinson\u27s disease (PD), potentially having symptomatic and disease modifying effects.
Brašić, James R.   +7 more
core   +1 more source

Water response to ganglioside GM1 surface remodelling

open access: yesBiochimica et Biophysica Acta (BBA) - General Subjects, 2017
Gangliosides are biological glycolipids participating in rafts, structural and functional domains of cell membranes. Their headgroups are able to assume different conformations when packed on the surface of an aggregate, more lying or standing. Switching between different conformations is possible, and is a collective event.
P. Brocca   +8 more
openaire   +3 more sources

Conduction block in acute motor axonal neuropathy [PDF]

open access: yes, 2017
Guillain-Barré syndrome is divided into two major subtypes, acute inflammatory demyelinating polyneuropathy and acute motor axonal neuropathy. The characteristic electrophysiological features of acute motor axonal neuropathy are reduced amplitude or ...
Hirata, Koichi   +5 more
core  

Altered GM1 catabolism affects NMDAR-mediated Ca2+ signaling at ER-PM junctions and increases synaptic spine formation in a GM1-gangliosidosis model

open access: yesCell Reports
Summary: Endoplasmic reticulum-plasma membrane (ER-PM) junctions mediate Ca2+ flux across neuronal membranes. The properties of these membrane contact sites are defined by their lipid content, but little attention has been given to glycosphingolipids ...
Jason A. Weesner   +9 more
doaj   +1 more source

α/β-Peptides as Nanomolar Triggers of Lipid Raft-Mediated Endocytosis through GM1 Ganglioside Recognition. [PDF]

open access: yesPharmaceutics, 2022
Hetényi A   +11 more
europepmc   +1 more source

GM1 - gangliosidosis in a Nigerian infant: A case report

open access: yesNigerian Journal of Paediatrics, 2021
Gangliosidoses belong to the group of genetic lipid metabolism disorders, caused by defects of lysosome enzymes, inherited as an autosomal recessive trait. Gangliosidosis GM1 is caused by the deficiency of the acid beta galactosidase (GLB11) resulting in
Abdullahi M Sakina   +3 more
doaj  

Autophagy-dependent removal of α-synuclein: a novel mechanism of GM1 ganglioside neuroprotection against Parkinson's disease. [PDF]

open access: yesActa Pharmacol Sin, 2021
Guo YL   +10 more
europepmc   +1 more source

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