Results 141 to 150 of about 101,384 (314)

A Robust Deep Temporal Causal Discovery Platform for Single‐Cell Gene Regulatory Network Reconstruction

open access: yesAdvanced Intelligent Discovery, EarlyView.
scTIGER2.0 is a deep‐learning framework that infers gene regulatory networks from single‐cell RNA sequencing data. By integrating correlation, pseudotime ordering, deep learning and bootstrap‐based significance testing, it reduces false positives and reveals directional gene interactions.
Nishi Gupta   +3 more
wiley   +1 more source

gmp in China [PDF]

open access: yes, 2016
GMP IN CHINA Baunetzwoche (Rights reserved) (-) Ausgabe 451.2016 gmp in China (Rights reserved) (-

core  

Ocular findings in X-linked ichthyosis: A survey on 38 cases

open access: yes, 1991
The authors report on the occurrence of ocular abnormalities in X-linked ichthyosis (XLI) patients, in their carrier mothers and in healthy volunteers who served as controls.
DELFINO, MARIO   +4 more
core   +1 more source

USB1 deficiency disrupts neutrophil maturation via RNA dysregulation independent of global pre‐mRNA splicing

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the essential role of USB1 in neutrophil maturation. In normal myeloid cells, USB1 acts as an RNA exonuclease, trimming RNA tails to maintain proper RNA network function, which supports the differentiation of myeloid progenitor cells into mature neutrophils.
Hang Li   +6 more
wiley   +1 more source

Recent advances in the construction of humanized animal models and applications in translational medicine

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley   +1 more source

Cyclic GMP System in Epidermis: II. Histamine Stimulates Cyclic GMP Formation

open access: yes, 1979
In search of hormones and drugs which might elevate the intracellular level of cyclic GMP in pig epidermis, we have tested the effects of carbachol, concanavalin A, prostaglandin F2α, insulin, epinephrine, Vitamin A acid and histamine. Only histamine was
Adachi, Kenji   +4 more
core   +1 more source

Multifactor Evaluation of Good Manufacturing Practices Implementation on Cuttlefish Products in Cold Storage PPN Brondong, Lamongan

open access: yesGrouper
This study aims to evaluate the main components of Good Manufacturing Practices (GMP) in the processing of cuttlefish products at the Cold Storage facility of PPN Brondong, Lamongan.
Hikmah Farinsyah   +2 more
doaj   +1 more source

PEG Alternatives in Liposomal Nanocarriers: Physicochemical Characteristics and Sustainable Process Strategies

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The global trend toward sustainable and intensified bioprocesses is driving innovation in the design and scalable synthesis of liposomal nanocarriers, a cornerstone of modern drug delivery. For decades, these nanosystems have relied exclusively on polyethylene glycol (PEG) for their sustained circulation in vivo, but they are currently ...
Chandra Has
wiley   +1 more source

Unraveling ovarian histology: The key morphological aspects that spur the development of the Fossa ovarii in equine

open access: yesThe Anatomical Record, EarlyView.
Abstract The equine ovary exhibits unique structural and developmental features that distinguish it from those of other domestic species, including the presence of an ovulation fossa and an inversion of cortical and medullary layers. This study aimed to investigate the morphostructural development of the equine fetal ovary, with particular emphasis on ...
Laura Ver Goltz   +5 more
wiley   +1 more source

Comparative Analysis Of Integer Factorization Algorithms Using Cpu And Gpu

open access: yesMANAS: Journal of Engineering, 2017
In this work we have evaluated the running time of four integer factorization algorithms, namely, trial division algorithm, Fermat algorithm, Pollard rho and Brent algorithms.
Rita Ismailova   +2 more
doaj  

Home - About - Disclaimer - Privacy