Food Safety and Health, EarlyView.In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso +3 more
wiley +1 more source
Assessment of current good manufacturing practice (cGMP) compliance in pharmaceutical manufacturers in Ethiopia: Cross-sectional descriptive study. [PDF]
PLoS OneAdola TB +5 more
europepmc +1 more source
Somatic cell reprogramming for Parkinson's disease treatment
Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
Understanding c-di-GMP-mediated regulation of flagellar motility, one step at a time. [PDF]
J BacteriolO'Toole GA.
europepmc +1 more source
International Journal of Cancer, EarlyView.Chromosomal instability is a hallmark of cancer, but minimally invasive ways to detect systemic DNA damage and cancer risk remain limited. Here, using patient blood samples, the authors investigated lymphocyte micronuclei (MN) frequency as a potential marker of DNA damage across the progression from gastroesophageal reflux disease to Barrett's ...
Kathryn Munn +13 more
wiley +1 more source
3D-Printed Vancomycin-Loaded ZIF-8@GMP Scaffolds with Sustained Antibacterial, Anti-Inflammatory, and Osteoinductive Properties for Bone Tissue Engineering. [PDF]
ACS OmegaZheng J +7 more
europepmc +1 more source
International Journal of Cancer, EarlyView.The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg +9 more
wiley +1 more source
<i>Azotobacter vinelandii</i> AmrZ is a global regulator linking alginate production and c-di-GMP homeostasis. [PDF]
Microbiology (Reading)Gonzaga-Pérez MC +6 more
europepmc +1 more source
The rising tide: Trends in induction of labor at term over a 5‐year period at a single centre
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 383-390, April 2025.Abstract Objective Induction of labor (IOL) is a controversial topic in contemporary obstetric practice, with some suggesting that the increase in elective induction (eIOL) as a potential contributor to increasing cesarean delivery (CD) rates. The objectives of this single‐center study were to examine the rates of IOL, trends in indications for IOL ...
Sarah M. Nicholson +7 more
wiley +1 more source
Ifn1 is an intracellular GMP 5'-nucleotidase induced during the fission yeast response to phosphate starvation. [PDF]
mBioInnokentev A, Schwer B, Shuman S.
europepmc +1 more source