Results 181 to 190 of about 189,721 (306)

Predictive factors for emergency cesarean section in grand multiparous compared to primiparous and multiparous women

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To identify predictive factors for emergency cesarean section (CS) in grand multiparous women and compare them with primiparous and multiparous women. Methods This was a retrospective cohort study in a single large university‐affiliated tertiary medical center between 2011 and 2018, analyzing all women with singleton pregnancies that
Roza Berkovitz Shperling, Liat Lerner‐Geva, Gal Ariel, Inna Zaslavsky Paltiel, Vered H. Eisenberg   +4 more
wiley   +1 more source

Cyclic di-GMP suppresses cancer metastasis by targeting proteasome 26S subunit non-ATPase 3 independently of STING. [PDF]

Signal Transduct Target Ther
Wang J, Mrozek A, Hu K, You H, Traverse SE, Lee H, Zeng SX, Pang X, Park H, Lu H.   +9 more
europepmc   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

In-Situ Exploration of Phytic Acid-Mediated Supramolecular Self-Assembly and Gelation. [PDF]

Anal Chem
Yen YS, Zhang CW, Chuang WT, Chang CF, Hiramatsu H, Hsu HY.   +5 more
europepmc   +1 more source

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

Interdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi, Bei Li, Wanzhu Liu, Haifeng Wu, Wenrong Xu, Cheng Ji, Hui Qian   +6 more
wiley   +1 more source

Engineering exosomal cargo loading via endogenous molecular pathways: Strategies to enhance therapeutic potential

Interdisciplinary Medicine, EarlyView.
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu, Chenning Zhang, Shihan Ma, Zhanxue Xu, Cailing Liang, Fang Cheng, Hongbo Chen   +6 more
wiley   +1 more source

The MarR Family Transcriptional Regulator EmrR Negatively Regulates the Type III Secretion System (T3SS) and Positively Modulates Pathogenicity in Dickeya oryzae. [PDF]

Mol Plant Pathol
Lv M, Huang W, Meng Z, Fan X, Li P, Xu Z, Chen S, Chen X, Zhou J, Zhang L, Cheng Y, Zhuo T, Hu M.   +12 more
europepmc   +1 more source

Cyclic GMP [PDF]

, 2020
openaire   +1 more source

Large‐Scale Evaluation of Traditional Chinese Medicines Reveals Potential PPARγ Modulators for Type 2 Diabetes Management

Journal of Clinical Laboratory Analysis, EarlyView.
Identifying novel treatments for diabetic management is always a competitive research topic all over the world. PPAR‐γ is one of the key regulators involved in glucose and lipid metabolism and improves insulin sensitivity and glucose homeostasis. This study investigated the impacts of 639 traditional Chinese medicine (TCM) on PPAR‐γ gene promoter ...
Mingyuan Dou, Shandra Jones, Juan Montes, Jonathan Ritter, Li‐Yu Shih, Chia‐Jung Chan, Ying‐Chou Lin, Min Chen, Shih‐Yin Chen, Ning Wu   +9 more
wiley   +1 more source

Biofilm engineering through c-di-GMP tuning boosts bioleaching efficiency and arsenic tolerance in <i>Acidithiobacillus ferrooxidans</i>. [PDF]

Appl Environ Microbiol
Han X, Hu Y, Yue Y, Ding Y, Cao B, Shi L, Liu J.   +6 more
europepmc   +1 more source