Results 61 to 70 of about 117,081 (314)

Nanopharmaceutics: Part I—Clinical Trials Legislation and Good Manufacturing Practices (GMP) of Nanotherapeutics in the EU

Pharmaceutics, 2020
The latest advances in pharmaceutical technology are leading to the development of cutting edged approaches to produce what is now known as the “Holy Grail” of medicine—nanopharmaceutics.
Eliana B. Souto, Gabriela F. Silva, João Dias-Ferreira, Aleksandra Zielinska, Fátima Ventura, Alessandra Durazzo, Massimo Lucarini, Ettore Novellino, Antonello Santini   +8 more
doaj   +1 more source

Development of Retraining Systems for the Implementation of the Pharmaceutical Quality System at Pharmaceutical Production Enterprises of the EAEU Countries

Разработка и регистрация лекарственных средств, 2021
Introduction. The publication discusses the state and problems of personnel retraining in the implementation of the pharmaceutical quality system at pharmaceutical enter-prises of the Eurasian Union (EU) countries.Aim.
V. A. Smirnov, V. V. Goryachkin, V. N. Shestakov, R. A. Abramovich   +3 more
doaj   +1 more source

The YfiBNR signal transduction mechanism reveals novel targets for the evolution of persistent Pseudomonas aeruginosa in cystic fibrosis airways [PDF]

, 2012
The genetic adaptation of pathogens in host tissue plays a key role in the establishment of chronic infections. While whole genome sequencing has opened up the analysis of genetic changes occurring during long-term infections, the identification and ...
Tina Jaeger (158216), Jenal Urs, Jacob G. Malone (158210), Blanka Andrea, Pablo Manfredi, Andrea Blanka, Guy R. Cornelis, Jacob G. Malone, Jaeger Tina, Cornelis Guy R., Bos, R., Manfredi, Pablo, Jacob G Malone, Dötsch, A., Jaeger, T., Blanka, A., Pablo Manfredi (158219), Cornelis, Guy R, Manfredi, P., Bos Raphael, Andrea Blanka (158227), Raphael Bos (158229), Jenal, Urs, Jaeger, Tina, Tina Jaeger, Malone, Jacob G., Urs Jenal (37942), Jenal, U., Blanka, Andrea, Malone Jacob G., Dötsch Andreas, Susanne Häussler (158235), Urs Jenal, Häussler, S., Andreas Dötsch, Cornelis, Guy R., Susanne Häussler, Häussler, Susanne, Manfredi Pablo, Häussler Susanne, Raphael Bos, Guy R. Cornelis (158232), Guy R Cornelis, Malone, Jacob G, Dötsch, Andreas, Cornelis, G. R., Andreas Dötsch (158223), Bos, Raphael, Malone, J. G., Bos R, Cornelis GR, Jenal U, Malone JG, Manfredi P, Jaeger T, Dötsch A, Blanka A, Häussler S   +57 more
core   +1 more source

UC Food Waste: A Multimodal Robotic Perception Dataset for Robust Contaminant Detection in Complex Biowaste Scenes

Advanced Robotics Research, EarlyView.
A balanced multimodal food‐waste dataset and a novel Split Spatial‐Spectral Attention fusion framework are presented for robotic contaminant detection. Separate processing of RGB, thermal, and multispectral inputs preserves subtle material signatures before feature integration, reducing modality interference and improving classification and ...
Matthew Vestal, James Ireland, David Hinwood, Xing Wang, Min Wang, Damith Herath   +5 more
wiley   +1 more source

PROBLEMS OF CONFORMITY OF THE RECORDS INTEGRITY WITH THE REQUIREMENTS OF GOOD MANUFACTURING PRACTICE. REPORT 1. ACTUALITY OF THE RECORDS INTEGRITY CONSERVATION

Разработка и регистрация лекарственных средств, 2019
Integrity of records or data integrity is the most «hot» requirement when assessing documentation systems for compliance with Good Manufacturing Practice (GMP). It's in the center of focus of attention during inspections of pharmaceutical companies. This
I. A. Osmolovskaya, O. V. Zarochinskaya, M. O. Emelianov, D. V. Somov   +3 more
doaj  

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

Advanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin, Saurabh Singh, Soumya Chatterjee, Guang‐Zhi Sui, Yi‐Fu Wang, Ya‐Ting Lu, Yu‐Ling Lee, Kun‐Yuan Lin, Joy Khag, Ta‐Yu Liu, Shao‐Han Chang, Wai‐Mui Cheung, Hsiao‐Chin Hong, Ren‐Jun Hsu, Chen‐Yang Shen, Chia‐Wei Li, Weng‐Lang Yang, Yao‐Ming Chang, Shih‐Yu Chen, Chandan Guha, Shu‐Ping Wang   +20 more
wiley   +1 more source

Overview of the validation procedures for a vaccine production: from R;D level to the pre-qualification stage

Vaccine Research, 2015
Just like any other process, vaccine manufacturing procedures are defined as a series of interrelated functions and activities using a variety of specified actions and equipment designed to produce a defined product.
H Kaghazian, D Doroud
doaj  

Analisis HACCP Pada UKM Minuman Siap Saji Aloe Vera (ALOJA) Sebagai Sarana Memenuhi Standar Produksi Pangan Yang Baik

Amerta Nutrition, 2020
Background: BPOM stated that in 2017, small and micro food enterprises were responsible for 49,5 % food borne disease in Indonesia. Indonesian government had provided guidance about good handling standard for food product (GMP) by UU No.18 Tahun 2012 ...
Dimas Bayu Pinandoyo, Asriadi Masnar
doaj   +1 more source

The rate and variability of curli induction for the wild-type and for the c-di-GMP-regulation disabled strain.

, 2023
(A) Median curli expression, (B) production rate, and (C) number of cells for traces from both microfluidics experiments (r1 and r2) aligned by the time at which they exceeded a threshold of 103 fluorescence units.
Victor Sourjik (195604), Olga Lamprecht (15470899), Paulina Jacek (15470905), Nina Buettner (15470908), Ina Biazruchka (15470914), Julian Pietsch (15470920), Eugen Kaganovitch (5642255), Kirstin Fritz (15470911), Maryia Ratnikava (15470902), Robin Köhler (15470917)   +9 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source