Results 51 to 60 of about 51,102 (238)
Galaxy chemical evolution models: The role of molecular gas formation [PDF]
, 2017 In our classical grid of multiphase chemical evolution models, star formation in the disc occurs in two steps: first, molecular gas forms, and then stars are created by cloud-cloud collisions or interactions of massive stars with the surrounding ...
Ascasibar, Yago +4 more
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GNE Myopathy With Novel Mutations and Pronounced Paraspinal Muscle Atrophy
Frontiers in Neurology, 2018 GNE myopathy is characterized by distal muscle weakness, and caused by recessive mutations in GNE. Its onset is characteristically in young adulthood, although a broad spectrum of onset age is known to exist.
Tyler Soule +7 more
doaj +1 more source
Myogenesis defects in a patient-derived iPSC model of hereditary GNE myopathy
npj Regenerative Medicine, 2022 Hereditary muscle diseases are disabling disorders lacking effective treatments. UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE) myopathy (GNEM) is an autosomal recessive distal myopathy with rimmed vacuoles typically manifesting in ...
Rebecca E. Schmitt +8 more
doaj +1 more source
Advancement of scienceGlioblastoma (GBM) resistance to chemoradiotherapy is a major factor contributing to poor treatment outcomes. This resistance markedly affects the effectiveness of surgery combined with chemoradiotherapy and leads to post‐surgical tumor recurrence ...
Yong-Chang Yang +15 more
semanticscholar +1 more source
Phase II/III Study of Aceneuramic Acid Administration for GNE Myopathy in Japan
Journal of Neuromuscular Diseases, 2023 Background: GNE myopathy is an ultra-rare muscle disease characterized by a reduction in the synthesis of sialic acid derived from pathogenic variants in the GNE gene. No treatment has been established so far.
N. Suzuki +17 more
semanticscholar +1 more source
Electromagnetic Form Factors of the Nucleon [PDF]
, 1997 We reanalyze the world data on the electromagnetic form factors of the nucleon. The calculations are performed in the framework of an algebraic model of the nucleon combined with vector meson dominance.Comment: 5 pages with 6 figures and aipproc.sty file,
Bijker, R., Leviatan, A.
core +2 more sources
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023 GNE myopathy, caused by biallelic mutations in the GNE gene, is characterized by initial ankle dorsiflexor weakness and rimmed vacuoles in the muscle histopathology, resulting in reduced sialic acid production.
Young-Eun Park +8 more
semanticscholar +1 more source
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023 UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) myopathy is an autosomal recessive disease characterized by rimmed vacuoles (RVs). Previous studies have shown that metformin protects against several neuromuscular disorders.
Tongtong Zhang +5 more
semanticscholar +1 more source
Efficacy confirmation study of aceneuramic acid administration for GNE myopathy in Japan
Orphanet Journal of Rare Diseases, 2023 Background A rare muscle disease, GNE myopathy is caused by mutations in the GNE gene involved in sialic acid biosynthesis. Our recent phase II/III study has indicated that oral administration of aceneuramic acid to patients slows disease progression ...
M. Mori-Yoshimura +17 more
semanticscholar +1 more source
Dust in the diffuse emission of the galactic plane - The Herschel/Spitzer SED fitting [PDF]
, 2010 The first Herschel Hi-Gal images of the galactic plane unveil the far-infrared diffuse emission of the interstellar medium with an unprecedented angular resolution and sensitivity. In this paper, we present the first analysis of these data in combination
Compiègne +7 more
core +2 more sources