Results 221 to 230 of about 352,015 (307)

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Osimertinib activates a TGF-β2-dependent secretory program that drives lung adenocarcinoma progression. [PDF]

J Clin Invest
Ghosh M, Wu C, Kumar A, Nilsson M, Heymach JV, Zhao W, Yu J, Liu X, Ding N, Wang S, Xiao GY, Chen A, Grimley K, Russell WK, Creighton CJ, Tan X, Kurie JM.   +16 more
europepmc   +1 more source

Golgi Apparatus [PDF]

, 2020
openaire   +1 more source

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

Corrigendum to A CLN6-CLN8 complex recruits lysosomal enzymes at the ER for Golgi transfer. [PDF]

J Clin Invest
Bajaj L, Sharma J, di Ronza A, Zhang P, Eblimit A, Pal R, Roman D, Collette JR, Booth C, Chang KT, Sifers RN, Jung SY, Weimer JM, Chen R, Schekman RW, Sardiello M.   +15 more
europepmc   +1 more source

Isolation and characterization of a functionally active protein translocation apparatus from chloroplasts envelopes [PDF]

, 1993
Morré, D. James, Soll, Jürgen, Waegemann, Karin   +2 more
core  

Proteomic Profiling of Alveolar Macrophages Identifies Loss of Lysosomal Content as an Indicator of Nanofiber‐Induced Frustrated Phagocytosis

Small, EarlyView.
This proteomic study examines how nanofibers affect lung macrophages by analyzing protein changes following exposure to various fibrous materials. Nanofibers triggered the release of inflammatory enzymes, and importantly, lysosomal content release was identified as an early event associated with frustrated phagocytosis. Seventeen sensitive and relevant
Tobias Stobernack, Antje Vennemann, Carla Ribalta, Julia Schendel, Oliver Gräb, Rico Ledwith, Mario Pink, Andrea Haase, Martin Wiemann, Verónica I. Dumit   +9 more
wiley   +1 more source

Quantitative Modeling of IgG N-Glycosylation Profiles from Population Data. [PDF]

Int J Mol Sci
Kutumova E, Mandrik N, Sharipov R, Pučić-Baković M, Rapčan B, Aulchenko Y, Lauc G, Kolpakov F.   +7 more
europepmc   +1 more source

Nanobody–chlorin e6 conjugate for Nectin‐4‐mediated tumor targeting and enhanced photodynamic therapy

VIEW, EarlyView.
Nectin‐4 is frequently overexpressed in solid tumors, yet many PDT photosensitizers show poor water solubility and nonspecific uptake. A Nectin‐4‐targeted nanobody–chlorin e6 conjugate (NPC) improves aqueous solubility and selectively accumulates in Nectin‐4‐positive tumor cells.
Haodian Wan, Tao Ye, Yawei Bi, Jiayu Zhang, Wei Wu, Aochi Liu, Li Sun, Jie Lin, Ningli Chai, Manjie Zhang, Jian Ma   +10 more
wiley   +1 more source

Organelle stress in NLRP3 inflammasome: a central mediator of neurodegenerative diseases. [PDF]

Mol Neurodegener
Jia H, Ma L, Liu J, Gao M, Liang X, Zhang F, Gao Y, Liu M, Jiang W, Wei M, Zhong X.   +10 more
europepmc   +1 more source