Results 41 to 50 of about 352,015 (307)
Current Biology, 2000 Farquhar MG, Palade GE: The Golgi apparatus: 100 years of progress and controversy.Trends Cell Biol 1998, 8:2-10.Nelson WJ: W(h)ither the Golgi during mitosis?J Cell Biol 2000, 149:243-248.Palade GE: Intracellular aspects of the process of protein secretion.Science 1975, 189:347-388.Rothman JE, Wieland FT: Protein sorting by transport vesicles.Science ...
Short, Ben, Barr, Francis A.
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The MX-Helix of Muscle nAChR Subunits Regulates Receptor Assembly and Surface Trafficking. [PDF]
, 2020 Nicotinic acetylcholine receptors (AChRs) are pentameric channels that mediate fast transmission at the neuromuscular junction (NMJ) and defects in receptor expression underlie neuromuscular disorders such as myasthenia gravis and congenital myasthenic ...
Borges, Lucia Soares +3 more
core
Acid sphingomyelinase regulates the localization and trafficking of palmitoylated proteins
Biology Open, 2019 In human, loss of acid sphingomyelinase (ASM/SMPD1) causes Niemann–Pick disease, type A. ASM hydrolyzes sphingomyelins to produce ceramides but protein targets of ASM remain largely unclear. Our mass spectrometry-based proteomic analyses have identified >
Xiahui Xiong +7 more
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Electrochemical Organic Synthesis of Electron-Rich Biaryl Scaffolds: An Update
Molecules, 2021 Biaryl scaffolds are widely spread in biologically important natural products, in numerous therapeutic agents, but they are also considered a privileged class of ligands and (organo)catalysts; therefore, the development of efficient alternative ...
Fabrizio Medici +5 more
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Characterization of a Novel GPI-anchored Protein, a Component of Sphingomyelin-enriched Microdomains at the Golgi Complex [PDF]
, 2003 The Golgi complex is the central station along the secretory pathway to sort proteins and lipids to their final destinations. It exists of a series of flattened cisternal membranes that are aligned in parallel to form polarized stacks.
Li, Xue-Yi
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
ERK8 is a negative regulator of O-GalNAc glycosylation and cell migration
eLife, 2014 ER O-glycosylation can be induced through relocalisation GalNAc-Transferases from the Golgi. This process markedly stimulates cell migration and is constitutively activated in more than 60% of breast carcinomas.
Joanne Chia +4 more
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Actin Cytoskeleton and Golgi Involvement in Barley stripe mosaic virus Movement and Cell Wall Localization of Triple Gene Block Proteins. [PDF]
, 2013 Barley stripe mosaic virus (BSMV) induces massive actin filament thickening at the infection front of infected Nicotiana benthamiana leaves. To determine the mechanisms leading to actin remodeling, fluorescent protein fusions of the BSMV triple gene ...
Bae, Hanhong +10 more
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Cell, 2014 The Golgi apparatus consists of disc-like cisternae, stretching around the nucleus through forces exerted by F-actin and the Golgi membrane protein GOLPH3. Farber-Katz et al. now report that DNA damage triggers Golgi dispersal and inhibits vesicular transport through DNA-PK-mediated GOLPH3 phosphorylation, thereby linking the DNA damage response to ...
M. Foiani, J. Bartek
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An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
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