Results 51 to 60 of about 228,960 (304)
A bioactive peptide amidating enzyme is required for ciliogenesis
eLife, 2017 The pathways controlling cilium biogenesis in different cell types have not been fully elucidated. We recently identified peptidylglycine α-amidating monooxygenase (PAM), an enzyme required for generating amidated bioactive signaling peptides, in ...
Dhivya Kumar +7 more
doaj +1 more source
Mutant huntingtin impairs the post-Golgi trafficking of brain-derived neurotrophic factor but not its Val66Met polymorphism. [PDF]
, 2013 Brain-derived neurotrophic factor (BDNF) polymorphism is associated with the pathophysiology of several neurodegenerative disorders, including Huntington"s disease.
Toro Ruiz, Daniel del +5 more
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Development of neurons in the ectostriatum of normal and monocularly deprived zebra finches: a quantitative Golgi study [PDF]
, 1988 Herrmann K, Bischof H-J. Development of neurons in the ectostriatum of normal and monocularly deprived zebra finches: a quantitative Golgi study. The Journal of Comparative Neurology.
Herrmann, Kathrin +3 more
core +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Evidence for Golgi bodies in proposed 'Golgi-lacking' lineages [PDF]
Proceedings of the Royal Society of London. Series B: Biological Sciences, 2003 Golgi bodies are nearly ubiquitous in eukaryotic cells. The apparent lack of such structures in certain eukaryotic lineages might be taken to mean that these protists evolved prior to the acquisition of the Golgi, and it raises questions of how these organisms function in the absence of this crucial organelle.
Joel B, Dacks +5 more
openaire +2 more sources
The Prion-like domain in the exomer-dependent cargo Pin2 serves as a trans-Golgi retention motif [PDF]
, 2014 Prion and prion-like domains (PLDs) are found in many proteins throughout the animal kingdom. We found that the PLD in the S. cerevisiae exomer-depen- dent cargo protein Pin2 is involved in the regulation of protein transport and localization. The domain
Ritz, Alicja M. +11 more
core +1 more source
The Golgi Apparatus with the Historical Point of View [PDF]
, 2021 Scientists were introduced to the Golgi apparatus (GA) in 1898, when it was discovered by Camillo Golgi in 1898 as a “cytoplasmic reticular network”. Researchers heard Camillo Golgi’s name not only because of the GA, but also because of many definitions ...
Mukaddes EŞREFOĞLU
core +1 more source
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Center of Golgi cisternae at higher magnification [Secretory pathway; 6f]
, 2011 Presents details of the Golgi matrix and tethered transport vesicles are revealed. Clathrin coated buds are readily apparent on the trans-most cisternae and post-Golgi compartments.
McIntosh, J. Richard +2 more
core +2 more sources