Results 61 to 70 of about 75,593 (176)

Geldanamycin Enhances Retrograde Transport of Shiga Toxin in HEp-2 Cells. [PDF]

open access: yesPLoS ONE, 2015
The heat shock protein 90 (Hsp90) inhibitor geldanamycin (GA) has been shown to alter endosomal sorting, diverting cargo destined for the recycling pathway into the lysosomal pathway. Here we investigated whether GA also affects the sorting of cargo into
Anne Berit Dyve Lingelem   +4 more
doaj   +1 more source

Golgi proteins in circulating human platelets are distributed across non-stacked, scattered structures

open access: yesPlatelets, 2017
Platelets are small, anucleate cell fragments that are central to hemostasis, thrombosis, and inflammation. They are derived from megakaryocytes from which they inherit their organelles.
Shilpi Yadav   +6 more
doaj   +1 more source

The Golgi apparatus is a primary site of intracellular damage after photosensitization with Rose Bengal acetate

open access: yesEuropean Journal of Histochemistry, 2009
The aim of the present investigation was to elucidate whether the Golgi apparatus undergoes photodamage following administration of the fluorogenic substrates Rose Bengal acetate (RBAc) and irradiation at the appropriate wavelength. Human HeLa cells were
C Soldani   +5 more
doaj   +1 more source

Deciphering the sub-Golgi localization of glycosyltransferases via 3D super-resolution imaging

open access: yesCell Structure and Function
The Golgi apparatus, a crucial organelle involved in protein processing, including glycosylation, exhibits complex sub-structures, i.e., cis-, medial, and trans-cisternae.
Hirokazu Yagi   +11 more
doaj   +1 more source

Parametric FEM for Shape Optimization applied to Golgi Stack [PDF]

open access: yesarXiv, 2019
The thesis is about an application of the shape optimization to the morphological evolution of Golgi stack. Golgi stack consists of multiple layers of cisternae. It is an organelle in the biological cells. Inspired by the Helfrich Model \cite{Helfrich}, which is a model for vesicles typically applied to biological cells, a new model specially designed ...
arxiv  

The key target of neuroprotection after the onset of ischemic stroke: secretory pathway Ca 2+ -ATPase 1

open access: yesNeural Regeneration Research, 2015
The regulatory mechanisms of cytoplasmic Ca 2+ after myocardial infarction-induced Ca 2+ overload involve secretory pathway Ca 2+ -ATPase 1 and the Golgi apparatus and are well understood.
Li-hua Li, Xiang-rong Tian, Zhi-ping Hu
doaj   +1 more source

Subcellular localization of microsomal triglyceride transfer protein

open access: yesJournal of Lipid Research, 2003
Microsomal triglyceride transfer protein (MTP) is essential for the assembly of apolipoprotein B-containing lipoproteins. Within the endoplasmic reticulum, it transfers lipid from the membrane to the forming lipoprotein.
Larry L. Swift   +8 more
doaj  

Nonequilibrium mechanisms underlying de novo biogenesis of Golgi cisternae [PDF]

open access: yesarXiv, 2016
A central issue in cell biology is the physico-chemical basis of organelle biogenesis in intracellular trafficking pathways, its most impressive manifestation being the biogenesis of Golgi cisternae. At a basic level, such morphologically and chemically distinct compartments should arise from an interplay between the molecular transport and chemical ...
arxiv  

The Cerebellum: New Computational Model that Reveals its Primary Function to Calculate Multibody Dynamics Conform to Lagrange-Euler Formulation [PDF]

open access: yesIJCSI International Journal of Computer Science Issues, Vol. 10, Issue 5, No 2, September 2013, 2014
Cerebellum is part of the brain that occupies only 10% of the brain volume, but it contains about 80% of total number of brain neurons. New cerebellar function model is developed that sets cerebellar circuits in context of multibody dynamics model computations, as important step in controlling balance and movement coordination, functions performed by ...
arxiv  

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