Results 61 to 70 of about 956,222 (367)

Loss of Arabidopsis β-COP Function Affects Golgi Structure, Plant Growth and Tolerance to Salt Stress

Frontiers in Plant Science, 2020
The early secretory pathway involves bidirectional transport between the endoplasmic reticulum (ER) and the Golgi apparatus and is mediated by coat protein complex I (COPI)-coated and coat protein complex II (COPII)-coated vesicles.
Judit Sánchez-Simarro, César Bernat-Silvestre, Fátima Gimeno-Ferrer, Pilar Selvi-Martínez, Javier Montero-Pau, Fernando Aniento, María Jesús Marcote   +6 more
doaj   +1 more source

Non-canonical features of the Golgi apparatus in bipolar epithelial neural stem cells

Scientific Reports, 2016
Apical radial glia (aRG), the stem cells in developing neocortex, are unique bipolar epithelial cells, extending an apical process to the ventricle and a basal process to the basal lamina.
E. Taverna, Felipe Mora-Bermúdez, P. Strzyz, Marta Florio, J. Icha, Christiane Haffner, Caren Norden, Michaela Wilsch-Bräuninger, W. Huttner   +8 more
semanticscholar   +1 more source

Fluid-membrane tethers: minimal surfaces and elastic boundary layers [PDF]

, 2002
Thin cylindrical tethers are common lipid bilayer membrane structures, arising in situations ranging from micromanipulation experiments on artificial vesicles to the dynamic structure of the Golgi apparatus. We study the shape and formation of a tether in terms of the classical soap-film problem, which is applied to the case of a membrane disk under ...
arxiv   +1 more source

Three-dimensional shape of the Golgi apparatus in different cell types: serial section scanning electron microscopy of the osmium-impregnated Golgi apparatus.

Microscopy, 2016
Although many studies of the Golgi apparatus structure have been performed by light and electron microscopy, the full shape of the Golgi apparatus remained unclear due to the technical limitations of the previously applied microscopy techniques.
D. Koga, S. Kusumi, T. Ushiki
semanticscholar   +1 more source

RNAi screening reveals a large signaling network controlling the Golgi apparatus in human cells

Molecular Systems Biology, 2012
The Golgi apparatus has many important physiological functions, including sorting of secretory cargo and biosynthesis of complex glycans. These functions depend on the intricate and compartmentalized organization of the Golgi apparatus.
Joanne Chia, Germaine Goh, Victor Racine, Susanne Ng, Pankaj Kumar, Frederic Bard   +5 more
doaj   +1 more source

PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatus

Nature Communications, 2015
Cholesterol biosynthesis is regulated by transcription factors SREBPs and their escort protein Scap. On sterol depletion, Scap/SREBP complex is transported from endoplasmic reticulum (ER) to the Golgi apparatus where SREBP is activated. Under cholesterol
Daqian Xu, Z. Wang, Yuxue Zhang, Wei Jiang, Yi Pan, B. Song, Yan Chen   +6 more
semanticscholar   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

The neuronal Golgi in neural circuit formation and reorganization

Frontiers in Neural Circuits
The Golgi apparatus is a central hub in the intracellular secretory pathway. By positioning in the specific intracellular region and transporting materials to spatially restricted compartments, the Golgi apparatus contributes to the cell polarity ...
Naoki Nakagawa, Naoki Nakagawa
doaj   +1 more source

ALS/FTD-associated mutation in cyclin F inhibits ER-Golgi trafficking, inducing ER stress, ERAD and Golgi fragmentation

Scientific Reports, 2023
Amyotrophic lateral sclerosis (ALS) is a severely debilitating neurodegenerative condition that is part of the same disease spectrum as frontotemporal dementia (FTD).
Audrey M. G. Ragagnin, Vinod Sundaramoorthy, Fabiha Farzana, Shashi Gautam, Sayanthooran Saravanabavan, Zeinab Takalloo, Prachi Mehta, Dzung Do-Ha, Sonam Parakh, Sina Shadfar, Julie Hunter, Marta Vidal, Cyril J. Jagaraj, Mariana Brocardo, Anna Konopka, Shu Yang, Stephanie L. Rayner, Kelly L. Williams, Ian P. Blair, Roger S. Chung, Albert Lee, Lezanne Ooi, Julie D. Atkin   +22 more
doaj   +1 more source

An Age-dependent Feedback Control Model for Calcium and Reactive Oxygen Species in Yeast Cells [PDF]

arXiv, 2022
Calcium and reactive oxygen species (ROS) interact with each other and play an important role in cell signaling networks. Based on the existing mathematical models, we develop an age-dependent feedback control model to simulate the interaction. The model consists of three subsystems: cytosolic calcium dynamics, ROS generation from the respiratory chain
arxiv