High GOLPH3 expression is associated with poor prognosis and invasion of hepatocellular carcinoma
Molecular Medicine Reports, 2015 Golgi phosphoprotein 3 (GOLPH3) overexpression has previously been associated with the progression of several solid tumors, which resulted in adverse clinical outcomes. The present study aimed to determine the expression and prognostic significance of GOLPH3 in human hepatocellular carcinoma (HCC).
Qian, Li, Yuwen, Ma, Wanpeng, Xu
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Journal of Experimental & Clinical Cancer Research, 2018 Background Serine/threonine protein kinase 25 (STK25) is critical in regulating whole-body glucose and insulin homeostasis and the accumulation of ectopic lipids.
Fan Wu +7 more
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Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration [PDF]
, 2017 Mutations in the vacuolar protein sorting 35 homolog (VPS35) gene at the PARK17 locus, encoding a key component of the retromer complex, were recently identified as a new cause of late-onset, autosomal dominant Parkinson's disease (PD).
Bandopadhyay, Rina +11 more
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Inhibition of NLRP3 and Golph3 ameliorates diabetes-induced neuroinflammation in vitro and in vivo [PDF]
, 2022 Yuan Li +5 more
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Effect of LINC00657 on Apoptosis of Breast Cancer Cells by Regulating miR-590-3p
Cancer Management and Research, 2020 Qiuli Shan,1 Fan Qu,1 Weiping Yang,2 Ningning Chen1 1College of Biological Science and Technology, University of Jinan, Jinan 250022, People’s Republic of China; 2Department of Thyroid Breast Surgery, Qingdao Chengyang People’s Hospital ...
Shan Q, Qu F, Yang W, Chen N
doaj
Molecular Regulation and Physiological Role of GOLPH3-mediated Golgi retention
AbstractThe Golgi complex serves as the central hub of the biosynthetic pathway, where anterograde and retrograde trafficking converge. How cargo and Golgi-resident proteins traverse this organelle has long been debated. Recent studies have identified a molecular machinery that sorts resident proteins into retrograde-directed COPI vesicles during ...
Anastasia Theodoropoulou +26 more
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Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene [PDF]
, 2013 et al,, Strunk, Robert C
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Genetic dissection of meiotic cytokinesis in Drosophila melanogaster males [PDF]
, 2013 Studies in a variety of organisms indicate that membrane traffic to the cleavage furrow is an essential facet of cytokinesis involving components of the secretory and endocytic/recycling trafficking pathways, as well as the membrane fusion machinery ...
SECHI, STEFANO
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The Great Escape: how phosphatidylinositol 4-kinases and PI4P promote vesicle exit from the Golgi (and drive cancer) [PDF]
, 2019 Phosphatidylinositol 4-phosphate (PI4P) is a membrane glycerophospholipid and a major regulator of the characteristic appearance of the Golgi complex as well as its vesicular trafficking, signalling and metabolic functions. Phosphatidylinositol 4-kinases,
Waugh, MG
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