Results 101 to 110 of about 2,136 (186)
European review for medical and pharmacological sciences, 2020 The purpose of this study was to investigate GOLPH3 expression in nasopharyngeal carcinoma (NPC) and its influence on the metastatic ability of NPC cells; meanwhile, the underlying mechanism of GOLPH3 promoting the malignant progression of NPC was also explored.In this study, quantitative Real Time-Polymerase Chain Reaction (qRT-PCR) was performed to ...
Wang, D.-Y., Wang, J., Deng, D.
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Exploring Punicalagin Potential Against Cancers: A Comprehensive Review
Food Science &Nutrition, Volume 13, Issue 3, March 2025.This paper focuses on highlighting the therapeutic potential of punicalagin against tumors and cancers. Punicalagin inhibits tumor growth within the body through various cellular pathway interactions. This compound has efficacy in eliminating tumor cells from the liver, stomach, prostate, and lungs.
Muhammad Hammad Ul Hassan +12 more
wiley +1 more source
Lentivirus Mediated GOLPH3 shRNA Inhibits Growth and Metastasis of Esophageal Squamous Cancer
Asian Pacific Journal of Cancer Prevention, 2013 To investigate the role of Golgi phosphoprotein 3 (GOLPH3) in tumour growth and metastasis of esophageal squamous cancer.A lentiviral shRNA-vector was utilized to stably knockdown GOLPH3 in Eca-109 esophageal squamous cancer cells. mRNA transcription and protein expression of GOLPH3 were examined by real-time quantitative PCR and Western blotting ...
Qiang, Wang, Xian, Wang, Can-Bin, Zhang
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Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration [PDF]
, 2017 Mutations in the vacuolar protein sorting 35 homolog (VPS35) gene at the PARK17 locus, encoding a key component of the retromer complex, were recently identified as a new cause of late-onset, autosomal dominant Parkinson's disease (PD).
Bandopadhyay, Rina +11 more
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Zhongguo shiyan zhenduanxue, 2022 目的 探讨高尔基体磷酸化蛋白3（GOLPH3）、血管内皮生长因子（VEGF）在胃癌组织中的表达情况及其临床意义。方法 选取2018年2月—2019年3月于河北北方学院附属第一医院行胃癌根治性切除手术的103例患者作为研究对象，分析所选患者的临床资料，收集其胃癌组织及癌旁组织。比较不同TNM分期、浸润深度、分化程度、淋巴结转移胃癌患者GOLPH3、VEGF表达情况。结果胃癌组织GOLPH3、VEGF阳性表达率分别为66.02%、58.25%，均高于癌旁组织的19.42%、23.30%（P＜0.05 ...
王锐 +6 more
doaj
COG7 deficiency in Drosophila generates multifaceted developmental, behavioral and protein glycosylation phenotypes [PDF]
, 2017 Congenital disorders of glycosylation (CDG) comprise a family of human multisystemic diseases caused by recessive mutations in genes required for protein N-glycosylation.
Belloni, G. +10 more
core +1 more source
High GOLPH3 expression is associated with poor prognosis and invasion of hepatocellular carcinoma
Molecular Medicine Reports, 2015 Golgi phosphoprotein 3 (GOLPH3) overexpression has previously been associated with the progression of several solid tumors, which resulted in adverse clinical outcomes. The present study aimed to determine the expression and prognostic significance of GOLPH3 in human hepatocellular carcinoma (HCC).
Qian, Li, Yuwen, Ma, Wanpeng, Xu
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Golgi Oncoprotein GOLPH3 Gene Expression is Regulated by Functional E2F and CREB/ATF Promoter Elements [PDF]
, 2019 The Golgi organelle duplicates its protein and lipid content to segregate evenly between two daughter cells after mitosis. However, how Golgi biogenesis is regulated during interphase remains largely unknown.
Field, Seth J. +6 more
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Journal of Experimental & Clinical Cancer Research, 2018 Background Serine/threonine protein kinase 25 (STK25) is critical in regulating whole-body glucose and insulin homeostasis and the accumulation of ectopic lipids.
Fan Wu +7 more
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Overexpression of GOLPH3 is associated with poor survival in non-small-cell lung cancer [PDF]
, 2016 As a highly conserved protein of the Golgi apparatus, Golgi phosphoprotein 3 (GOLPH3) has been shown to be involved in tumorigenesis. This study aims to explore the expression and significance of GOLPH3 in non-small-cell lung cancer (NSCLC).
Chen, D +10 more
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