Results 111 to 120 of about 2,136 (186)

Effect of LINC00657 on Apoptosis of Breast Cancer Cells by Regulating miR-590-3p

open access: yesCancer Management and Research, 2020
Qiuli Shan,1 Fan Qu,1 Weiping Yang,2 Ningning Chen1 1College of Biological Science and Technology, University of Jinan, Jinan 250022, People’s Republic of China; 2Department of Thyroid Breast Surgery, Qingdao Chengyang People’s Hospital ...
Shan Q, Qu F, Yang W, Chen N
doaj  

Molecular Regulation and Physiological Role of GOLPH3-mediated Golgi retention

open access: yes
AbstractThe Golgi complex serves as the central hub of the biosynthetic pathway, where anterograde and retrograde trafficking converge. How cargo and Golgi-resident proteins traverse this organelle has long been debated. Recent studies have identified a molecular machinery that sorts resident proteins into retrograde-directed COPI vesicles during ...
Anastasia Theodoropoulou   +26 more
openaire   +1 more source

Korduva raseduse katkemise genoomsed ja geneetilised riskitegurid [PDF]

open access: yes, 2014
Väitekirja elektrooniline versioon ei sisalda publikatsioone.Spontaanne ehk iseeneslik raseduse katkemine on kõige sagedasem rasedustüsistus. Ligi 3%-l viljakas eas paaridel leiab spontaanabort aset järjestikku kolm või enam korda, mille puhul ...
Nagirnaja, Liina
core  

The Great Escape: how phosphatidylinositol 4-kinases and PI4P promote vesicle exit from the Golgi (and drive cancer) [PDF]

open access: yes, 2019
Phosphatidylinositol 4-phosphate (PI4P) is a membrane glycerophospholipid and a major regulator of the characteristic appearance of the Golgi complex as well as its vesicular trafficking, signalling and metabolic functions. Phosphatidylinositol 4-kinases,
Waugh, MG
core  

Genetic dissection of meiotic cytokinesis in Drosophila melanogaster males [PDF]

open access: yes, 2013
Studies in a variety of organisms indicate that membrane traffic to the cleavage furrow is an essential facet of cytokinesis involving components of the secretory and endocytic/recycling trafficking pathways, as well as the membrane fusion machinery ...
SECHI, STEFANO
core  

GOLPH3 promotes glioma progression by enhancing PHB2-mediated autophagy.

open access: yesAmerican journal of cancer research
Due to the hypoxia and nutrient deficiency microenvironment, malignant glioma exhibits high autophagy activity and autophagy plays a significant role in the occurrence and development of glioma. However, the potential molecular mechanism of autophagy in glioma remains unknown. In this study, we demonstrated that Golgi phosphorylation protein 3 (GOLPH3),
Kai, Wang   +9 more
openaire   +1 more source

Antibodies Directed against the Extracellular Region of the Epidermal Growth Factor Receptor Adopt Distinct Modes of Binding and Inhibition [PDF]

open access: yes, 2010
The work described in this dissertation comprises two distinct projects. In the first, we describe the structural and functional characterization of a family of Golgi associated cytosolic proteins, represented by Vps74 in fungi and GOLPH3 in animals ...
Schmitz, Karl R
core   +1 more source

miR-186 inhibits cell proliferation of prostate cancer by targeting GOLPH3.

open access: yesAmerican journal of cancer research, 2016
Prostate cancer is one of the leading causes of cancer deaths among men, many miRNAs have been demonstrated to play critical role in the progression of prostate cancer, miR-186 suppresses the progression of many tumors, such as bladder cancer and glioma.
Xing, Hua   +7 more
openaire   +1 more source

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