Results 121 to 130 of about 2,136 (186)

Small cell ovarian carcinoma: genomic stability and responsiveness to therapeutics [PDF]

, 2013

core   +1 more source

In silico identification of alkaloids and repurposed drugs as potential small-molecule inhibitors of GOLPH3 in cancer using molecular docking, molecular dynamics, and MM-PBSA analysis

Discover Chemistry
GOLPH3 is a PI(4)P-binding oncoprotein implicated in tumor progression, metastasis, and drug resistance, yet no direct small-molecule inhibitors of this target have been reported.
Zechariah Oluwapelumi Oresanya, Godswill Chimezirim Eleanya, Taiwo Abdulmaruf Akande, Titilayo Mary Jesugbemi, Rahmon Kanmodi   +4 more
doaj   +1 more source

underexpression is an independent prognostic marker in breast cancer [PDF]

core   +1 more source

Endometrium kanserlerinde golgi fosfoprotein 3 (GOLPH3) ekspresyonu ve prognozla ilişkisi

, 2020
Endometrium kanseri kadın genital sisteminin en sık görülen malign tümörüdür. Son yıllarda endometrium kanserinde mortaliteden ziyade ortaya çıkan yeni vaka sayısındaki artış durumu önem kazanmıştır. Bu nedenle prognozda etkili klinikopatolojik faktörler, mortalite riskinin ve hedefe yönelik gelişmiş tedavi stratejilerinin belirlenmesi amacıyla ...
openaire   +1 more source

The highly expressed <i>GOLPH3</i> in colorectal cancer cells activates smoothened to drive glycolysis and promote cancer cell growth and radiotherapy resistance. [PDF]

J Gastrointest Oncol
Zhu K, Fan J, Cai H, Zhou C, Gong Z, Li Z, Yu J.   +6 more
europepmc   +1 more source

rTMS ameliorates cerebral ischemia-reperfusion injury by inhibiting Golgi apparatus stress through epigenetic modulation of Gli2. [PDF]

Commun Biol
Zhu C, Fan Y, Peng W.
europepmc   +1 more source

Golgicide A induces pyroptosis of lung cancer stem cells by regulating dTGN formation via GOLPH3/MYO18A complex. [PDF]

Stem Cell Res Ther
Zhang F, Zhang SH, Liu T, Xie GS, Deng SH, Zhang T, Wang XB, Yang YY, Chen ZX, Wu DM, Xu Y.   +10 more
europepmc   +1 more source

GOLPH3 inhibition overcomes cisplatin resistance by restoring the glutathione/reactive oxygen species balance in the A549 non‑small cell lung cancer cell line. [PDF]

Oncol Rep
Wei Q, Lin J, Lin Z, Yu N, Wu Y, Tan X, Xue D.   +6 more
europepmc   +1 more source

New players and targets in mannose 6-phosphate-dependent lysosomal sorting. [PDF]

EMBO J
Zubkov N, Munro S.
europepmc   +1 more source

Trafficking and localization of Golgi-resident <i>N</i>-glycan processing enzymes in plants. [PDF]

Front Plant Sci
Dünser K, Schoberer J.
europepmc   +1 more source