Results 81 to 90 of about 2,164 (194)
The incidence and mortality of gastric cancer have been increasing in recent years. MiR-126 and target genes have been studied in gastric cancer, but their studies with Golgi phosphoprotein 3 (GOLPH3) and related pathways in gastric cancer are rarely ...
Jiancai Ouyang +4 more
doaj +1 more source
In eukaryotic cells, the trans-Golgi network (TGN) serves as a platform for secretory cargo sorting and trafficking. In recent years, it has become evident that a complex network of lipid-lipid and lipid-protein interactions contributes to these key ...
Hausser, A., von Blume, J.
core +1 more source
Mechanical Cues Regulate Cargo Sorting and Export at the Golgi
A pathway is identified linking extracellular matrix stiffness to secretion via Src–FAK–AMPK–GBF1 signaling. Golgi‐localized GBF1 acts as a mechanotransducer whose phosphorylation controls post‐Golgi cargo sorting toward secretion or lysosomal degradation.
Greta Serafino +21 more
wiley +1 more source
MiR-1/GOLPH3/Foxo1 Signaling Pathway Regulates Proliferation of Bladder Cancer [PDF]
Objective: To investigate role of microRNA-1/Golgi phosphoprotein 3/Foxo1 axis in bladder cancer. Methods: The expression of Golgi phosphoprotein 3 was determined in both bladder cancer tissues and cell lines using quantitative real ...
Ming-Kai Liu +6 more
openaire +2 more sources
Background To investigate the expression of Golgi phosphoprotein-3 (GOLPH3) in prostate cancer and determine its prognostic value. Methods Immunohistochemical staining for GOLPH3 was performed on tissue microarrays of 342 prostate patients.
Hua Xing +7 more
doaj +1 more source
Microvillar and ciliary defects in zebrafish lacking an actin-binding bioactive peptide amidating enzyme [PDF]
© The Author(s), 2018. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Scientific Reports 8 (2018): 4547, doi:10.1038/s41598-018-22732-9.The assembly of membranous ...
Eipper, Betty A. +6 more
core +2 more sources
Ythdc1‐p300‐Klf5 Complex‐Mediated Golgi Dysfunction Promotes Aortic Aneurysm
In their Research Article (DOI: https://doi.org/10.1002/advs.202512116* lF: 14.1 Q1), Wenli Wang and co‐workers identifies a novel lncRNA m6A modification‐dependent regulatory mechanism of vascular homeostasis, and constructs a predictive model for post‐operative short‐term death based on AD patient's features, providing a platform to be able to ...
Wen‐Li Wang +22 more
wiley +1 more source
Correlation of GOLPH3 Gene with Wnt Signaling Pathway in Human Colon Cancer Cells [PDF]
Overexpression of GOLPH3 in colorectal cancer tissue may promote cell proliferation and activate the Wnt signaling pathway. We investigated the correlation between GOLPH3 gene expression and the Wnt signaling pathway to explore the mechanism of the overexpression of GOLPH3 gene which promotes proliferation in human colon cancer cells.We measured ...
Qiu, Cheng-Zhi +5 more
openaire +2 more sources
Protosappanin B Exerts Anti-tumor Effects on Colon Cancer Cells via Inhibiting GOLPH3 Expression
Protosappanin B (PSB) is a key active component of Lignum Sappan extract. Although the antiproliferative effects of Lignum Sappan extract have been demonstrated in various cancer cells, relatively little is known about the effects of PSB on tumor ...
Xue-Cong Zheng +7 more
doaj +1 more source
Practical Outcomes From CASP16 for Users in Need of Biomolecular Structure Prediction
ABSTRACT The 16th Critical Assessment of Structure Prediction benchmarked advancements in biomolecular modeling, particularly in the context of AlphaFold 2 and 3 systems. Protein monomer and domain prediction is largely solved, with barely any space for further improvements at the backbone level except for very specific details, irregular secondary ...
Luciano A. Abriata, Matteo Dal Peraro
wiley +1 more source

