Results 61 to 70 of about 1,488 (184)

Increased expression of Golgi phosphoprotein-3 is associated with tumor aggressiveness and poor prognosis of prostate cancer

open access: yesDiagnostic Pathology, 2012
Background To investigate the expression of Golgi phosphoprotein-3 (GOLPH3) in prostate cancer and determine its prognostic value. Methods Immunohistochemical staining for GOLPH3 was performed on tissue microarrays of 342 prostate patients.
Hua Xing   +7 more
doaj   +1 more source

DNA Damage Triggers Golgi Dispersal via GOLPH3 and DNA-PK [PDF]

open access: yes, 2012
Golgi morphology and function has fascinated scientists for decades; however, it was unclear how the two were related. Our research delving into the function of GOLPH3 provides evidence for how Golgi morphology relates to Golgi trafficking. We identified
Farber-Katz, Suzette Elena
core  

PACS2 at Mitochondria‐Associated Membranes: A Central Regulator of Cardiovascular and Metabolic Diseases

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 16, August 2026.
ABSTRACT Cardiovascular and metabolic diseases (CVMDs), which are characterized by metabolic dysregulation and cardiovascular impairment, constitute a major global cause of mortality, thus highlighting the urgent need for novel therapeutic strategies. Phosphofurin acidic cluster sorting protein 2 (PACS2), a multifunctional adapter protein localized to ...
Baiyi Tang, Hui Wang, Jie Ouyang
wiley   +1 more source

Golgi Apparatus Target Proteins in Gastroenterological Cancers: A Comprehensive Review of GOLPH3 and GOLGA Proteins

open access: yesCells, 2023
The Golgi apparatus plays a central role in protein sorting, modification and trafficking within cells; its dysregulation has been implicated in various cancers including those affecting the GI tract.
Sandica Bucurica   +4 more
doaj   +1 more source

Epigenetic‐Based Evidence for Distinct Effects of Age, Sex, and Experience in Developmental Critical Period Learning

open access: yesDevelopmental Neurobiology, Volume 86, Issue 3, July 2026.
ABSTRACT Although much is known about the encoding of experience, how the brain organizes neural circuits capable of learning and memory formation is largely unstudied. Canonical critical periods emerge from a convergence of maturation‐ and experience‐dependent processes.
Grant W. Kunzelman   +2 more
wiley   +1 more source

GOLPH3: a novel biomarker that correlates with poor survival and resistance to chemotherapy in breast cancer [PDF]

open access: yesOncotarget, 2017
The association between Golgi phosphoprotein 3 (GOLPH3) and clinical pathological characteristics, as well as the clinical outcomes of both neoadjuvant and adjuvant chemotherapies in breast cancer, remain largely unknown. In this study, we investigated the biological role and clinical significance of GOLPH3 in breast cancer.
Tang, Shicong   +5 more
openaire   +2 more sources

The Flavonoids Daidzein and Genistein Induce Wall‐Deficient Cell Formation in Streptomyces coelicolor Under Hyperosmotic Stress

open access: yesMicrobial Biotechnology, Volume 19, Issue 6, June 2026.
Plant‐derived isoflavones (daidzein and genistein) function as chemical signals that induce stress‐dependent formation of wall‐deficient cells (S‐cells) in Streptomyces coelicolor. ABSTRACT Streptomycetes exhibit a complex multicellular life cycle, including programmed cell death and hyphal differentiation, and can generate extracellular vesicles and ...
Paula Valdés‐Chiara   +3 more
wiley   +1 more source

GOLPH3 overexpression correlates with tumor progression and poor prognosis in patients with clinically N0 oral tongue cancer

open access: yesJournal of Translational Medicine, 2012
Background Overexpression of GOLPH3 (Golgi phosphoprotein 3, 34 kDa) is associated with the progression of many solid tumor types leading to an unfavorable clinical outcome.
Li Huan   +7 more
doaj   +1 more source

Ligand‐specific tuning of CLEC10A signalling strength and dendritic cell responses through engagement of different GalNAc‐containing glycan structures

open access: yesThe FEBS Journal, Volume 293, Issue 11, Page 3187-3210, June 2026.
The authors investigated the effects of various glycan ligands for CLEC10A, a lectin receptor expressed on dendritic cells (DCs). Monocyte‐derived DCs were stimulated with glycan‐conjugated dendrimers in combination with the TLR1/2 ligand Pam3CysK4, and responses were investigated at the mRNA and protein level.
Nadia L. van der Meijs   +7 more
wiley   +1 more source

miR-126 targeting GOLPH3 inhibits the epithelial-mesenchymal transition of gastric cancer BGC-823 cells and reduces cell invasion

open access: yesEuropean Journal of Histochemistry, 2020
The incidence and mortality of gastric cancer have been increasing in recent years. MiR-126 and target genes have been studied in gastric cancer, but their studies with Golgi phosphoprotein 3 (GOLPH3) and related pathways in gastric cancer are rarely ...
Jiancai Ouyang   +4 more
doaj   +1 more source

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