Results 61 to 70 of about 1,488 (184)
Background To investigate the expression of Golgi phosphoprotein-3 (GOLPH3) in prostate cancer and determine its prognostic value. Methods Immunohistochemical staining for GOLPH3 was performed on tissue microarrays of 342 prostate patients.
Hua Xing +7 more
doaj +1 more source
DNA Damage Triggers Golgi Dispersal via GOLPH3 and DNA-PK [PDF]
Golgi morphology and function has fascinated scientists for decades; however, it was unclear how the two were related. Our research delving into the function of GOLPH3 provides evidence for how Golgi morphology relates to Golgi trafficking. We identified
Farber-Katz, Suzette Elena
core
ABSTRACT Cardiovascular and metabolic diseases (CVMDs), which are characterized by metabolic dysregulation and cardiovascular impairment, constitute a major global cause of mortality, thus highlighting the urgent need for novel therapeutic strategies. Phosphofurin acidic cluster sorting protein 2 (PACS2), a multifunctional adapter protein localized to ...
Baiyi Tang, Hui Wang, Jie Ouyang
wiley +1 more source
The Golgi apparatus plays a central role in protein sorting, modification and trafficking within cells; its dysregulation has been implicated in various cancers including those affecting the GI tract.
Sandica Bucurica +4 more
doaj +1 more source
ABSTRACT Although much is known about the encoding of experience, how the brain organizes neural circuits capable of learning and memory formation is largely unstudied. Canonical critical periods emerge from a convergence of maturation‐ and experience‐dependent processes.
Grant W. Kunzelman +2 more
wiley +1 more source
GOLPH3: a novel biomarker that correlates with poor survival and resistance to chemotherapy in breast cancer [PDF]
The association between Golgi phosphoprotein 3 (GOLPH3) and clinical pathological characteristics, as well as the clinical outcomes of both neoadjuvant and adjuvant chemotherapies in breast cancer, remain largely unknown. In this study, we investigated the biological role and clinical significance of GOLPH3 in breast cancer.
Tang, Shicong +5 more
openaire +2 more sources
Plant‐derived isoflavones (daidzein and genistein) function as chemical signals that induce stress‐dependent formation of wall‐deficient cells (S‐cells) in Streptomyces coelicolor. ABSTRACT Streptomycetes exhibit a complex multicellular life cycle, including programmed cell death and hyphal differentiation, and can generate extracellular vesicles and ...
Paula Valdés‐Chiara +3 more
wiley +1 more source
Background Overexpression of GOLPH3 (Golgi phosphoprotein 3, 34 kDa) is associated with the progression of many solid tumor types leading to an unfavorable clinical outcome.
Li Huan +7 more
doaj +1 more source
The authors investigated the effects of various glycan ligands for CLEC10A, a lectin receptor expressed on dendritic cells (DCs). Monocyte‐derived DCs were stimulated with glycan‐conjugated dendrimers in combination with the TLR1/2 ligand Pam3CysK4, and responses were investigated at the mRNA and protein level.
Nadia L. van der Meijs +7 more
wiley +1 more source
The incidence and mortality of gastric cancer have been increasing in recent years. MiR-126 and target genes have been studied in gastric cancer, but their studies with Golgi phosphoprotein 3 (GOLPH3) and related pathways in gastric cancer are rarely ...
Jiancai Ouyang +4 more
doaj +1 more source

