Results 71 to 80 of about 2,164 (194)
Cancer Cell International, 2022 Background Golgi phosphoprotein 3 (GOLPH3) has been frequently reported as an oncoprotein in a variety of tumors. However, its role in the cancer-associated intercellular signaling communication has not yet been explored.
Ying Gao +6 more
doaj +1 more source
Cells, 2023 The Golgi apparatus plays a central role in protein sorting, modification and trafficking within cells; its dysregulation has been implicated in various cancers including those affecting the GI tract.
Sandica Bucurica +4 more
doaj +1 more source
Granulosa cell apoptosis in the ovarian follicle - a changing view [PDF]
, 2018 Recent studies challenge the previous view that apoptosis within the granulosa cells of the maturing ovarian follicle is a reflection of aging and consequently a marker for poor quality of the contained oocyte.
Arun Dharmarajan +6 more
core +3 more sources
Developmental Neurobiology, Volume 86, Issue 3, July 2026.ABSTRACT Although much is known about the encoding of experience, how the brain organizes neural circuits capable of learning and memory formation is largely unstudied. Canonical critical periods emerge from a convergence of maturation‐ and experience‐dependent processes.
Grant W. Kunzelman +2 more
wiley +1 more source
Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration [PDF]
, 2014 Mutations in the vacuolar protein sorting 35 homolog (VPS35) gene at the PARK17 locus, encoding a key component of the retromer complex, were recently identified as a new cause of late-onset, autosomal dominant Parkinson's disease (PD).
A. Fiser +38 more
core +5 more sources
Rab1 interacts with GOLPH3 and controls Golgi structure and contractile ring constriction during cytokinesis in Drosophila melanogaster [PDF]
, 2017 Cytokinesis requires a tight coordination between actomyosin ring constriction and new membrane addition along the ingressing cleavage furrow. However, the molecular mechanisms underlying vesicle trafficking to the equatorial site and how this process is
Belloni, Giorgio +8 more
core +4 more sources
Microbial Biotechnology, Volume 19, Issue 6, June 2026.Plant‐derived isoflavones (daidzein and genistein) function as chemical signals that induce stress‐dependent formation of wall‐deficient cells (S‐cells) in Streptomyces coelicolor. ABSTRACT Streptomycetes exhibit a complex multicellular life cycle, including programmed cell death and hyphal differentiation, and can generate extracellular vesicles and ...
Paula Valdés‐Chiara +3 more
wiley +1 more source
Functional Characterization of Human Myosin-18A and Its Interaction with F-actin and GOLPH3 [PDF]
Journal of Biological Chemistry, 2013 Molecular motors of the myosin superfamily share a generic motor domain region. They commonly bind actin in an ATP-sensitive manner, exhibit actin-activated ATPase activity, and generate force and movement in this interaction. Class-18 myosins form heavy chain dimers and contain protein interaction domains located at their unique N-terminal extension ...
Taft, M. +5 more
openaire +4 more sources
Human Rhinovirus 16 Causes Golgi Apparatus Fragmentation without Blocking Protein Secretion [PDF]
, 2014 The replication of picornaviruses has been described to cause fragmentation of the Golgi apparatus that blocks the secretory pathway. The inhibition of major histocompatibility complex class I upregulation and cytokine, chemokine and interferon secretion
Guedan, A +7 more
core +2 more sources
Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.• STK25 deficiency enhanced CAF‐mediated CRC growth via the NF‐κB/AREG/EGFR axis. • STK25 overexpression or AREG antibody overcame CAF‐mediated cetuximab resistance. • CRC patients with high STK25 and low CAFs marker levels might benefit from cetuximab treatment.
Yifan Hou +17 more
wiley +1 more source