Cellular Physiology and Biochemistry, 2015 Background/Aims: Golgi phosphoprotein 3 (GOLPH3) is a newly reported oncogene that plays a significant role in regulating cell growth. Recent research has shown that overexpression of GOLPH3 is correlated with patient survival and M classification in ...
Ran Wang +6 more
doaj +1 more source
PLoS ONE, 2019 Golgi phosphoprotein 3 (GOLPH3) is a conserved protein of the Golgi apparatus that in humans has been implicated in tumorigenesis. However, the precise function of GOLPH3 in malignant transformation is still unknown.
Cecilia Arriagada +8 more
doaj +1 more source
Human Golgi phosphoprotein 3 is an effector of RAB1A and RAB1B.
PLoS ONE, 2020 Golgi phosphoprotein 3 (GOLPH3) is a peripheral membrane protein localized at the trans-Golgi network that is also distributed in a large cytosolic pool.
Viviana A Cavieres +7 more
doaj +1 more source
Golgi Phosphoprotein 3 Promotes Wls Recycling and Wnt Secretion in Glioma Progression
Cellular Physiology and Biochemistry, 2018 Background/Aims: Golgi phosphoprotein 3 (GOLPH3) plays pro-malignancy roles in several types of cancer. However, the molecular mechanism underlying GOLPH3 promoting tumor progression remains poorly understood.
Dong Lu +7 more
doaj +1 more source
Golgi Phosphoprotein 3 Mediates Radiation-Induced Bystander Effect via ERK/EGR1/TNF-α Signal Axis
Antioxidants, 2022 The radiation-induced bystander effect (RIBE), an important non-targeted effect of radiation, has been proposed to be associated with irradiation-caused secondary cancers and reproductive damage beyond the irradiation-treated area after radiotherapy ...
Feng Qin +9 more
doaj +1 more source
Mechanistic basis of an epistatic interaction reducing age at onset in hereditary spastic paraplegia [PDF]
, 2018 Many genetic neurological disorders exhibit variable expression within affected families, often exemplified by variations in disease age at onset. Epistatic effects (i.e. effects of modifier genes on the disease gene) may underlie this variation, but the
Allison, R +19 more
core +1 more source
Bridging the Gap between Glycosylation and Vesicle Traffic [PDF]
, 2016 Glycosylation is recognized as a vitally important posttranslational modification. The structure of glycans that decorate proteins and lipids is largely dictated by biosynthetic reactions occurring in the Golgi apparatus.
Abdul Rahman +105 more
core +2 more sources
Potential impact of primate‐specific SVA retrotransposons during the evolution of human cognitive function. [PDF]
, 2017 The SVA family of hominid-specific non-LTR retrotransposon comprises the youngest group of transposable elements in the human genome. The propagation of the most ancient SVA subfamily took place about 13.5 million years ago, and the youngest SVA ...
Bubb, VJ +5 more
core +1 more source
Combining Genome Wide Association Studies and Differential Gene Expression Data Analyses Identifies Candidate Genes Affecting Mastitis Caused by Two Different Pathogens in the Dairy Cow [PDF]
, 2015 Mastitis is a costly disease which hampers the dairy industry. Inflammation of the mammary gland is commonly caused by bacterial infection, mainly Escherichia coli, Streptococcus uberis and Staphylococcus aureus.
Chen, X +4 more
core +3 more sources
High relative density of lymphatic vessels predicts poor survival in tongue squamous cell carcinoma [PDF]
, 2016 Tongue cancer has a poor prognosis due to its early metastasis via lymphatic vessels. The present study aimed at evaluating lymphatic vessel density, relative density of lymphatic vessel, and diameter of lymphatic vessels and its predictive role in ...
Huhtala, Heini +8 more
core +1 more source