Results 111 to 120 of about 115,721 (241)

The hypothalamic-pituitary-adrenal axis in critical illness [PDF]

open access: yes, 1993
Plasma ACTH and cortisol concentrations are frequently elevated in patients in intensive care units (ICU). To examine the functional integrity of the hypothalamic-pituitary-adrenal axis during critical illness, we evaluated prospectively 53 ICU patients ...
Winkelmann, W.   +3 more
core   +1 more source

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

open access: yesBritish Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral   +3 more
wiley   +1 more source

Pubertal Dynamics of Sertoli and Leydig Cell Dysfunction in Klinefelter Syndrome

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Context Klinefelter syndrome (KS), defined by a 47, XXY karyotype, is commonly associated with progressive testicular failure. The precise timing of Sertoli and Leydig cell dysfunction during puberty remains unclear. Objective To determine the onset and progression of testicular insufficiency during puberty in KS, and to assess whether ...
Tredez Axelle   +9 more
wiley   +1 more source

Molecular network study of pituitary adenomas

open access: yes, 2020
Pituitary adenomas are a category of neoplasms with a high degree of heterogeneity that occur in the central regulatory organ pituitary, which plays important roles in the hypothalamus–pituitary-targeted organ axis systems that impact on important ...

core   +1 more source

Current Approaches to Support Patients to Withdraw From Image and Performance Enhancing Drugs

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Image and performance‐enhancing drugs (IPEDs) include agents such as androgens, growth hormone, and erythropoietin, which are used to enhance appearance and physical performance. Androgens, also known as anabolic‐androgenic steroids (AAS), are the most used IPEDs worldwide.
Elizabeth Hyams   +3 more
wiley   +1 more source

New insights into spexin and pituitary adenylate cyclase-activating polypeptide (PACAP) in regulating fish reproduction

open access: yesAquaculture and Fisheries
Reproduction is one of the most crucial physiological processes for the continuation of the generation of any species. Teleost are one of the most divergent aquatic species.
Ashis Saha   +3 more
doaj   +1 more source

Biochemical profiling and symptomatology of androgen deficiency in males with cluster headache: A prospective case–control study

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background Cluster headache (CH) has historically been considered a male‐dominated disorder, suggesting a role for androgens in its pathophysiology. We aimed to evaluate hormone profiles and symptoms of androgen deficiency in CH.
Willemijn C. Naber   +7 more
wiley   +1 more source

Continuous darkness is associated with improved growth performance during a high‐temperature period and sex‐specific modulation of early gonadal development in juvenile yellowtail (Seriola quinqueradiata)

open access: yesJournal of Fish Biology, EarlyView.
Abstract Selective breeding of yellowtail (Seriola quinqueradiata) is expanding in Japan, increasing the demand for practical reproductive control tools in commercial aquaculture to reduce genetic risks from escapees. Slowing early gonadal development through environmental manipulation may support future sterilization strategies, particularly when ...
Yuya Hasegawa   +3 more
wiley   +1 more source

Pituitary headache

open access: yes, 2015
The ready access to brain imaging has resulted in an increased detection of incidentally discovered pituitary lesions. Radiological and post mortem studies report the prevalence of pituitary incidentalomas to be as high as 10%.1 Exclusion of secondary ...
Miles J Levy
core   +1 more source

Black Carp Mylopharyngodon piceus reproductive development and maturation in the Mississippi River basin

open access: yesJournal of Fish Biology, EarlyView.
Abstract Black Carp Mylopharyngodon piceus are native to most major east Asian drainages and are internationally cultured for use as a food‐fish or a biological control for molluscs. We describe the reproductive biology of Black Carp from the growing invasive population in the Mississippi River basin through examination of incidental commercial ...
Patrick T. Kroboth   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy