Results 151 to 160 of about 2,350,416 (333)

Comparison of Good Clinical Practice Inspection Process for Marketing Applications Between the United States Food and Drug Administration and the European Medicines Agency

, 2022
Kassa Ayalew, Yang‐Min Ning, Michelle Foringer, Susan Leibenhaut, Jenn W. Sellers, Bei Yu, Phillip D. Kronstein, Agata Higgerson, Camelia Mihaescu, Miguel Rodriguez, LaKisha Williams, Ni Khin   +11 more
openalex   +1 more source

"Good enough" training in clinical practice for BPD? [PDF]

, 2017
Charbon, P., Despland, J.-N., Kolly, S., Kramer, U.   +3 more
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Management goals of type 1 Gaucher disease in South Africa: An expert Delphi consensus document on good clinical practice. [PDF]

PLoS One, 2023
Louw VJ, Fraser I, Giraldo P.
europepmc   +1 more source

Accreditation of training courses in good clinical practice

, 2010
Raymond P. Abratt, Alistair Hunter
openalex   +2 more sources

HOW GOOD ARE LOW BACK PAIN GUIDELINES? A CRITICAL APPRAISAL OF THE QUALITY OF CLINICAL PRACTICE GUIDELINES USING THE AGREE II TOOL [PDF]

, 2020
Valerio Iannicelli, Greta Castellini, Matteo Briguglio, Davide Corbetta, Luca Maria Sconfienza, Giuseppe Banfi, Silvia Gianola   +6 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Ex vivo-expanded highly pure ABCB5+ mesenchymal stromal cells as Good Manufacturing Practice-compliant autologous advanced therapy medicinal product for clinical use: process validation and first in-human data [PDF]

, 2020
Andreas Kerstan, Elke Niebergall‐Roth, Jasmina Esterlechner, Hannes M. Schröder, Martin Gasser, Ana Maria Waaga-Gasser, Matthias Goebeler, Katrin Rak, Philipp Schrüfer, Sabrina Endres, Petra Hagenbusch, Korinna Kraft, Kathrin Dieter, Seda Ballikaya, Nicole Stemler, Samar Sadeghi, Nils Tappenbeck, Gëorge F. Murphy, Dennis P. Orgill, Natasha Y. Frank, Christoph Ganss, Karin Scharffetter‐­Kochanek, Markus H. Frank, Mark A. Kluth   +23 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source