PLoS ONE, 2020 The tolerance of ruminants to gossypol, a natural phenolic compound derived from the cotton plant, is greater than that of monogastric animals, partially because of the gossypol-degrading bacteria in the rumen of the ruminants. In this study, we aimed to
CaiDie Wang +4 more
doaj +3 more sources
Screening of a Gossypol-Removing Yeast Strain and Characterization of Its Removal Mechanism [PDF]
MicroorganismsGossypol, a polyphenolic naphthalene derivative and yellow polyphenolic pigment found in cotton seed glands, presents notable environmental, animal, and human health hazards.
Yushuo Zhang +5 more
doaj +2 more sources
Gossypol detoxification in the rumen and Helicoverpa armigera larvae: A review
Animal Nutrition, 2021 Gossypol, a phenolic compound found in the cotton plant, is widely distributed in cottonseed by-products. Although ruminant animals are believed to be more tolerant of gossypol toxicity than monogastric animals due to rumen microbial fermentation, the ...
Wei-Kang Wang, Hong-Jian Yang
exaly +3 more sources
CRISPR/Cas9-mediated mutation of GhCAD decreases the gossypol content of cottonseed [PDF]
Journal of Biological EngineeringCottonseed is the most important byproduct of cotton production. However, high free gossypol contents limit the application of cottonseed in the food or feed industry.
Lili Zhou +8 more
doaj +2 more sources
Transcriptional responses underlying the hormetic and detrimental effects of the plant secondary metabolite gossypol on the generalist herbivore
BMC Genomics, 2011 Background Hormesis is a biphasic biological response characterized by the stimulatory effect at relatively low amounts of chemical compounds which are otherwise detrimental at higher concentrations.
de la Paz Celorio-Mancera Maria +3 more
doaj +2 more sources
Presence of free gossypol in whole cottonseed [PDF]
EFSA Journal, 2017 The European Commission asked EFSA to assess information provided by the Spanish Ministry of Agriculture, Food and Environment, on the toxicity of free gossypol in relation to the use of whole cotton seed in feed for ruminants, in particular dairy cows ...
EFSA Panel on Contaminants in the Food Chain (CONTAM) +22 more
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Molecular Target Identification of Gossypol Against Cervical Cancer Based on Target Fishing Technology [PDF]
PharmaceuticsObjectives: This study aims to investigate the impact of Gossypol on human cervical cancer cells and elucidate its mechanism of action to establish a foundation for further clinical investigations.
Jinyan Li +6 more
doaj +2 more sources
Heterologous Overexpression of Cytochrome P450BM3 from <i>Bacillus megaterium</i> and Its Role in Gossypol Reduction. [PDF]
Toxins (Basel)Fan W +6 more
europepmc +3 more sources
The reversible effects of gossypol toxicity on male pigeons' reproductive performance [PDF]
Veterinary World, 2022 Background and Aim: Gossypol, a cotton seed derivative, is well known for its reversible antifertility in male reproduction across species. Its antifertility and reversibility effects on male reproductive function vary among species in dose-and time ...
Suwarak Wannaratana +3 more
doaj +1 more source