CRISPR/Cas9-mediated mutation of GhCAD decreases the gossypol content of cottonseed [PDF]
Journal of Biological EngineeringCottonseed is the most important byproduct of cotton production. However, high free gossypol contents limit the application of cottonseed in the food or feed industry.
Lili Zhou +8 more
doaj +4 more sources
Effect of dietary cotton stalk on nitrogen and free gossypol metabolism in sheep [PDF]
Asian-Australasian Journal of Animal Sciences, 2019 Objective This study was to investigate the effects of dietary cotton stalk on nitrogen and free gossypol in sheep. Methods Treatments included 25% cotton stalk (Treat 1), 50% cotton stalk (Treat 2), and a control (no cotton stalk).
Halidai Rehemujiang +2 more
doaj +3 more sources
Screening of a Gossypol-Removing Yeast Strain and Characterization of Its Removal Mechanism [PDF]
MicroorganismsGossypol, a polyphenolic naphthalene derivative and yellow polyphenolic pigment found in cotton seed glands, presents notable environmental, animal, and human health hazards.
Yushuo Zhang +5 more
doaj +2 more sources
Biomolecules, 2023 Gossypol is a complex plant polyphenol reported to be cytotoxic and anti-inflammatory, but little is known about its effect on gene expression in macrophages.
Heping Cao, Kandan Sethumadhavan
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Molecular Target Identification of Gossypol Against Cervical Cancer Based on Target Fishing Technology [PDF]
PharmaceuticsObjectives: This study aims to investigate the impact of Gossypol on human cervical cancer cells and elucidate its mechanism of action to establish a foundation for further clinical investigations.
Jinyan Li +6 more
doaj +2 more sources
Isolation and Identification of a Rumen Lactobacillus Bacteria and Its Degradation Potential of Gossypol in Cottonseed Meal during Solid-State Fermentation [PDF]
Microorganisms, 2021 Cottonseed meal (CSM) is an important protein feed source for dairy cows. Its inclusion in ruminant diets is limited due to the presence of the highly toxic gossypol though rumen microorganisms are believed to be capable of gossypol degrading and ...
Wei-Kang Wang +5 more
doaj +2 more sources
Metabolomic Profiling and Network Toxicology: Mechanistic Insights into Effect of Gossypol Acetate Isomers in Uterine Fibroids and Liver Injury [PDF]
PharmaceuticalsObjective: Gossypol is a natural polyphenolic dialdehyde product that is primarily isolated from cottonseed. It is a racemized mixture of (−)-gossypol and (+)-gossypol that has anti-infection, antimalarial, antiviral, antifertility, antitumor and ...
Zishuo Liu, Hui Zhang, Jun Yao
doaj +2 more sources
Gossypol Toxicity from Cottonseed Products
Scientific World Journal, The, 2014 Gossypol is a phenolic compound produced by pigment glands in cotton stems, leaves, seeds, and flower buds (Gossypium spp.). Cottonseed meal is a by-product of cotton that is used for animal feeding because it is rich in oil and proteins.
Benito Soto-Blanco
exaly +2 more sources
Methods of obtaining activated adsorbents based on gossypol tar and local bentonites and analysis of their physical parameters [PDF]
E3S Web of ConferencesThis article provides information on the methods of obtaining activated adsorbents based on oil-oil waste gossypol tar and local benonites and their various physical properties.
Ochilov Golibjon +2 more
doaj +2 more sources
A Spin-Labeled Derivative of Gossypol [PDF]
MoleculesGossypol and its derivatives arouse interest due to their broad spectrum of biological activities. Despite its wide potential application, there is no reported example of gossypol derivatives bearing stable radical functional groups.
Andrey V. Stepanov +8 more
doaj +2 more sources