Results 21 to 30 of about 14,284 (259)
Cotton roots are the major source of gossypol biosynthesis and accumulation
BMC Plant Biology, 2020 Background Gossypol is a specific secondary metabolite in Gossypium species. It not only plays a critical role in development and self-protection of cotton plants, but also can be used as important anti-cancer and male contraceptive compound.
Tianlun Zhao +7 more
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Gossypol improves myocardial dysfunction caused by sepsis by regulating histone acetylation
Clinical and Translational Science, 2023 Gossypol is a polyphenol from the cotton plant with anti‐inflammatory and anti‐oxidation activities and can also function as a histone deacetylase (HDAC) inhibitor. Sepsis is an inflammatory disease with high mortality.
Xiaohui Shi, Xinwei Lv, Dong Xiao
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Gossypol detoxification in the rumen and Helicoverpa armigera larvae: A review
Animal Nutrition, 2021 Gossypol, a phenolic compound found in the cotton plant, is widely distributed in cottonseed by-products. Although ruminant animals are believed to be more tolerant of gossypol toxicity than monogastric animals due to rumen microbial fermentation, the ...
Wei-Kang Wang +5 more
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Prenatal Exposure to Gossypol Impairs Corticogenesis of Mouse
Frontiers in Neuroscience, 2020 Gossypol is a yellow polyphenolic compounds extracted from roots, stems and seeds of cotton plants. Excessive intake of gossypol induces severe pathological signs of toxicity in livestock and wildlife.
Xiaoyan Zhu +6 more
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Seasonal Dietary Patterns of Tarim Red Deer (<i>Cervus hanglu yarkandensis</i>) Revealed by the <i>trnL</i> Sequencing Approach in the Tarim River Basin (Xinjiang, China). [PDF]
Ecol EvolThis study employed DNA metabarcoding technology to analyze the seasonal dietary habits of Tarim red deer in Xinjiang within a mixed habitat of Populus euphratica and cotton. Results indicate a primary reliance on cotton (38.75%) and European poplar (36.87%). Summer dietary diversity and ecological niche breadth were significantly higher than in winter
Qi C +5 more
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Asian Pacific Journal of Tropical Biomedicine, 2021 Objective: To isolate, purify, and characterize gossypol from the fruits of Thespesia populnea (L) Sol. ex Correa, test its anti- dermatophytic activity, identify its targets on the dermatophyte, and confirm the binding of gossypol with the fungal target
R Anuthara +2 more
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(±)-Gossypol induces apoptosis and autophagy in head and neck carcinoma cell lines and inhibits the growth of transplanted salivary gland cancer cells in BALB/c mice [PDF]
, 2016 Racemic Gossypol [(±)-GOS], composed of both (-)-GOS and (+)-GOS, is a small BH3-mimetic polyphenol derived from cotton seeds. (±)-GOS has been employed and well tolerated by cancer patients. Head and neck carcinoma (HNC) represents one of the most fatal
Andracchio, Orlando +10 more
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BMC Plant Biology, 2023 Background Gossypol is a unique secondary metabolite and sesquiterpene in cotton, which is mainly synthesized in the root system of cotton and exhibits many biological activities.
Kun Ye +4 more
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Gossypol Suppresses Growth of Temozolomide-Resistant Glioblastoma Tumor Spheres
Biomolecules, 2019 Temozolomide is the current first-line treatment for glioblastoma patients but, because many patients are resistant to it, there is an urgent need to develop antitumor agents to treat temozolomide-resistant glioblastoma.
Hee Yeon Kim +8 more
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