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Nature Reviews Disease Primers, 2019 Gout is a chronic disease caused by monosodium urate (MSU) crystal deposition. Gout typically presents as an acute, self-limiting inflammatory monoarthritis that affects the joints of the lower limb. Elevated serum urate level (hyperuricaemia) is the major risk factor for MSU crystal deposition and development of gout. Although traditionally considered
Dalbeth, N. +6 more
semanticscholar +8 more sources
The Lancet, 2021 Gout is a common and treatable disease caused by the deposition of monosodium urate crystals in articular and non-articular structures. Increased concentration of serum urate (hyperuricaemia) is the most important risk factor for the development of gout.
Nicola, Dalbeth +3 more
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Frontiers in Microbiology, 2022 A high-purine diet can cause hyperuricemia and destroy the microbial composition of the gut microbiota. Both folic acid and zinc significantly reduce uric acid levels and alleviate hyperuricemia.
Xuewei Sun +15 more
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Systematic Reviews, 2021 Background The Reporting Items for Practice Guidelines in Healthcare (RIGHT) checklist was used to assess the reporting quality of 2009–2019 clinical practice guidelines (CPGs) regarding gout and hyperuricemia, aimed to improve the reporting quality of ...
Can Wang +12 more
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Arthritis Research & Therapy, 2023 Background Low urine pH, which may be mediated by metabolic syndrome (MetS), is common in gout. Tart cherries are shown to improve MetS symptoms and possess anti-inflammatory properties.
Can Wang +14 more
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Impact of Oral Microbiota on Flavor Perception: From Food Processing to In-Mouth Metabolization
Foods, 2021 Flavor perception during food intake is one of the main drivers of food acceptability and consumption. Recent studies have pointed to the oral microbiota as an important factor modulating flavor perception.
Mathieu Schwartz +4 more
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Advances in Rheumatology, 2023 Objectives The deposition of monosodium urate (MSU) crystals within synovial joints and tissues is the initiating factor for gout arthritis. Thus, MSU crystals are a vital tool for studying gout’s molecular mechanism in animal and cellular models.
Fei Yan +9 more
doaj +1 more source
Gut Microbiota in Systemic Lupus Erythematosus and Correlation With Diet and Clinical Manifestations
Frontiers in Medicine, 2022 Despite the existing studies relating systemic lupus erythematosus (SLE) to changes in gut microbiota, the latter is affected by external factors such as diet and living environment.
Xiao Wang +10 more
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Gout. Epidemiology of gout [PDF]
Arthritis Research & Therapy, 2010 Gout is the most prevalent form of inflammatory arthropathy. Several studies suggest that its prevalence and incidence have risen in recent decades. Numerous risk factors for the development of gout have been established, including hyperuricaemia, genetic factors, dietary factors, alcohol consumption, metabolic syndrome, hypertension, obesity, diuretic
Edward Roddy, Michael C Doherty
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