Results 1 to 10 of about 70 (62)
Rheumatic Disease Clinics of North America, 2019 The treat to target strategy looks attractive for management of gout because it removes the causal mechanism inducing formation, growth, and aggregation of urate crystals. Further reduction of serum urate (sUA) levels below the threshold may dissolve crystals more rapidly. It is generally agreed that sUA less than 6 mg/dL is acceptable as a therapeutic
Fernando, Perez-Ruiz, Nicola, Dalbeth
exaly +11 more sources
The Lancet, 2021 Gout is a common and treatable disease caused by the deposition of monosodium urate crystals in articular and non-articular structures. Increased concentration of serum urate (hyperuricaemia) is the most important risk factor for the development of gout.
Nicola, Dalbeth +3 more
openaire +4 more sources
New England Journal of Medicine, 2023 To the Editor: The Clinical Practice review on gout by Mikuls (Nov. 17 issue)1 underscores the importance of hyperuricemia as a necessary risk factor and mentions the high heritability of serum urate levels.2 Serum urate levels are mostly controlled by the kidney, as confirmed by genetic studies implicating both rare and common variants in transporters
Devuyst, Olivier +2 more
openaire +4 more sources
American Journal of Case Reports, 2021 BACKGROUND Gout is a chronic disease characterized by deposition of monosodium urate crystals, typically manifesting as arthritis. Clinical presentation of gout usually results from activation of local inflammatory response. Despite being one of the oldest diseases in the world, gout pathophysiology is incompletely understood and clinical features are ...
Martins, Danilo +13 more
openaire +4 more sources
Gout. Epidemiology of gout [PDF]
Arthritis Research & Therapy, 2010 Gout is the most prevalent form of inflammatory arthropathy. Several studies suggest that its prevalence and incidence have risen in recent decades. Numerous risk factors for the development of gout have been established, including hyperuricaemia, genetic factors, dietary factors, alcohol consumption, metabolic syndrome, hypertension, obesity, diuretic
Roddy, Edward, Doherty, Michael
openaire +1 more source
Medical Journal of Australia, 1972 We now have sufficient knowledge to be able to identify the factors contributing to hyperuricemia in most patients with gout. Some of these factors, such as obesity, a high-purine diet, regular alcohol consumption, and diuretic therapy, may be correctable.
openaire +7 more sources
ON IRREGULAR GOUT, WITH REMARKS ON THE PATHOLOGY OF GOUT. [PDF]
The Lancet, 1880 n ...
openaire +1 more source