Results 181 to 190 of about 78,942 (265)

Association between higher estimated glucose disposal rate and reduced prevalence of hyperuricemia and gout [PDF]

open access: gold
Pengfei Liu   +7 more
openalex   +1 more source

Metabolic dysfunction-associated fatty liver disease and the risk of gout: a UK Biobank prospective cohort study. [PDF]

open access: yesEur J Med Res
Liu X   +9 more
europepmc   +1 more source

Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives

open access: yesAdvanced Photonics Research, Volume 6, Issue 12, December 2025.
Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka   +5 more
wiley   +1 more source

Further Evidence That Chondrocalcinosis 1 (CCAL1) is a Confirmed Mendelian Phenotype With a Known Molecular Basis

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 12, December 2025.
ABSTRACT Chondrocalcinosis (CCAL), also known as calcium pyrophosphate dihydrate deposition disease (CPPDD), is a frequent multifactorial condition in the elderly, but there are two rare autosomal dominant Mendelian forms, CCAL1 (OMIM %600668) and CCAL2. Only three families with molecularly proven CCAL1 have been reported.
Anna‐Christina Pansa   +4 more
wiley   +1 more source

Genomic and clinical correlates of 5 deep learning‐based neuroimaging signatures of neurodegeneration, evaluated in ADSP

open access: yesAlzheimer's &Dementia, Volume 21, Issue S1, December 2025.
Abstract Background Deep learning methods help to disentangle heterogeneity of brain aging and find distinct neuroimaging patterns of neurodegeneration. However, the relationship between aging‐related brain atrophy patterns and genetics is complex and requires further exploration.
Yuhan Cui   +9 more
wiley   +1 more source

Peptide/Antibody–Drug Conjugates for Therapeutic Applications in Inflammatory Disease

open access: yesAdvanced NanoBiomed Research, Volume 5, Issue 12, December 2025.
Peptide/antibody–drug conjugates (PADCs) combine ligand specificity and cleavable linkers to deliver drugs precisely to disease sites with minimal toxicity. While current approvals focus on oncology, this review examines their untapped potential in inflammatory diseases, detailing mechanisms of targeted delivery and highlighting advances that position ...
Yeongji Jang   +5 more
wiley   +1 more source

Structural Studies of Sodium Counterion on Naproxen: From Solid State to Stability

open access: yesAdvanced Physics Research, Volume 4, Issue 12, December 2025.
Naproxen is a widely used nonsteroidal anti‐inflammatory drug with limited aqueous solubility. This study investigates how the sodium counterion influences naproxen's structural, supramolecular, and electronic properties. Hirshfeld surface analysis, QTAIM, and DFT calculations reveal that sodium enhances reactivity, polarity, and solubility ...
Antônio S. N. Aguiar   +6 more
wiley   +1 more source

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