Association between higher estimated glucose disposal rate and reduced prevalence of hyperuricemia and gout [PDF]
Pengfei Liu +7 more
openalex +1 more source
Metabolic dysfunction-associated fatty liver disease and the risk of gout: a UK Biobank prospective cohort study. [PDF]
Liu X +9 more
europepmc +1 more source
Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives
Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka +5 more
wiley +1 more source
ABSTRACT Chondrocalcinosis (CCAL), also known as calcium pyrophosphate dihydrate deposition disease (CPPDD), is a frequent multifactorial condition in the elderly, but there are two rare autosomal dominant Mendelian forms, CCAL1 (OMIM %600668) and CCAL2. Only three families with molecularly proven CCAL1 have been reported.
Anna‐Christina Pansa +4 more
wiley +1 more source
Association between frailty and gout in middle-aged and older adults: A nationwide cross-sectional and Mendelian randomization study. [PDF]
Sun Y +8 more
europepmc +1 more source
Abstract Background Deep learning methods help to disentangle heterogeneity of brain aging and find distinct neuroimaging patterns of neurodegeneration. However, the relationship between aging‐related brain atrophy patterns and genetics is complex and requires further exploration.
Yuhan Cui +9 more
wiley +1 more source
Peptide/Antibody–Drug Conjugates for Therapeutic Applications in Inflammatory Disease
Peptide/antibody–drug conjugates (PADCs) combine ligand specificity and cleavable linkers to deliver drugs precisely to disease sites with minimal toxicity. While current approvals focus on oncology, this review examines their untapped potential in inflammatory diseases, detailing mechanisms of targeted delivery and highlighting advances that position ...
Yeongji Jang +5 more
wiley +1 more source
Structural Studies of Sodium Counterion on Naproxen: From Solid State to Stability
Naproxen is a widely used nonsteroidal anti‐inflammatory drug with limited aqueous solubility. This study investigates how the sodium counterion influences naproxen's structural, supramolecular, and electronic properties. Hirshfeld surface analysis, QTAIM, and DFT calculations reveal that sodium enhances reactivity, polarity, and solubility ...
Antônio S. N. Aguiar +6 more
wiley +1 more source
Global burden of gout among young people from 1990 to 2021, with projections for 2050: A systematic analysis based on the Global Burden of Disease Study 2021. [PDF]
Tian P +6 more
europepmc +1 more source

