Results 151 to 160 of about 18,703 (209)

IL-6/IL-6R-Mediated Mechanisms in Lung Cancer: From Pathogenesis to Potential Therapeutic Targets. [PDF]

Immunology
Abuhassan Q, Al-Ameer HJ, Jyothi SR, Nayak PP, Prakash P, Mukherjee G, Sinha A, Hazratkulova O.   +7 more
europepmc   +1 more source

The role and mechanism of IL‑35 in myasthenia gravis (Review). [PDF]

Int J Mol Med
Mao J, Zhang LM, Zhu YL, Gao SJ, Liu MW.
europepmc   +1 more source

The role of IL-11 in chronic diseases. [PDF]

Front Immunol
Zhang J, Leng Y, Li W, Wang B, Yang B, Li W.   +5 more
europepmc   +1 more source

Interleukin-6 in complications of prematurity: from biomarker to targeted therapy. [PDF]

Front Pediatr
Xiao S, Zheng Q, Wang L, Wang Z, Bi G, Yang J.   +5 more
europepmc   +1 more source

iBody-mediated tuning of synthetic cytokine receptor activation via rational nanobody interface engineering. [PDF]

MAbs
Kunze R, Navratil F, Beichert J, Geyer F, Floss DM, Kolmar H, Scheller J, Pudewell S.   +7 more
europepmc   +1 more source

PD-L1 autoregulation promotes the proliferation, migration and invasion of glioblastoma cells via GP130/JAK2/STAT3/IRAK2/IL6 signaling pathway. [PDF]

Sci Rep
Xie X, Bai J, Peng Y, Chen P, Zhang Z, Fan D, Zhou F, Yuan Y, Liu J, Zhou Y, Hong Q, Hu J, Duan J, Fu W, Zhang T, Zeng H, Deng J, Dong Y, Liu Y, Qi X, Hong W, He Y, Zhang C, Yu W, Yang Q, Yi W, Bai H, Zhang Q.   +27 more
europepmc   +1 more source

Receptor recognition by gp130 cytokines [PDF]

EMBO Journal, 2000
Cytokines of the gp130 family exert their diverse biological effects by formation of stable high affinity transmembrane receptor complexes that are characterized by the presence of the shared transmembrane signalling receptor gp130. Different gp130 ligands form signalling complexes that vary in both composition and stoichiometry.
Jerónimo Bravo, John K Heath
exaly   +4 more sources

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Interleukin‐11: A gp130 Cytokine

Annals of the New York Academy of Sciences, 1998
ABSTRACT: Interleukin (IL)‐11 is a member of the gp130 family of cytokines. Comparison of IL‐11 with another gp130 family member, IL‐6, indicates that these two cytokines share many overlapping signal transduction mechanisms. However, unlike IL‐6, treatment of patients with a recombinant human form of IL‐11 (rhIL‐11) does not increase body temperature,
William L, Trepicchio, Andrew J, Dorner
openaire   +2 more sources

Activation of the gp130 signaling pathway by monoclonal antibodies directed against the gp130 molecule

European Journal of Immunology, 1997
AbstractSix cytokines of the interleukin (IL)‐6 family involved in various inflammatory or tumoral diseases share the same gp130 signal transducer chain. We made a panel of anti‐gp130 monoclonal antibodies (mAb) to study the structure and function of the gp130 molecule. These mAb recognized different epitopes of the gp130 that we called A to J. Most of
P, Autissier, J, Liautard, J, Brochier, J P, Gaillard   +3 more
openaire   +2 more sources