Results 101 to 110 of about 24,285 (259)

Engineering Pseudomonas protegens as a Targeted Antifungal‐Effector Delivery Chassis via Heterologous Type III Secretion System Reconstitution

Microbial Biotechnology, Volume 19, Issue 6, June 2026.
A heterologous T3SS turns Pseudomonas protegens Pf‐5 into a programmable molecular syringe that delivers Bg9562 into Fusarium hyphae, suppresses fungal pathogens, enhances rhizosphere colonization and protects tomato plants from wilt. This modular platform offers a transferable strategy for next‐generation fungal biocontrol.
Yuyuan Peng, Simei He, Guofan Zhang, Jiatao Yang, Rong Fan, Chen Li, Jiajie Xie, Xinran Long, Linger Qian, Jiayi Wang, Yanmin He, Hui Cai, Yushan Zhang, Qiuqian Zhang, Shaopeng Pan, Shengbiao Hu   +15 more
wiley   +1 more source

Combination of anti-retroviral drugs and radioimmunotherapy specifically kills infected cells from HIV infected individuals

Frontiers in Medicine, 2016
Eliminating virally infected cells is an essential component of any HIV eradication strategy. Radioimmunotherapy (RIT), a clinically established method for killing cells using radiolabeled antibodies, was recently applied to target HIV-1 gp41 antigen ...
Dina Tsukrov, Alicia McFarren, Alfred Morgenstern, Frank Bruchertseifer, Eugene Dolce, Miroslaw K Gorny, Susan Zolla-Pazner, Joan W Berman, Ellie Schoenbaum, Barry S Zingman, Arturo Casadevall, Ekaterina Dadachova   +11 more
doaj   +1 more source

Gp41-targeted antibodies restore infectivity of a fusion-deficient HIV-1 envelope glycoprotein.

PLoS Pathogens, 2020
The HIV-1 envelope glycoprotein (Env) mediates viral entry via conformational changes associated with binding the cell surface receptor (CD4) and coreceptor (CCR5/CXCR4), resulting in subsequent fusion of the viral and cellular membranes. While the gp120
Vinita R Joshi, Ruchi M Newman, Melissa L Pack, Karen A Power, James B Munro, Ken Okawa, Navid Madani, Joseph G Sodroski, Aaron G Schmidt, Todd M Allen   +9 more
doaj   +1 more source

A Role for Baculovirus GP41 in Budded Virus Production

Virology, 1997
Insect cells infected with tsB1074, a temperature-sensitive mutant of Autographa californica nuclear polyhedrosis virus, exhibit a "single-cell-infection" phenotype whereby the infection progresses through the very late phase culminating in occlusion body formation, but neighboring cells do not become infected.
Olszewski, Julie, Miller, Lois K.
openaire   +2 more sources

Comparative Evaluation of the New HIV VIDAS® DUO AG/AB Assay With DUO Ultra on Well Characterized Participants From the HIV‐1 Acute Infection French ANRS PRIMO Cohort

Journal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT Diagnosing HIV‐1 infection as early as the primary infection is crucial. In this context, we performed a comparative evaluation and agreement analysis of the newly proposed serological assay for the combined detection of total antibodies against HIV and P24 antigen (HIV VIDAS® DUO AG/AB, bioMérieux®), with the previously available HIV VIDAS ...
Gilbert Mchantaf, Xavier Maia, Valérie Andriantsoanirina, Océane Dehan, Karl Stefic, Laurent Hocqueloux, Olivier Robineau, Alain Makinson, Cécile Goujard, Laurence Meyer, Véronique Avettand‐Fenoel, ANRS PRIMO cohort   +11 more
wiley   +1 more source

HIV-1 gp41 extra-cellular domain.

, 2013
A scheme showing the functional regions within the extra-cellular portion of gp41 (aa 512–684).
Yechiel Shai (137126), Niv Antonovsky (362059), Irun R. Cohen (110065), Tomer Cohen (362057), Shmuel Jaffe Cohen (362058)   +4 more
core   +1 more source

Meeting Review: 2018 International Workshop on Structure and Function of the Lentiviral gp41 Cytoplasmic Tail

Viruses, 2018
Recent developments in defining the role of the lentiviral envelope glycoprotein (Env) cytoplasmic tail (CT) in Env trafficking and incorporation into virus particles have advanced our understanding of viral replication and transmission.
Melissa V. Fernandez, Eric O. Freed
doaj   +1 more source

Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated [PDF]

, 2011
The initial antibody response to HIV-1 is targeted to envelope (Env) gp41, and is nonneutralizing and ineffective in controlling viremia. To understand the origins and characteristics of gp41-binding antibodies produced shortly after HIV-1 transmission ...
Sonya L. Heath, Michael Egholm, Chen, Xi, Simen, Birgitte B, Bar, Katharine J, Haynes, Barton F, Denny, Thomas N, George C. Shaw, Boyd, Scott D, Boyd, Scott D., Egholm, Michael, S. Munir Alam, Eleanor Marshal, Zhang, Ruijun, Shaw, George C, Liao, Hua-Xin, Denny, Thomas N., Scott D. Boyd, Moody, M. Anthony, Xiaozhi Lu, Georgia D. Tomaras, Kepler, Thomas B, Marshall, Dawn J., Lu, Xiaozhi, Bar, Katharine J., Voss, Gerald, Xi Chen, Yu, Jae-Sung, Ruijun Zhang, Paul A. Goepfert, Munshaw, Supriya, Whitesides, John F, Thomas N. Denny, Shaw, George C., Gerald Voss, Alam, S Munir, Hwang, Kwan Ki, Feng Gao, Garnett Kelsoe, Montefiori, David C, Fire, Andrew Z., M. Anthony Moody, Goepfert, Paul A., Goepfert, Paul A, Heath, Sonya L., Simen, Birgitte B., Kelsoe, Garnett, Nathan Vandergrift, Kepler, Thomas B., Fire, Andrew Z, David C. Montefiori, Heath, Sonya L, Markowitz, Martin, Supriya Munshaw, Barton F. Haynes, Yu, Jae Sung, Andrew Z. Fire, Hwang, Kwan-Ki, Birgitte B. Simen, Thomas B. Kepler, Katharine J. Bar, Moody, M Anthony, Kwan-Ki Hwang, Gao, Feng, Whitesides, John F., Margolis, David M., Dawn J. Marshall, Marshall, Dawn J, David M. Margolis, Liao, Hua Xin, Marshal, Eleanor, Tomaras, Georgia D., John F. Whitesides, Hua-Xin Liao, Jae-Sung Yu, Alam, S. Munir, Martin Markowitz, Tomaras, Georgia D, Hanczaruk, Bozena, Montefiori, David C., Margolis, David M, Bozena Hanczaruk, Vandergrift, Nathan, Haynes, Barton F.   +83 more
core   +1 more source

Conditional Trimerization and Lytic Activity of HIV-1 gp41 Variants containing the Membrane-Associated Segments

Biochemistry, 2015
Fusion of host and viral membranes is a critical step during infection by membrane-bound viruses. The HIV-1 glycoproteins gp120 (surface subunit) and gp41 (fusion subunit) represent the prototypic system for studying this process; in the prevailing model,
Z. Dai, Yisong Tao, N. Liu, M. Brenowitz, M. Girvin, Jonathan R. Lai   +5 more
semanticscholar   +1 more source

Peptide mimic of the HIV envelope gp120-gp41 interface

, 2008
The human immunodeficiency virus envelope glycoprotein (Env) is composed of surface (gp120) and transmembrane (gp41) subunits, which are noncovalently associated on the viral surface. Human immunodeficiency virus Env mediates viral entry after undergoing
Michael S Kay⁎, Hong-Bo Pang, Sunghwan Kim   +2 more
core