Central nervous system paracoccidioidomycosis: analysis of 13 cases with immunofluorescence research of gp43 antigen [PDF]
Paracoccidioidomycosis (PCM) is a systemic granulomatous disease caused by Paracoccidioides brasiliensis, prevalent in Latin America, particularly in Brazil. Central nervous system (CNS) involvement occur in about 10% of cases, although such cases are uncommon in the literature […] Central nervous system paracoccidioidomycosis: analysis of 13 cases ...
Walter J. Fagundes-Pereyra
doaj +3 more sources
Cell-free antigens (CFAg) derived from Paracoccidioides brasiliensis have typically been used in immunodiffusion reactions for serodiagnosis or therapeutic follow-up of paracoccidioidomycosis patients.
Fecchio CJ +5 more
doaj +1 more source
Using quantitative glycome profiling of breast tumor interstitial fluid and matched serum, we identified N‐glycan pattern that (a) segregates tumor and normal interstitual fluids, (b) correlates with the presence of immune cells within tumor, (c) can be predictive for overall survival outcome of patients with breast cancer, and (d) can be detected in ...
Thilde Terkelsen +11 more
wiley +1 more source
Genotyping of the genus Paracoccidioides showed its diversity and geographical distribution. Four species constituting the Paracoccidioides brasiliensis complex and Paracoccidioides lutzii are etiological agents of paracoccidioidomycosis (PCM).
Edy F Pereira +9 more
doaj +1 more source
Polymorphism in the Gene Coding for the Immunodominant Antigen gp43 from the Pathogenic FungusParacoccidioides brasiliensis [PDF]
ABSTRACT The gp43 glycoprotein is an immune-dominant antigen in patients with paracoccidioidomycosis (PCM). It is protective against murine PCM and is a putative virulence factor. The gp43 gene of Paracoccidioides brasiliensis B-339 is located in a 1,329-bp DNA fragment that includes two exons, a 78-bp ...
F. Morais +4 more
semanticscholar +3 more sources
Detection of the basement membrane-degrading proteolytic activity of Paracoccidioides brasiliensis after SDS-PAGE using agarose overlays containing Abz-MKALTLQ-EDDnp [PDF]
We have characterized, in the Paracoccidioides brasiliensis yeast phase, an exocellular SH-dependent serine proteinase activity against Abz-MKRLTL-EDDnp and analogous fluorescent-quenched peptides, and showed that it is also active against constituents ...
Carmona, Adriana Karaoglanovic +4 more
core +4 more sources
The Environment and Cyanophage Diversity: Insights From Environmental Sequencing of DNA Polymerase
Globally distributed and abundant cyanophages in the family Myoviridae have dsDNA genomes with variable gene content, including host-derived auxiliary metabolic genes (AMGs) that potentially can facilitate viral replication.
Jan F. Finke +4 more
doaj +1 more source
Paracoccidioidomycosis: advances and unmet needs 100 years after its initial description by Lutz [PDF]
Universidade Federal de São Paulo (UNIFESP) Departamento de MedicinaUNIFESP, Depto.
Colombo, Arnaldo Lopes
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Diagnosis and Treatment of Paracoccidioidomycosis in the Maxillofacial Region: A Report of 5 Cases
Paracoccidioidomycosis is a fungal infection initially described in Brazil in 1908 by Adolfo Lutz. Manifestation of this disease depends on numerous factors, such as microorganism virulence, hormonal profile, genetic predisposition, nutrition, and immune system.
Antonio Dionízio De Albuquerque Neto +6 more
wiley +1 more source
New developments of RNAi in Paracoccidioides brasiliensis: prospects for high-throughput, genome-wide, functional genomics. [PDF]
The Fungal Genome Initiative of the Broad Institute, in partnership with the Paracoccidioides research community, has recently sequenced the genome of representative isolates of this human-pathogen dimorphic fungus: Pb18 (S1), Pb03 (PS2) and Pb01.
Tercio Goes +7 more
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