PURINE RECEPTORS: GPCR STRUCTURE AND AGONIST DESIGN [PDF]
, 2004 Kenneth A. Jacobson
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Mass Spectrometry Reviews, EarlyView.Abstract Cyclodepsipeptides (CDPs) represent a huge family of chemically and structurally diverse molecules with a wide ability for molecular interactions. CDPs are cyclic peptide‐related natural products made up of both proteinogenic and nonproteinogenic amino acids linked by amide and ester bonds.
Sophie Liuu +10 more
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Miniaturization of Whole Live Cell-Based GPCR Assays Using Microdispensing and Detection Systems [PDF]
, 2004 Oleg Kornienko +8 more
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Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking
Mass Spectrometry Reviews, EarlyView.ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu +4 more
wiley +1 more source
Editorial: GPCR and G Protein-Mediated Signalling Events in the Nervous System
Frontiers in Cellular Neuroscience, 2022 Yamina A. Berchiche, Terence E. Hébert
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Entropic Repulsion and Local Order in Doubly Tethered Polymers on a Surface
Macromolecular Theory and Simulations, EarlyView.The study examines the behavior of mobile doubly tethered polymers on a 2D substrate. It analyzes conformational properties and end‐monomer ordering, considering the director between end‐monomers for local ordering. As tethering density increases, a transition from mushroom‐like to upright structures is observed.
Min Chu, Dieter W. Heermann
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Light‐Activated Pharmacological Tools for Exploring the Cholinergic System
Medicinal Research Reviews, EarlyView.ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, and inflammation. Conventional cholinergic drugs generally suffer from poor selectivity and temporal precision, leading to undesired effects and limited therapeutic efficacy. Photopharmacology aims to
Alessio Colleoni +5 more
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GPCR-induced migration of breast carcinoma cells depends on both EGFR signal transactivation and EGFR-independent pathways [PDF]
, 2005 Stefan Hart +6 more
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Recent Developments in the Optical Control of Adrenergic Signaling
Medicinal Research Reviews, EarlyView.ABSTRACT Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the
Shuang Shi +4 more
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POST-TRANSCRIPTIONAL REGULATION OF KSHV G PROTEIN-COUPLED RECEPTOR (KSHV-GPCR)
, 1999 Elizabeth Geras‐Raaka +2 more
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