Results 191 to 200 of about 113,722 (335)

Plasmon-waveguide resonance (PWR) spectroscopy for directly viewing rates of GPCR/G-protein interactions and quantifying affinities [PDF]

, 2007
Victor J. Hruby, Gordon Tollin
openalex   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

DEP-Domain-Mediated Regulation of GPCR Signaling Responses

, 2006
Daniel R. Ballon, Paul L. Flanary, Douglas P. Gladue, James B. Konopka, Henrik Dohlman, Jeremy Thorner   +5 more
openalex   +1 more source

GPCR functional selectivity has therapeutic impact [PDF]

, 2007
Richard B. Mailman
openalex   +1 more source

Unraveling the role of GPCR signaling in metabolic reprogramming and immune microenvironment of lung adenocarcinoma: a multi-omics study with experimental validation. [PDF]

Front Immunol
Wang Z, Wang C, Zhao S, Gu C.
europepmc   +1 more source

Pharmacogenetics of follicle‐stimulating hormone action in the male

Andrology, EarlyView.
Abstract Male factor infertility (MFI) is involved in half of the cases of couple infertility. The follicle‐stimulating hormone (FSH) therapy is considered efficient to improve semen parameters and pregnancy rate in patients with idiopathic MFI, following the lesson learned from hypogonadotropic hypogonadism.
Andrea Graziani, Giuseppe Grande, Raffele Scafa, Riccardo Selice, Andrea Garolla, Maria Santa Rocca, Cinzia Vinanzi, Alberto Ferlin   +7 more
wiley   +1 more source

Author Correction: Simultaneous activation of CXC chemokine receptor 4 and histamine receptor H1 enhances calcium signaling and cancer cell migration

Scientific Reports
Chulo Park, Jin‑Woo Lee, Kiheon Kim, Dong‑Seung Seen, Jae‑Yeon Jeong, Won‑Ki Huh   +5 more
doaj   +1 more source

Impact of GPCRs in clinical medicine: Monogenic diseases, genetic variants and drug targets

, 2006
Paul A. Insel, Chih‐Min Tang, Ines N. Hahntow, Martin C. Michel   +3 more
openalex   +1 more source

EnGCI: enhancing GPCR-compound interaction prediction via large molecular models and KAN network. [PDF]

BMC Biol
Liu W, Li X, Hang B, Wang P.
europepmc   +1 more source

Comparative analysis of formyl peptide receptor 1 and formyl peptide receptor 2 reveals shared and preserved signalling profiles

British Journal of Pharmacology, EarlyView.
Background and Purpose The pattern recognition receptors, formyl peptide receptors, FPR1 and FPR2, are G protein‐coupled receptors that recognize many different pathogen‐ and host‐derived ligands. While FPR1 conveys pro‐inflammatory signals, FPR2 is linked with pro‐resolving outcomes.
Denise Pajonczyk, Merle F. Sternschulte, Oliver Soehnlein, Marcel Bermudez, Carsten A. Raabe, Ursula Rescher   +5 more
wiley   +1 more source