Results 111 to 120 of about 56,362 (206)

A Novel Monoallelic ALG5 Variant Causing Late-Onset ADPKD and Tubulointerstitial Fibrosis

Kidney International Reports
Introduction: Monoallelic variants in the ALG5 gene encoding asparagine-linked glycosylation protein 5 homolog (ALG5) have been recently shown to disrupt polycystin-1 (PC1) maturation and trafficking via underglycosylation, causing an autosomal dominant ...
Elhussein A.E. Elhassan, Tereza Kmochová, Katherine A. Benson, Neil K. Fennelly, Veronika Barešová, Kendrah Kidd, Brendan Doyle, Anthony Dorman, Martina M. Morrin, Niamh C. Kyne, Petr Vyleťal, Hana Hartmannová, Kateřina Hodaňová, Jana Sovová, Dita Mušálková, Alena Vrbacká, Anna Přistoupilová, Jan Živný, Klára Svojšová, Martin Radina, Viktor Stránecký, Dmitry Loginov, Petr Pompach, Petr Novák, Zdislava Vaníčková, Hana Hansíková, Silvie Rajnochová-Bloudíčková, Ondřej Viklický, Helena Hůlková, Gianpiero L. Cavalleri, Aleš Hnízda, Anthony J. Bleyer, Stanislav Kmoch, Peter J. Conlon, Martina Živná   +34 more
doaj   +1 more source

Erratum: A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor [PDF]

Nature, 1998
Robert D. Klein, Daniel Sherman, Wei-Hsien Ho, Donna Stone, Gregory L. Bennett, Barbara Moffat, Richard Vandlen, Laura Simmons, Qimin Gu, Jo-Anne Hongo, Brigitte Devaux, Kris Poulsen, Mark Armanini, Chika Nozaki, Naoya Asai, Audrey Goddard, Heidi Phillips, Chris E. Henderson, Masahide Takahashi, Arnon Rosenthal   +19 more
openaire   +1 more source

Apical membrane trafficking during regulated pancreatic exocrine secretion--role of alkaline pH in the acinar lumen and enzymatic cleavage of GP2, a GPI-linked protein.

European journal of cell biology, 1995
The GP2/THP family of glycosyl phosphatidylinositol (GPI)-anchored proteins is targeted to apical secretory compartments in polarized epithelial cells. We demonstrate in the rat exocrine pancreas that enzyme-mediated release of GP2 from acinar cell membranes represents a pH-dependent process regulated by bicarbonate secreted from ductular cells ...
S D, Freedman, H F, Kern, G A, Scheele
openaire   +1 more source

Lipid rafts: cell surface platforms for T cell signaling

Biological Research, 2002
The Src family tyrosine kinase Lck is essential for T cell development and T cell receptor (TCR)* signaling. Lck is post-translationally fatty acylated at its N-terminus conferring membrane targeting and concentration in plasma membrane lipid rafts ...
TONY MAGEE, NIINA PIRINEN, JEREMY ADLER, STAMATIS N PAGAKIS, INGELA PARMRYD   +4 more
doaj  

Cloning of a Carcinoembryonic Antigen Gene Family Member Expressed in Leukocytes of Chronic Myeloid Leukemia Patients and Bone Marrow [PDF]

, 1990
The carcinoembryonic antigen (CEA) gene family belongs to the immunoglobulin superfamily and can be subdivided into the CEA and pregnancy-specific glycoprotein subgroups.
Berling, Barbara, Brombacher, Frank, Buchegger, Franz, Grunert, Fritz, Kleist, Sabine von, Kolbinger, Frank, Thompson, John A., Zimmermann, Wolfgang   +7 more
core   +1 more source

Two lipid-anchored cAMP-binding proteins in the yeast Saccharomyces cerevisiae are unrelated to the R subunit of cytoplasmic protein kinase A [PDF]

, 1991
Bandlow, Wolfhard, Müller, Günter
core   +1 more source

Glucose induces lipolytic cleavage of a glycolipidic plasma membrane anchor in yeast [PDF]

, 1993
Bandlow, Wolfhard, Müller, Günter
core   +2 more sources

Paroxysmal nocturnal hemoglobinuria: pathophysiology, natural history and treatment options in the era of biological agents

Biologics: Targets & Therapy, 2008
Antonio M Risitano, Bruno RotoliHematology, Department of Biochemistry and Medical Biotechnologies, Federico II University of Naples, ItalyAbstract: Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal non-malignant hematological disease characterized ...
Antonio M Risitano, Bruno Rotoli
doaj  

The Emerging Roles of Protein Lipidation in Fertility and Reproductive Disorders: Mechanisms and Therapeutic Implications. [PDF]

Biomolecules
Cao H, Liu X, Zhu S, Nie H, Liu S, Fan J, Qin W.   +6 more
europepmc   +1 more source

Free GPIs and Comparison of GPI Structures Among Species. [PDF]

Int J Mol Sci
Ihim SA, Fujita M.
europepmc   +1 more source