Results 131 to 140 of about 508,309 (264)

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

open access: yesThe FEBS Journal, EarlyView.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka   +3 more
wiley   +1 more source

Semaphorin-7A is an erythrocyte receptor for P. falciparum merozoite-specific TRAP homolog, MTRAP.

open access: yesPLoS Pathogens, 2012
The motility and invasion of Plasmodium parasites is believed to require a cytoplasmic actin-myosin motor associated with a cell surface ligand belonging to the TRAP (thrombospondin-related anonymous protein) family.
S Josefin Bartholdson   +6 more
doaj   +1 more source

Translational control by the multi-KH domain protein Scp160 [PDF]

open access: yes, 2010
The control of mRNA translation mediated by RNA-binding proteins (RBPs) is a key player in modulating gene expression. In S. cerevisiae, the multi-KH domain protein Scp160 associates with a large number of mRNAs and is present on membrane-bound and, to a
Schreck, Heidrun
core  

Membrane‐type I metalloproteinase (MT1‐MMP): A key modifier of extracellular matrix microenvironment

open access: yesThe FEBS Journal, EarlyView.
MT1‐MMP: A cellular microenvironment modifier. MT1‐MMP is a major cellular microenvironment modifier, maintaining collagen homeostasis by degrading excess collagen (A), creating a migration path in motile cells such as cancer cells (B), modulating local microenvironmental signaling by cleaving transmembrane receptors (C), and destroying tissue ...
Yoshifumi Itoh, Masaki Inada
wiley   +1 more source

Chronic silencing of subsets of cortical layer 5 pyramidal neurons has a long‐term influence on the laminar distribution of parvalbumin interneurons and the perineuronal nets

open access: yesJournal of Anatomy, Volume 246, Issue 4, Page 479-504, April 2025.
Chronic silencing of subsets of layer 5 projection neurons has distinct effects on the laminar distribution of PV interneurons and the perineuronal nets in the adult primary motor and somatosensory cortex. Abstract Neural networks are established throughout cortical development, which require the right ratios of glutamatergic and GABAergic neurons ...
Florina P. Szabó   +4 more
wiley   +1 more source

Genetic Susceptibility to Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Effects of methylmercury exposure on the transcriptomes of cell lines from the rat central nervous system

open access: yesDiscover Toxicology
Methylmercury (MeHg) can have profound effects on cells of the nervous system, leading to DNA damage, oxidative stress, neuroinflammation, and cell death. In this study, transcriptomic changes in neuronal (B103) and glial (C6) cell lines from rat (Rattus
Laís Teixeira Bonfim   +3 more
doaj   +1 more source

GcrR in Streptococcus mutans Inhibits the Morphological Transition of Candida albicans Through Ras1–cAMP/PKA Pathway in the Cross‐Kingdom Biofilms

open access: yesMolecular Oral Microbiology, EarlyView.
ABSTRACT The dual‐species biofilms formed by Streptococcus mutans and Candida albicans exhibit enhanced cariogenic potential due to the production of extracellular polysaccharides (EPSs). The response regulator GcrR in S. mutans negatively regulates EPS synthesis, but its impact on dual‐species biofilms remains unclear.
Bin Zhang   +7 more
wiley   +1 more source

Rhamnogalacturonan‐II Dimerisation Reinforces Salt Resistance in Sugar Beet

open access: yesPlant, Cell &Environment, Volume 49, Issue 6, Page 3082-3100, June 2026.
ABSTRACT Salinity stress predominantly affects negatively charged cell wall polymers, for example, pectin. Excess Na+ ions interact physically and affect growth in stress‐sensitive plants. However, the salinity resistance of sugar beet cell walls remains unclear.
Shah Newaz Chowdhury   +5 more
wiley   +1 more source

Protein lipidation in health and disease: molecular basis, physiological function and pathological implication

open access: yesSignal Transduction and Targeted Therapy
Posttranslational modifications increase the complexity and functional diversity of proteins in response to complex external stimuli and internal changes.
Yuan Yuan   +5 more
doaj   +1 more source

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