Results 111 to 120 of about 34,844 (152)

Diverse ancestral myosin motors generate and segregate distinct types of nanocluster-rich domains at the plasma membrane

open access: yes
Sil P   +9 more
europepmc   +1 more source

POLARIZED SORTING OF GPI-LINKED PROTEINS IN EPITHELIA AND MEMBRANE MICRODOMAINS

Cell Biology International Reports, 1991
Taken together, our results with endogenous and transfected GPI-anchored proteins (summarized in Table 6) suggest that covalent attachment to GPI functions as an apical transport signal in polarized epithelial cells. This is the first example of a well-defined targeting signal for the post-Golgi sorting of plasma membrane proteins in polarized ...
M P, Lisanti, E, Rodríguez-Boulan
openaire   +2 more sources

Cellular Expression of a GPI-Linked T Cell Activation Protein

Cellular Immunology, 1994
A T cell activation protein was identified by generating a monoclonal antibody (anti-D2) against a gamma delta T cell receptor bearing gibbon ape T cell line (MLA144). Immunoprecipitation studies revealed three polypeptides of 180, 150, and 120 kDa. The antigen was also found to be expressed on endothelial cells in vivo and in vitro and on tumor cell ...
A, Haregewoin   +6 more
openaire   +2 more sources

Ectodomain interactions of leukocyte integrins and pro-inflammatory GPI-linked membrane proteins

Journal of Pharmaceutical and Biomedical Analysis, 1997
Although glycosylphosphatidyl-inositol (GPI) linked membrane proteins do not possess transmembrane or cytosolic sequences they elicit transmembrane signals. Using microscopic fluorescence imaging and resonance energy transfer (RET) techniques we have shown that certain pro-inflammatory GPI-linked membrane proteins can interact with leukocyte beta 2 ...
H R, Petty   +3 more
openaire   +2 more sources

Lipid Rafts, Caveolae and GPI-Linked Proteins

2012
Lipid rafts and caveolae are specialized membrane microdomains enriched in sphingolipids and cholesterol. They function in a variety of cellular processes including but not limited to endocytosis, transcytosis, signal transduction and receptor recycling.
Reeves, V.L.   +2 more
openaire   +3 more sources

The presence of GPI-linked protein(s) in an archaeobacterium, Sulfolobus acidocaldarius, closely related to eukaryotes

Biochimica et Biophysica Acta (BBA) - General Subjects, 1997
GPI-anchored proteins are distributed ubiquitously in eukaryotes, but not in procaryotes. By metabolic-labeling of Sulfolobus acidocaldarius cells, 14C-radiolabeled precursors of GPI and caldarchaetidylinositol were incorporated into 120, 143 and 185 kDa proteins.
T, Kobayashi, R, Nishizaki, H, Ikezawa
openaire   +2 more sources

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